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ClinicalTrials.gov 7 recruiting now later-stage tilt

Pulmonary Disease, Chronic Obstructive: later-stage trial registry

7 of 75 indexed Pulmonary Disease, Chronic Obstructive trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #178 of 28,707 conditions by registered trial count.

75 US clinical trials · 7 currently recruiting · #178 of 28,707 conditions by registered trial count

Pulmonary Disease, Chronic Obstructive: 75 US clinical trials tracked, 7 recruiting.

Pulmonary Disease, Chronic Obstructive is the subject of 75 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 34 are in Phase 3-4 (later-stage) and 20 in Phase 1-2 (earlier-stage). The most active sponsor is GlaxoSmithKline, running 30 of these trials.

Enrollment posture brief

Registry condition pulmonary-disease-chronic-obstructive

OPEN 7 | RECR 9% | LATE 34 | EARLY 20 | RANK #178 | SPON 30

Nearest open-share peer: Visual Acuity (10% recruiting · 21 trials)

Acute Kidney Injury44%Infertility33.3%Age-related Macular Degenera26.7%Tobacco Use Disorder25.3%Pulmonary Disease, Chron (th…9%
Open-enrollment share among volume-matched conditions near Pulmonary Disease, Chronic Obstructive

Pulmonary Disease, Chronic Obstructive lists 7 open slots (9% of 75 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Pulmonary Disease, Chronic Obstructive on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Pulmonary Disease, Chronic Obstructive is recruiting below its size-band peers.

    7 of 75 indexed trials (9.3%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Pulmonary Disease, Chronic Obstructive research.

    GlaxoSmithKline accounts for 30 of 75 trials (40%). 29 distinct sponsors appear on at least one study for this condition label.

  3. Typical Pulmonary Disease, Chronic Obstructive enrolment sits around 295 participants.

    Median target enrolment is 295 among the 75 trials that report a genuine target (sentinel values excluded). 22 of those (29.3%) plan for fewer than 100 participants.

  4. Pulmonary Disease, Chronic Obstructive research is mostly interventional.

    66 interventional and 9 observational studies make up this index (88% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 213Phase 322Phase 412

Open and recent trials

75 total, page 2 of 2

COMPLETED NA 222 participants

A Cognitive-Behavioral Intervention for Depression and Anxiety in COPD

US Department of Veterans Affairs

NCT00105911

COMPLETED Phase 4 186 participants

Bone Mineral Density Study In Patients With Chronic Obstructive Pulmonary Disease. DISKUS® Inhaler is a Trademark of the GSK Group of Companies.

GlaxoSmithKline

NCT00355342

COMPLETED NA 154 participants

Outlook: An Intervention to Improve Quality of Life in Serious Illness

Duke University

NCT00939146

COMPLETED Phase 2 150 participants

A Blinded Study Comparing the Safety and Efficacy of a Fully Human Anti-IL8 Monoclonal Antibody (ABX-IL8) to Placebo in Patients With Chronic Bronchitis and COPD

Abgenix

NCT00035828

COMPLETED Phase 3 131 participants

Efficacy and Safety Comparison of Tiotropium Inhalation Solution (Respimat Inhaler) and Spiriva HandiHaler in COPD

Boehringer Ingelheim

NCT00239447

COMPLETED NA 101 participants

Problem-Solving Therapy for People With Major Depression and Chronic Obstructive Pulmonary Disease

Weill Medical College of Cornell University

NCT00601055

COMPLETED 88 participants

A Long-term Safety Study of Infliximab in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD).

