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NCT05355415 · ClinicalTrials.gov registry record
Adaptive Optics Imaging of Outer Retinal Diseases
A clinical trial of Age-related Macular Degeneration and Retinitis Pigmentosa, sponsored by Food and Drug Administration (FDA).
- Recruiting
- Registry status
- 100
- Enrollment target
- 2
- Study locations
NCT05355415: Recruiting study of Age-related Macular Degeneration and Retinitis Pigmentosa, sponsored by Food and Drug Administration (FDA).
NCT05355415 is a study of Age-related Macular Degeneration and Retinitis Pigmentosa that is actively recruiting participants, run by Food and Drug Administration (FDA). The registered enrollment target is 100 participants, below the 1,506-participant average among 74 other Age-related Macular Degeneration trials with a reported enrollment target (93% lower). The trial reports 2 study locations across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05355415, a study of Age-related Macular Degeneration and Retinitis Pigmentosa, is actively recruiting participants, sponsored by Food and Drug Administration (FDA).
- RECRUITING
- Registry status
- 100 participants
- Enrollment target
- 2
- Study locations
Study Summary
The objective of the study is to collect adaptive optics (AO) retinal images from human subjects with outer retinal diseases (diseases of the outer retina including photoreceptor, retinal pigment epithelium (RPE), basement membrane or choroidal pathologies) to develop new diagnostic methods, biomarkers, and clinical endpoints.
Primary Outcome
PR density will be calculated at specific retinal eccentricities from cells counted in average AO-OCT volumes or average AOSLO frames.
Conditions Studied
Interventions
- DEVICE Adaptive optics imaging
Study Locations (2)
Maryland
- NIH Clinical Center - Bethesda
- Food and Drug Administration - Silver Spring
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2021-08-27 |
| Est. Completion | 2026-08-27 |
What NCT05355415 shows while recruiting
NCT05355415 is an observational study that tracks outcomes without assigning an intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 1,506-participant average among 74 other Age-related Macular Degeneration trials with a reported enrollment target (93% lower).
The record links to 10 conditions, with Age-related Macular Degeneration appearing as the primary indexed condition, and to 1 intervention - of which Adaptive optics imaging is the first listed.
NCT05355415 reports a single indexed study location in Maryland.
Frequently Asked Questions
What is clinical trial NCT05355415 about?
NCT05355415 is a clinical study titled "Adaptive Optics Imaging of Outer Retinal Diseases". The objective of the study is to collect adaptive optics (AO) retinal images from human subjects with outer retinal diseases (diseases of the outer retina including photoreceptor, retinal pigment epithelium (RPE), basement membrane or choroidal pathologies) to develop new diagnostic methods, biomark...
What is the current status of trial NCT05355415?
This trial is currently recruiting. The enrollment target is 100 participants. The study started on 2021-08-27. Estimated completion is 2026-08-27.
What conditions does trial NCT05355415 study?
This clinical trial studies the following conditions: Age-related Macular Degeneration, Retinitis Pigmentosa, Retinal Degeneration, Cone-Rod Dystrophy, Cone Dystrophy.
What interventions are being tested in trial NCT05355415?
The interventions under investigation include: Adaptive optics imaging (DEVICE).
Who is sponsoring clinical trial NCT05355415?
This trial is sponsored by Food and Drug Administration (FDA), which has 23 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05355415 being conducted?
This trial has 2 study locations across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT05355415's enrollment target sits among peer trials
100 31st of 74 higher than 42 of 74 other Age-related Macular Degeneration trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Age-related Macular Degeneration trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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