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ClinicalTrials.gov 275 recruiting now early-phase tilt #4 of 28,963 conditions

Prostate Cancer: early-phase trial registry

275 of 749 indexed Prostate Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #4 of 28,963 conditions by registered trial count.

749 US clinical trials · 275 currently recruiting · #4 of 28,963 conditions by registered trial count

Prostate Cancer: 749 US clinical trials tracked, 275 recruiting.

Prostate Cancer is the subject of 749 registered US clinical trials on ClinicalTrials.gov, 275 of them currently open to new participants. 75 are in Phase 3-4 (later-stage) and 344 in Phase 1-2 (earlier-stage). The most active sponsor is Memorial Sloan Kettering Cancer Center, running 53 of these trials.

Open enrollment, early-phase tilt

Prostate Cancer has 749 registered US clinical trials, 275 of them open to new participants right now, about 37% of the total.

275
recruiting participants now
37%
of trials open to enrollment
75
in Phase 3-4 (later-stage)
53
top sponsor: Memorial Sloan Kettering Cancer Center

Corpus placement: #4 of 28,963 conditions by registered trial count on ClinicalTrials.gov-derived indexes. Registry reference only, not medical advice.

Key findings

What ClinicalTrials.gov does not surface for Prostate Cancer on its own pages , computed from the registry mirror as of 2026-07-11. Each line carries its own denominator so it can be quoted as it stands.

  1. Prostate Cancer recruits in line with its size-band peers.

    275 of 749 indexed trials (36.7%) are open to enrollment, against a 37.2% average across 135 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Prostate Cancer trials is spread across many organizations.

    Memorial Sloan Kettering Cancer Center accounts for 53 of 749 trials (7.1%). 283 distinct sponsors appear on at least one study for this condition label.

  3. Typical Prostate Cancer enrolment sits around 82 participants.

    Median target enrolment is 82 among the 736 trials that report a genuine target (sentinel values excluded). 389 of those (52.9%) plan for fewer than 100 participants.

  4. Prostate Cancer research is mostly interventional.

    628 interventional and 121 observational studies make up this index (83.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 1156Phase 2188Phase 362Phase 413

Open and recent trials

749 total, page 12 of 15

COMPLETED NA 92 participants

Using Virtual Reality (VR) Models for Robotic Prostatectomy

Ceevra

NCT03943368

COMPLETED NA 84 participants

Improving Outcomes in Cancer Patients on Oral Anti-Cancer Medications Using a Multi-modal Mobile Health Intervention

Massachusetts General Hospital

NCT02375776

COMPLETED Phase 2 82 participants

Docetaxel and Prednisone With/Out OGX-011 in Recurrent or Metastatic Prostate Cancer That Did Not Respond to Previous Hormone Therapy

NCIC Clinical Trials Group

NCT00258388

COMPLETED Phase 2 81 participants

Multicenter Trial of Abiraterone Acetate With or Without Cabazitaxel in Treatment of Metastatic Castration Resistant Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT02218606

COMPLETED Phase 2 80 participants

Radiation Therapy, Androgen Suppression, and Docetaxel in Treating Patients With High-Risk Prostate Cancer Who Have Undergone Radical Prostatectomy

Radiation Therapy Oncology Group

NCT00528866

COMPLETED Phase 1 80 participants

Dose Escalation and Efficacy Trial of GVAX® Prostate Cancer Vaccine

Cell Genesys

NCT00140348

COMPLETED Phase 2 80 participants

Docetaxel, Estramustine, and Exisulind in Treating Patients With Metastatic Prostate Cancer That Has Not Responded to Hormone Therapy

Alliance for Clinical Trials in Oncology

NCT00052845

COMPLETED 80 participants

Using PROMIS as Part of Routine Clinical Care for Racially Diverse Prostate and Bladder Cancer Patients

UNC Lineberger Comprehensive Cancer Center

NCT03156244

COMPLETED NA 79 participants

Isoflavones & Lycopene in Localized Prostate Ca:Prior to Radical Prostatectomy

H. Lee Moffitt Cancer Center and Research Institute

NCT00042731

COMPLETED Phase 1 79 participants

Reiki/Energy Healing in Prostate Cancer

The Cleveland Clinic

NCT00065208

COMPLETED Phase 1 77 participants

Study of 2 Different Doses of Revlimid in Biochemically Relapse Prostate Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT00348595

