Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 7 recruiting now official registry

Pulmonary Disease, Chronic Obstructive clinical trials

7 of 75 indexed Pulmonary Disease, Chronic Obstructive trials are currently recruiting.

75 US clinical trials · 7 currently recruiting

Pulmonary Disease, Chronic Obstructive is the subject of 75 registered US clinical trials on ClinicalTrials.gov, 7 of them currently open to new participants. 34 are in Phase 3-4 (later-stage) and 20 in Phase 1-2 (earlier-stage). The most active sponsor is GlaxoSmithKline, running 30 of these trials.

The research picture

Pulmonary Disease, Chronic Obstructive has 75 registered US clinical trials, 7 of them open to new participants right now, about 9% of the total.

7
recruiting participants now
9%
of trials open to enrollment
34
in Phase 3–4 (later-stage)
30
top sponsor: GlaxoSmithKline
Phase 17Phase 213Phase 322Phase 412

Active & Recent Trials

75 total, page 2 of 2

COMPLETED NA 222 participants

A Cognitive-Behavioral Intervention for Depression and Anxiety in COPD

US Department of Veterans Affairs

NCT00105911

COMPLETED Phase 4 186 participants

Bone Mineral Density Study In Patients With Chronic Obstructive Pulmonary Disease. DISKUS® Inhaler is a Trademark of the GSK Group of Companies.

GlaxoSmithKline

NCT00355342

COMPLETED NA 154 participants

Outlook: An Intervention to Improve Quality of Life in Serious Illness

Duke University

NCT00939146

COMPLETED Phase 2 150 participants

A Blinded Study Comparing the Safety and Efficacy of a Fully Human Anti-IL8 Monoclonal Antibody (ABX-IL8) to Placebo in Patients With Chronic Bronchitis and COPD

Abgenix

NCT00035828

COMPLETED Phase 3 131 participants

Efficacy and Safety Comparison of Tiotropium Inhalation Solution (Respimat Inhaler) and Spiriva HandiHaler in COPD

Boehringer Ingelheim

NCT00239447

COMPLETED NA 101 participants

Problem-Solving Therapy for People With Major Depression and Chronic Obstructive Pulmonary Disease

Weill Medical College of Cornell University

NCT00601055

COMPLETED 88 participants

A Long-term Safety Study of Infliximab in Patients With Moderate to Severe Chronic Obstructive Pulmonary Disease (COPD).

Centocor

NCT00380796

COMPLETED Phase 4 79 participants

Investigate the Impact of Early Treatment Initiation With Tiotropium in Patients Recovering From Hospitalization for an Acute COPD Exacerbation 2

Boehringer Ingelheim

NCT01662986

COMPLETED Phase 2 61 participants

Safety and Tolerability of Repeat Dosing of GSK233705/GW642444 in COPD

GlaxoSmithKline

NCT00749411

COMPLETED Phase 1 48 participants

Pharmacokinetic Study in Healthy Volunteers to Characterise the Exposure of Fluticasone Furoate (FF), Vilanterol (VI) and Umeclidinium (UMEC) at Two Different Doses

GlaxoSmithKline

NCT01894386

COMPLETED 43 participants

Association Between Increased Oxidative Stress, Anti-Inflammatory Fatty Acid Formation, and Airway Infection in People With Asthma and Chronic Obstructive Pulmonary Disease

Brigham and Women's Hospital

NCT00595114

COMPLETED 37 participants

Changes in Cytokine Levels During an Acute Exacerbation of Chronic Obstructive Pulmonary Disease

University of Michigan

NCT00281242

COMPLETED Phase 4 30 participants

Peripheral Nerve Blocks for Above-the-knee Amputations

University of Florida

NCT03404180

COMPLETED Phase 1 28 participants

A Study to Investigate the Safety and Pharmacokinetics of a Single Dose of GSK2256294 in Healthy Young Males and Elderly Subjects

GlaxoSmithKline

NCT02006537

COMPLETED Phase 1 23 participants

Transforming Psychotherapy for Chronically Ill Patients

US Department of Veterans Affairs

NCT00520429

COMPLETED Phase 2 23 participants

Cathelicidin and Vitamin D: Impact on Populations At-Risk and With COPD

University of North Carolina, Chapel Hill

NCT02464059

COMPLETED Phase 1 22 participants

Study to Evaluate the Safety, Tolerability and Pharmacokinetics of GSK2269557 Administered Via the ELLIPTA Dry Powder Inhaler to Healthy Subjects

GlaxoSmithKline

NCT02691325

COMPLETED Phase 4 21 participants

Tolerability of Metoprolol-Succinate-ER and Carvedilol in COPD

VA Greater Los Angeles Healthcare System

NCT03370835

COMPLETED 21 participants

The Trajectory of Physical Activity Following Pulmonary Rehabilitation

Trinity Health Of New England

NCT02399254

COMPLETED Phase 1 20 participants

A Study to Evaluate the Effect of Itraconazole on the Pharmacokinetics (PK) of Nemiralisib

GlaxoSmithKline

NCT03398421

COMPLETED Phase 1 17 participants

Real-Time Support for Exercise Persistence in COPD

University of Washington

NCT00373932

COMPLETED NA 11 participants

Oxygen Savings With Administered Oxygen and High Flow Ambient Air At Rest

Johns Hopkins University

NCT04170062

COMPLETED NA 7 participants

Abdominal Functional Electrical Stimulation to Reduce Hyperinflation in Chronic Obstructive Pulmonary Disease Patients

Liberate Medical

NCT02035228

COMPLETED NA 6 participants

Home COPD and Open Ventilation Evaluation (HOPE) Study

Landon Pediatric Foundation

NCT03691181

COMPLETED Phase 2 5 participants

Proof of Concept Study Assessing Technology-Assisted Respiratory Adherence Prototype Version 3 in Individuals With COPD

Boehringer Ingelheim

NCT04795323

← Previous Page 2 of 2

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 13
Phase 3 22
Phase 4 12

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Pulmonary Disease, Chronic Obstructive Trial Landscape

75 indexed Pulmonary Disease, Chronic Obstructive studies · 7 recruiting (9%).

Phase mix: 34 late (III/IV) vs 20 early (I/II).

Top sponsor: GlaxoSmithKline (30 trials), 9 others listed. 25 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Pulmonary Disease, Chronic Obstructive?

PlainTrial tracks 75 US clinical trials for Pulmonary Disease, Chronic Obstructive, of which 7 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Pulmonary Disease, Chronic Obstructive?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.