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NCT04765345 · ClinicalTrials.gov registry record
Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F
A clinical trial of Retinitis Pigmentosa and Retinal Degeneration, sponsored by Jaeb Center for Health Research.
- Active
- Registry status
- 44
- Enrollment target
- 10
- Study locations
NCT04765345: Active study of Retinitis Pigmentosa and Retinal Degeneration, sponsored by Jaeb Center for Health Research.
NCT04765345 is a study of Retinitis Pigmentosa and Retinal Degeneration that is active but no longer recruiting, run by Jaeb Center for Health Research. The registered enrollment target is 44 participants, below the 260-participant average among 37 other Retinitis Pigmentosa trials with a reported enrollment target (83% lower). The trial reports 10 study locations across 5 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04765345, a study of Retinitis Pigmentosa and Retinal Degeneration, is active but no longer recruiting, sponsored by Jaeb Center for Health Research.
- ACTIVE NOT RECRUITING
- Registry status
- 44 participants
- Enrollment target
- 10
- Study locations
Study Summary
The overall goal of this project, co-funded by the Foundation Fighting Blindness and the USHER 1F Collaborative is to characterize the natural history of disease progression in patients with PCDH15 mutations in order to accelerate the development of outcome measures for clinical trials.
Primary Outcome
measured by static perimetry with quantitative, topographic analysis (Hill of Vision) and assessed by a central reading center
Conditions Studied
Study Locations (10)
Other
- CHNO des Quinze-Vingts - Paris
- University of Tubingen - Tübingen
- Haddassah Medical Center - Jerusalem
- Radboud University - Nijmegen
- University Hospital Basel - Basel
- Moorfields Eye Hospital - London
California
- University of California, San Francisco - San Francisco
Maryland
- The Johns Hopkins Wilmer Eye Institute - Baltimore
North Carolina
- Duke University, Duke Eye Center - Durham
Ontario
- Hospital for Sick Children - Toronto
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 44 participants |
| Start Date | 2021-06-08 |
| Est. Completion | 2027-06-30 |
What the registry record for NCT04765345 still lists
NCT04765345 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 44 participants, a relatively small participant target, below the 260-participant average among 37 other Retinitis Pigmentosa trials with a reported enrollment target (83% lower).
The record links to 3 conditions, with Retinitis Pigmentosa appearing as the primary indexed condition, and to 0 interventions.
NCT04765345 lists 10 locations in 5 states (Other, California, Maryland).
Frequently Asked Questions
What is clinical trial NCT04765345 about?
NCT04765345 is a clinical study titled "Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F". The overall goal of this project, co-funded by the Foundation Fighting Blindness and the USHER 1F Collaborative is to characterize the natural history of disease progression in patients with PCDH15 mutations in order to accelerate the development of outcome measures for clinical trials.
What is the current status of trial NCT04765345?
This trial is currently active not recruiting. The enrollment target is 44 participants. The study started on 2021-06-08. Estimated completion is 2027-06-30.
What conditions does trial NCT04765345 study?
This clinical trial studies the following conditions: Retinitis Pigmentosa, Retinal Degeneration, Eye Diseases, Hereditary.
Who is sponsoring clinical trial NCT04765345?
This trial is sponsored by Jaeb Center for Health Research, which has 119 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04765345 being conducted?
This trial has 10 study locations across California, Maryland, North Carolina, Ontario. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Retinitis Pigmentosa
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04765345's enrollment target sits among peer trials
44 18th of 37 higher than 20 of 37 other Retinitis Pigmentosa trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Retinitis Pigmentosa trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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