COMPLETED Phase 2 77 participants

Study of the Effect of GTx-758 on Serum PSA and Testosterone in Men With Prostate Cancer

GTx

NCT01615120

COMPLETED Phase 1 77 participants

Clinical and Molecular Correlates of Positron Emission Tomography (PET) With 89Zr-DFO-huJ591 in Metastatic Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT01543659

COMPLETED Phase 2 76 participants

Intramuscular Injections of Degarelix Administered in 1-Month Dosing Regimens in Patients With Prostate Cancer

Ferring Pharmaceuticals

NCT01491971

COMPLETED Phase 1 76 participants

Safety and Efficacy Study of AT-101 in Combination With Docetaxel and Prednisone in Men With HRPC

Ascenta Therapeutics

NCT00286793

COMPLETED Phase 2 76 participants

Safety and Tolerability of ODM-201 in Castrate Resistant Prostate Cancer; Extension Study to Study 3104001

Orion Corporation, Orion Pharma

NCT01429064

COMPLETED NA 75 participants

The "PC-LIGHT" Study

Northwestern University

NCT03419585

COMPLETED Phase 2 74 participants

Docetaxel and PROSTVAC for Metastatic Castration-Sensitive Prostate Cancer

National Cancer Institute (NCI)

NCT02649855

COMPLETED Phase 1 73 participants

A Bioequivalence Study Between the Proposed and Current Talazoparib Capsule Formulation and Food Effect Study for the Proposed Talazoparib Capsule Formulation in Participants With Advanced Solid Tumors

Pfizer

NCT04672460

COMPLETED 68 participants

A Feasibility Study Followed By A Randomized Phase II Study Of Yoga For Radiation Therapy Side Effects In Prostate Cancer

Abramson Cancer Center at Penn Medicine

NCT02135653

COMPLETED 67 participants

Development of a Clinical Trial Specific Question Prompt List

Memorial Sloan Kettering Cancer Center

NCT00662324

COMPLETED 66 participants

Effect of Radiotherapy Variables on Circulating Effectors of Immune Response and Local Microbiome

Weill Medical College of Cornell University

NCT03383107

COMPLETED Phase 2 64 participants

Vaccine Therapy With PROSTVAC/TRICOM and Flutamide Versus Flutamide Alone to Treat Prostate Cancer

National Cancer Institute (NCI)

NCT00450463

COMPLETED Phase 2 63 participants

Flutamide In the Prevention of Prostate Cancer in Patients With Neoplasia of the Prostate

Alliance for Clinical Trials in Oncology

NCT00006214

COMPLETED Phase 2 63 participants

Androgen Suppression Plus Radiation Therapy in Treating Patients With Prostate Cancer

Alliance for Clinical Trials in Oncology

NCT00006359

COMPLETED Phase 2 62 participants

Cabozantinib and Androgen Ablation in Patients With Androgen-Dependent Metastatic Prostate Cancer

M.D. Anderson Cancer Center

NCT01630590

COMPLETED 61 participants

Cancer DNA Detection in Blood and Urine

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT02657863

COMPLETED Phase 2 60 participants

Doxercalciferol Before Surgery in Treating Localized Prostate Cancer

University of Wisconsin, Madison

NCT00022412

COMPLETED NA 60 participants

Stereotactic Body Radiotherapy (SBRT) for Prostate Cancer

Duke University

NCT00941915

COMPLETED Phase 2 60 participants

Zoledronic Acid to Prevent Bone Loss During Androgen Deprivation Therapy for Prostate Cancer

Massachusetts General Hospital

NCT00181584

COMPLETED Phase 2 60 participants

PSA Vaccine Therapy in Treating Patients With Advanced Prostate Cancer

Eastern Cooperative Oncology Group

NCT00003871

COMPLETED Phase 2 59 participants

Metformin Prostate Cancer Adjuvant Trial

NYU Langone Health

NCT02176161

COMPLETED Phase 2 59 participants

AZD2171 to Treat Prostate Cancer

National Cancer Institute (NCI)

NCT00436956

COMPLETED NA 58 participants

Eating, Activity, and Stress Education

University of South Carolina

NCT01434004

COMPLETED 58 participants

Sodium Fluoride (NaF) Positron Emission Tomography/Computed Tomography (PET/CT) in Patients With Metastatic Castrate-resistant Prostate Cancer (CRPC) With Microtubule Directed Chemo or AR-directed Therapy

University of Wisconsin, Madison

NCT01516866

COMPLETED NA 57 participants

Embr Thermal Device for Hot Flash Management in Prostate Cancer

Embr Labs

NCT04892914

COMPLETED Phase 2 56 participants

Phase II Trial of Abraxane in Front Line Therapy of Hormone Refractory Metastatic Prostate Cancer

Kaiser Permanente

NCT00284752

COMPLETED Phase 2 56 participants

Hypofractionation Proton Beam Therapy With Concurrent Treatment of Prostate and Pelvic Nodes for Prostate Cancer

Mayo Clinic

NCT02874014

COMPLETED Phase 4 55 participants

Intrapatient Comparison of Urinary Radioactivity Following Piflufolastat (18F) and Flotufolastat (18F) PET in Men With Low PSA Biochemical Recurrence of Prostate Cancer Following Radical Prostatectomy

Blue Earth Diagnostics

NCT06604442

COMPLETED Phase 1 55 participants

Radioimmunotherapy in Prostate Cancer Using 177Lu-J591 Antibody

Weill Medical College of Cornell University

NCT00538668

COMPLETED Phase 2 53 participants

ZK-Epo Given With Prednisone in Patients With Metastatic Androgen-independent Prostate Cancer

Bayer

NCT00350051

COMPLETED Phase 2 52 participants

The Specific Role of Isoflavones in Reducing Prostate Cancer Risk

H. Lee Moffitt Cancer Center and Research Institute

NCT00617617

COMPLETED NA 52 participants

Impact of Catheter Size on Peri-Operative Pain After Robotic Assisted Laparoscopic Prostatectomy

Benaroya Research Institute

NCT04098809

COMPLETED Phase 2 51 participants

The Role of 68Ga-PSMA-11 PET (Prostate Specific Membrane Antigen) in Surgery Guidance in Prostate Cancer

Clinton Bahler

NCT04936334

COMPLETED NA 50 participants

Dual-Tracer Theranostic PET

University of Utah

NCT05680675

COMPLETED NA 50 participants

Sleep, Exercise, Nutrition and Survivorship in Prostate Cancer

NYU Langone Health

NCT05318131

COMPLETED Phase 4 50 participants

Effect Of Risedronate On Bone Mass In Older Men Receiving Neoadjuvant Therapy For Prostate Cancer

UConn Health

NCT00859027

COMPLETED Phase 1 50 participants

ADXS31-142 Alone and in Combination With Pembrolizumab (MK-3475) in Participants With Previously Treated Metastatic Castration-Resistant Prostate Cancer (mCRPC)

Advaxis

NCT02325557

COMPLETED NA 50 participants

Acupuncture Treatment for Hot Flashes Study

New York Presbyterian Brooklyn Methodist Hospital

NCT00421902

COMPLETED Phase 2 50 participants

ET 743 (Yondelis) in Men With Advanced Prostate Cancer

Massachusetts General Hospital

NCT00147212

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Phase Distribution

PhaseTrial count
Phase 1 156
Phase 2 188
Phase 3 62
Phase 4 13

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What is open for Prostate Cancer right now

275 recruiting of 749 indexed (37% open).

Phase mix: 75 late (III/IV) vs 344 early (I/II) (early-phase heavy).

Top sponsor: Memorial Sloan Kettering Cancer Center (53 trials), 9 others listed. 50 shown below, recruiting first. #4 of 28,963 conditions by registered trial count.

How open-enrollment share is computed

Open share is recruiting_count divided by trial_count for this condition label in the public registry export. Status can change between pulls; treat the figure as a snapshot of research attention, not treatment availability.

Frequently Asked Questions

How many clinical trials are there for Prostate Cancer?

PlainTrial tracks 749 US clinical trials for Prostate Cancer, of which 275 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Prostate Cancer?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.