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NCT03370835 · ClinicalTrials.gov registry record · Phase 4

Tolerability of Metoprolol-Succinate-ER and Carvedilol in COPD

A Phase 4 study of Asthma and Pulmonary Disease, Chronic Obstructive, sponsored by VA Greater Los Angeles Healthcare System.

Completed
Registry status
Phase 4
Development phase
21
Enrollment target
1
Study location

NCT03370835 is a Phase 4 study of Asthma and Pulmonary Disease, Chronic Obstructive that has completed, run by VA Greater Los Angeles Healthcare System. The registered enrollment target is 21 participants, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT03370835, a Phase 4 study of Asthma and Pulmonary Disease, Chronic Obstructive, has completed, sponsored by VA Greater Los Angeles Healthcare System.

COMPLETED
Registry status
Phase 4
Development phase
21 participants
Enrollment target
1
Study location

Study Summary

Use of beta-blockers has proven beneficial in patients with hypertension, heart failure, and in people who have suffered a heart attack. The use in patients who have Chronic Obstructive Pulmonary Disease (COPD) and reactive airway disease, however, has been limited due to possible side effects such as worsening of lung function or increasing airway spasms and asthma attacks. The purpose of this study is to find out if patients with COPD can tolerate being on a beta-blocker at doses recommended for the treatment of heart disease conditions. This study also seeks to find out if a selective beta-1 receptor beta-blocker is better than a non-selective beta-blocker in patients with mild to moderate COPD.

Interventions

  • DRUG Carvedilol
  • DRUG Metoprolol succinate ER

Study Locations (1)

California

  • VA West Los Angeles Medical Center - Los Angeles

Trial Details

FieldValue
Enrollment Target 21 participants
Start Date 2004-06
Est. Completion 2008-06
Phase Phase 4

What the Registry Record Tells You About NCT03370835

The ClinicalTrials.gov registry entry for NCT03370835 describes a study currently listed as completed, categorized as Phase 4. The registered enrollment target is 21 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 1,563-participant average among 374 other Asthma trials with a reported enrollment target (99% lower). The listed sponsor is VA Greater Los Angeles Healthcare System, which has 23 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Asthma appearing as the primary indexed condition, and to 2 interventions - of which Carvedilol is the first listed.

NCT03370835 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT03370835 about?

NCT03370835 is a clinical study titled "Tolerability of Metoprolol-Succinate-ER and Carvedilol in COPD". Use of beta-blockers has proven beneficial in patients with hypertension, heart failure, and in people who have suffered a heart attack. The use in patients who have Chronic Obstructive Pulmonary Disease (COPD) and reactive airway disease, however, has been limited due to possible side effects such ...

What is the current status of trial NCT03370835?

This trial is currently completed. It is a Phase 4 study. The enrollment target is 21 participants. The study started on 2004-06. Estimated completion is 2008-06.

What conditions does trial NCT03370835 study?

This clinical trial studies the following conditions: Asthma, Pulmonary Disease, Chronic Obstructive, Adverse Effect of Beta-adrenoreceptor Antagonists.

What interventions are being tested in trial NCT03370835?

The interventions under investigation include: Carvedilol (DRUG), Metoprolol succinate ER (DRUG).

Who is sponsoring clinical trial NCT03370835?

This trial is sponsored by VA Greater Los Angeles Healthcare System, which has 23 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT03370835 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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