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Pulmonary Disease, Chronic Obstructive clinical trials
7 of 75 indexed Pulmonary Disease, Chronic Obstructive trials are currently recruiting.
75 US clinical trials · 7 currently recruiting
Pulmonary Disease, Chronic Obstructive is the subject of 75 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 34 are in Phase 3-4 (later-stage) and 20 in Phase 1-2 (earlier-stage). The most active sponsor is GlaxoSmithKline, running 30 of these trials.
The research picture
Pulmonary Disease, Chronic Obstructive has 75 registered US clinical trials, 7 of them open to new participants right now, about 9% of the total.
- 7
- recruiting participants now
- 9%
- of trials open to enrollment
- 34
- in Phase 3–4 (later-stage)
- 30
- top sponsor: GlaxoSmithKline
Active & Recent Trials
75 total, page 2 of 2
A Cognitive-Behavioral Intervention for Depression and Anxiety in COPD
US Department of Veterans Affairs
NCT00105911
Bone Mineral Density Study In Patients With Chronic Obstructive Pulmonary Disease. DISKUS® Inhaler is a Trademark of the GSK Group of Companies.
GlaxoSmithKline
NCT00355342
Outlook: An Intervention to Improve Quality of Life in Serious Illness
Duke University
NCT00939146
A Blinded Study Comparing the Safety and Efficacy of a Fully Human Anti-IL8 Monoclonal Antibody (ABX-IL8) to Placebo in Patients With Chronic Bronchitis and COPD
Abgenix
NCT00035828
Efficacy and Safety Comparison of Tiotropium Inhalation Solution (Respimat Inhaler) and Spiriva HandiHaler in COPD
Boehringer Ingelheim
NCT00239447
Problem-Solving Therapy for People With Major Depression and Chronic Obstructive Pulmonary Disease
Weill Medical College of Cornell University
NCT00601055
A Long-term Safety Study of Infliximab in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD).
Centocor
NCT00380796
Investigate the Impact of Early Treatment Initiation With Tiotropium in Patients Recovering From Hospitalization for an Acute COPD Exacerbation 2
Boehringer Ingelheim
NCT01662986
Safety and Tolerability of Repeat Dosing of GSK233705/GW642444 in COPD
GlaxoSmithKline
NCT00749411
Pharmacokinetic Study in Healthy Volunteers to Characterise the Exposure of Fluticasone Furoate (FF), Vilanterol (VI) and Umeclidinium (UMEC) at Two Different Doses
GlaxoSmithKline
NCT01894386
Association Between Increased Oxidative Stress, Anti-Inflammatory Fatty Acid Formation, and Airway Infection in People With Asthma and Chronic Obstructive Pulmonary Disease
Brigham and Women's Hospital
NCT00595114
Changes in Cytokine Levels During an Acute Exacerbation of Chronic Obstructive Pulmonary Disease
University of Michigan
NCT00281242
Peripheral Nerve Blocks for Above-the-knee Amputations
University of Florida
NCT03404180
A Study to Investigate the Safety and Pharmacokinetics of a Single Dose of GSK2256294 in Healthy Young Males and Elderly Subjects
GlaxoSmithKline
NCT02006537
Transforming Psychotherapy for Chronically Ill Patients
US Department of Veterans Affairs
NCT00520429
Cathelicidin and Vitamin D: Impact on Populations At-Risk and With COPD
University of North Carolina, Chapel Hill
NCT02464059
Study to Evaluate the Safety, Tolerability and Pharmacokinetics of GSK2269557 Administered Via the ELLIPTA Dry Powder Inhaler to Healthy Subjects
GlaxoSmithKline
NCT02691325
Tolerability of Metoprolol-Succinate-ER and Carvedilol in COPD
VA Greater Los Angeles Healthcare System
NCT03370835
The Trajectory of Physical Activity Following Pulmonary Rehabilitation
Trinity Health Of New England
NCT02399254
A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics (PK) of Nemiralisib
GlaxoSmithKline
NCT03398421
Real-Time Support for Exercise Persistence in COPD
University of Washington
NCT00373932
Oxygen Savings With Administered Oxygen and High Flow Ambient Air At Rest
Johns Hopkins University
NCT04170062
Abdominal Functional Electrical Stimulation to Reduce Hyperinflation in Chronic Obstructive Pulmonary Disease Patients
Liberate Medical
NCT02035228
Home COPD and Open Ventilation Evaluation (HOPE) Study
Landon Pediatric Foundation
NCT03691181
Proof of Concept Study Assessing Technology-Assisted Respiratory Adherence Prototype Version 3 in Individuals With COPD
Boehringer Ingelheim
NCT04795323
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 13 |
| Phase 3 | 22 |
| Phase 4 | 12 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Pulmonary Disease, Chronic Obstructive Trial Landscape
75 indexed Pulmonary Disease, Chronic Obstructive studies · 7 recruiting (9%).
Phase mix: 34 late (III/IV) vs 20 early (I/II).
Top sponsor: GlaxoSmithKline (30 trials), 9 others listed. 25 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Pulmonary Disease, Chronic Obstructive?
PlainTrial tracks 75 US clinical trials for Pulmonary Disease, Chronic Obstructive, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Pulmonary Disease, Chronic Obstructive?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.