Centocor

NCT00380796

COMPLETED Phase 4 79 participants

Investigate the Impact of Early Treatment Initiation With Tiotropium in Patients Recovering From Hospitalization for an Acute COPD Exacerbation 2

Boehringer Ingelheim

NCT01662986

COMPLETED Phase 2 61 participants

Safety and Tolerability of Repeat Dosing of GSK233705/GW642444 in COPD

GlaxoSmithKline

NCT00749411

COMPLETED Phase 1 48 participants

Pharmacokinetic Study in Healthy Volunteers to Characterise the Exposure of Fluticasone Furoate (FF), Vilanterol (VI) and Umeclidinium (UMEC) at Two Different Doses

GlaxoSmithKline

NCT01894386

COMPLETED 43 participants

Association Between Increased Oxidative Stress, Anti-Inflammatory Fatty Acid Formation, and Airway Infection in People With Asthma and Chronic Obstructive Pulmonary Disease

Brigham and Women's Hospital

NCT00595114

COMPLETED 37 participants

Changes in Cytokine Levels During an Acute Exacerbation of Chronic Obstructive Pulmonary Disease

University of Michigan

NCT00281242

COMPLETED Phase 4 30 participants

Peripheral Nerve Blocks for Above-the-knee Amputations

University of Florida

NCT03404180

COMPLETED Phase 1 28 participants

A Study to Investigate the Safety and Pharmacokinetics of a Single Dose of GSK2256294 in Healthy Young Males and Elderly Subjects

GlaxoSmithKline

NCT02006537

COMPLETED Phase 1 23 participants

Transforming Psychotherapy for Chronically Ill Patients

US Department of Veterans Affairs

NCT00520429

COMPLETED Phase 2 23 participants

Cathelicidin and Vitamin D: Impact on Populations At-Risk and With COPD

University of North Carolina, Chapel Hill

NCT02464059

COMPLETED Phase 1 22 participants

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of GSK2269557 Administered Via the ELLIPTA Dry Powder Inhaler to Healthy Subjects

GlaxoSmithKline

NCT02691325

COMPLETED Phase 4 21 participants

Tolerability of Metoprolol-Succinate-ER and Carvedilol in COPD

VA Greater Los Angeles Healthcare System

NCT03370835

COMPLETED 21 participants

The Trajectory of Physical Activity Following Pulmonary Rehabilitation

Trinity Health Of New England

NCT02399254

COMPLETED Phase 1 20 participants

A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics (PK) of Nemiralisib

GlaxoSmithKline

NCT03398421

COMPLETED Phase 1 17 participants

Real-Time Support for Exercise Persistence in COPD

University of Washington

NCT00373932

COMPLETED NA 11 participants

Oxygen Savings With Administered Oxygen and High Flow Ambient Air At Rest

Johns Hopkins University

NCT04170062

COMPLETED NA 7 participants

Abdominal Functional Electrical Stimulation to Reduce Hyperinflation in Chronic Obstructive Pulmonary Disease Patients

Liberate Medical

NCT02035228

COMPLETED NA 6 participants

Home COPD and Open Ventilation Evaluation (HOPE) Study

Landon Pediatric Foundation

NCT03691181

COMPLETED Phase 2 5 participants

Proof of Concept Study Assessing Technology-Assisted Respiratory Adherence Prototype Version 3 in Individuals With COPD

Boehringer Ingelheim

NCT04795323

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Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 13
Phase 3 22
Phase 4 12

Named interventions

Most-linked intervention names on Pulmonary Disease, Chronic Obstructive records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
12 trials
tiotropium Drug
6 trials
tiotropium bromide Drug
3 trials
olodaterol Drug
3 trials
Tiotropium Drug
3 trials
Depemokimab Drug
3 trials
GW642444 25mcg Drug
2 trials
Salbutamol as needed Drug
2 trials

US sites by state

Facility locations filed on Pulmonary Disease, Chronic Obstructive trials. A trial with sites in several states counts in each.

California 33 trials
Florida 32 trials
Alabama 28 trials
South Carolina 26 trials
North Carolina 22 trials
Missouri 17 trials
Connecticut 16 trials
Texas 15 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Pulmonary Disease, Chronic Obstructive page

75 registered trials, 7 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 7 Pulmonary Disease, Chronic Obstructive trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • GlaxoSmithKline sponsors the most Pulmonary Disease, Chronic Obstructive trials on record, review their full trial history before evaluating a specific study. See GlaxoSmithKline's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pulmonary Disease, Chronic Obstructive condition card totals 75 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.