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RECRUITING Phase 2

Safety of a Single, Intravitreal Injection of 6.0M jCell (Famzeretcel) in Retinitis Pigmentosa (RP)

NCT06912633 · View on ClinicalTrials.gov ↗

Study Summary

This study evaluates the safety of a single injection of jCell (famzeretcel) comprising 6.0 million (6.0M) retinal progenitor cells over a six-month study period in a cohort of adult subjects with RP. Additionally, changes in visual function will be evaluated at six months between the active treatment group (6.0M jCell) compared to sham-treated controls.

Conditions Studied

Interventions

  • BIOLOGICAL human retinal progenitor cells
  • OTHER Mock injection

Study Locations (14)

California

  • California Retina Consultants — Bakersfield
  • Retina-Vitreous Associates Medical Group — Beverly Hills
  • Gavin Herbert Eye Institute, UC Irvine — Irvine
  • Retina Consultants Medical Group — Sacramento
  • Bay Area Retina Associates — Walnut Creek

Texas

  • Retina Consultants of Texas: Bellaire Retina Center — Bellaire
  • Retina Consultants of Texas: San Antonio — San Antonio

Arizona

  • Associated Retina Consultants — Phoenix

Florida

  • Vitreo Retinal Associates — Gainesville

Georgia

  • Georgia Retina — Marietta

Illinois

  • Illinois Retina Associates — Oak Park

New Jersey

  • NJRetina — Teaneck

New York

  • Long Island Vitreoretinal Consultants — Westbury

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2025-06-20
Est. Completion 2026-09
Phase Phase 2

Sponsor

jCyte

2 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT06912633

The ClinicalTrials.gov registry entry for NCT06912633 describes a study currently listed as recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 60 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is jCyte, which has 2 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Retinitis Pigmentosa appearing as the primary indexed condition, and to 2 interventions — of which human retinal progenitor cells is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT06912633 reports 14 study locations spanning 9 distinct geographic areas — top geographies include California, Texas, Arizona. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT06912633 about?

NCT06912633 is a clinical study titled "Safety of a Single, Intravitreal Injection of 6.0M jCell (Famzeretcel) in Retinitis Pigmentosa (RP)". This study evaluates the safety of a single injection of jCell (famzeretcel) comprising 6.0 million (6.0M) retinal progenitor cells over a six-month study period in a cohort of adult subjects with RP. Additionally, changes in visual function will be evaluated at six months between the active treatme...

What is the current status of trial NCT06912633?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2025-06-20. Estimated completion is 2026-09.

What conditions does trial NCT06912633 study?

This clinical trial studies the following conditions: Retinitis Pigmentosa. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT06912633?

The interventions under investigation include: human retinal progenitor cells (BIOLOGICAL), Mock injection (OTHER). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT06912633?

This trial is sponsored by jCyte, which has 2 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT06912633 being conducted?

This trial has 14 study locations across Arizona, California, Florida, Georgia, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial