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NCT05886634 · ClinicalTrials.gov registry record · Phase 2

A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcoma

A Phase 2 study of Sarcoma and Soft Tissue Sarcoma, sponsored by Memorial Sloan Kettering Cancer Center.

Active
Registry status
Phase 2
Development phase
16
Enrollment target
7
Study locations

NCT05886634 is a Phase 2 study of Sarcoma and Soft Tissue Sarcoma that is active but no longer recruiting, run by Memorial Sloan Kettering Cancer Center. The registered enrollment target is 16 participants, below the 921-participant average among 122 other Sarcoma trials with a reported enrollment target (98% lower). The trial reports 7 study locations across 2 states.

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The verdict

NCT05886634, a Phase 2 study of Sarcoma and Soft Tissue Sarcoma, is active but no longer recruiting, sponsored by Memorial Sloan Kettering Cancer Center.

ACTIVE NOT RECRUITING
Registry status
Phase 2
Development phase
16 participants
Enrollment target
7
Study locations

Study Summary

Participants will have a diagnosis of dedifferentiated liposarcoma (DDLS) that has spread beyond its original location (advanced). In addition, their DDLS either has come back after treatment (recurrent), has spread to different parts of your body (metastatic), or is unable to be removed surgically (unresectable). The purpose of this study is to find out whether the combination of etrumadenant and zimberelimab is an effective treatment for people with advanced DDLS.

Interventions

  • DRUG Zimberelimab
  • DRUG Etrumadenant

Study Locations (7)

New York

  • Memorial Sloan Kettering Suffolk - Commack (Limited Protocol Activities) - Commack
  • Memorial Sloan Kettering Westchester (Limited Protocol Activities) - Harrison
  • Memorial Sloan Kettering Cancer Center - New York
  • Memorial Sloan Kettering Nassau (Limited protocol activities) - Rockville Centre

New Jersey

  • Memorial Sloan Kettering at Basking Ridge (Limited Protocol Activities) - Basking Ridge
  • Memorial Sloan Kettering Monmouth (Limited Protocol Activities) - Middletown
  • Memorial Sloan Kettering Bergen (Limited Protocol Activities) - Montvale

Trial Details

FieldValue
Enrollment Target 16 participants
Start Date 2023-05-23
Est. Completion 2027-05-23
Phase Phase 2

Sponsor

Memorial Sloan Kettering Cancer Center

1,884 total trials

What the Registry Record Tells You About NCT05886634

The ClinicalTrials.gov registry entry for NCT05886634 describes a study currently listed as active not recruiting, categorized as Phase 2. The registered enrollment target is 16 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 921-participant average among 122 other Sarcoma trials with a reported enrollment target (98% lower). The listed sponsor is Memorial Sloan Kettering Cancer Center, which has 1,884 total studies on file at ClinicalTrials.gov.

The record links to 7 conditions, with Sarcoma appearing as the primary indexed condition, and to 2 interventions - of which Zimberelimab is the first listed.

NCT05886634 reports 7 study locations spanning 2 distinct geographic areas - top geographies include New York, New Jersey.

Frequently Asked Questions

What is clinical trial NCT05886634 about?

NCT05886634 is a clinical study titled "A Study of Etrumadenant and Zimberelimab in People With Dedifferentiated Liposarcoma". Participants will have a diagnosis of dedifferentiated liposarcoma (DDLS) that has spread beyond its original location (advanced). In addition, their DDLS either has come back after treatment (recurrent), has spread to different parts of your body (metastatic), or is unable to be removed surgically ...

What is the current status of trial NCT05886634?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 16 participants. The study started on 2023-05-23. Estimated completion is 2027-05-23.

What conditions does trial NCT05886634 study?

This clinical trial studies the following conditions: Sarcoma, Soft Tissue Sarcoma, Sarcoma,Soft Tissue, Metastatic Dedifferentiated Liposarcoma, Unresectable Dedifferentiated Liposarcoma.

What interventions are being tested in trial NCT05886634?

The interventions under investigation include: Zimberelimab (DRUG), Etrumadenant (DRUG).

Who is sponsoring clinical trial NCT05886634?

This trial is sponsored by Memorial Sloan Kettering Cancer Center, which has 1,884 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT05886634 being conducted?

This trial has 7 study locations across New Jersey, New York. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.