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NCT01866371 · ClinicalTrials.gov registry record
High Resolution Retinal Imaging
A clinical trial of Age-related Macular Degeneration and Retinitis Pigmentosa, sponsored by University of Pennsylvania.
- Recruiting
- Registry status
- 600
- Enrollment target
- 1
- Study location
NCT01866371: Recruiting study of Age-related Macular Degeneration and Retinitis Pigmentosa, sponsored by University of Pennsylvania.
NCT01866371 is a study of Age-related Macular Degeneration and Retinitis Pigmentosa that is actively recruiting participants, run by University of Pennsylvania. The registered enrollment target is 600 participants, below the 1,500-participant average among 74 other Age-related Macular Degeneration trials with a reported enrollment target (60% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01866371, a study of Age-related Macular Degeneration and Retinitis Pigmentosa, is actively recruiting participants, sponsored by University of Pennsylvania.
- RECRUITING
- Registry status
- 600 participants
- Enrollment target
- 1
- Study location
Study Summary
Studying the morphology and function of the normal and diseased retina in vivo is needed for advancing the detection, diagnosis, and treatment of retinal disease. This protocol uses an adaptive optics scanning laser ophthalmoscope (AOSLO) to image the normal and diseased retina with individual cellular resolution non-invasively. The primary objective of this study is to obtain and analyze high-resolution images of the retina, in particular by imaging the cone photoreceptor mosaic, the retinal vasculature and other retinal layers. The study design will involve case-control studies, where cases are followed over time. Subjects age 7 and older may be invited to participate. The main research procedure involves retinal imaging with the AOSLO. The primary endpoint is the observation of differences in retinal images between subjects with and without retinal diseases. These changes will be quantified by examining the cell density, size, spacing and regularity of the cone photoreceptor mosaic, as well as examining the differences between other retinal layers.
Primary Outcome
The primary objective of this study is to obtain and analyze high-resolution images of the retina in normal and diseased eyes non-invasively.
Conditions Studied
Interventions
- PROCEDURE Retinal imaging
Study Locations (1)
Pennsylvania
- University of Pennsylvania - Philadelphia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2013-05 |
| Est. Completion | 2027-12 |
What NCT01866371 shows while recruiting
NCT01866371 is an observational study that tracks outcomes without assigning an intervention. The registered 600 participants enrollment target is mid-sized for trials with a published cap, below the 1,500-participant average among 74 other Age-related Macular Degeneration trials with a reported enrollment target (60% lower).
The record links to 5 conditions, with Age-related Macular Degeneration appearing as the primary indexed condition, and to 1 intervention - of which Retinal imaging is the first listed.
NCT01866371 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT01866371 about?
NCT01866371 is a clinical study titled "High Resolution Retinal Imaging". Studying the morphology and function of the normal and diseased retina in vivo is needed for advancing the detection, diagnosis, and treatment of retinal disease. This protocol uses an adaptive optics scanning laser ophthalmoscope (AOSLO) to image the normal and diseased retina with individual cellu...
What is the current status of trial NCT01866371?
This trial is currently recruiting. The enrollment target is 600 participants. The study started on 2013-05. Estimated completion is 2027-12.
What conditions does trial NCT01866371 study?
This clinical trial studies the following conditions: Age-related Macular Degeneration, Retinitis Pigmentosa, Geographic Atrophy, Choroideremia, Stargardts.
What interventions are being tested in trial NCT01866371?
The interventions under investigation include: Retinal imaging (PROCEDURE).
Who is sponsoring clinical trial NCT01866371?
This trial is sponsored by University of Pennsylvania, which has 1,423 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01866371 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Age-related Macular Degeneration
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01866371's enrollment target sits among peer trials
600 9th of 74 higher than 66 of 74 other Age-related Macular Degeneration trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Age-related Macular Degeneration trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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