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ClinicalTrials.gov 10 recruiting now official registry

Prostate Cancer Metastatic clinical trials

10 of 18 indexed Prostate Cancer Metastatic trials are currently recruiting.

18 US clinical trials · 10 currently recruiting

Prostate Cancer Metastatic is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Orion Corporation, Orion Pharma, running 1 of these trials.

The research picture

Prostate Cancer Metastatic has 18 registered US clinical trials, 10 of them open to new participants right now, about 56% of the total.

10
recruiting participants now
56%
of trials open to enrollment
2
in Phase 3–4 (later-stage)
1
top sponsor: Orion Corporation, Orion Pharma
Phase 13Phase 26Phase 32

Active & Recent Trials

18 total, page 1 of 1

RECRUITING Phase 3 1,310 participants

Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

Merck Sharp & Dohme

NCT06136624

RECRUITING Phase 2 130 participants

Evaluation of Response to Abiraterone/Prednisone by Race/Ethnicity and Other Factors in Metastatic Hormone Naive Prostate Cancer

Martha Mims

NCT03833921

RECRUITING 120 participants

ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials

Duke University

NCT06141993

RECRUITING 120 participants

Geriatric Assessment and Technology Evaluation in Prostate Cancer

University of Chicago

NCT06215508

RECRUITING NA 80 participants

Tumor Genomic Pre-test Counseling Tool for Black or African-American Men With Prostate Cancer

University of California, San Francisco

NCT06171139

RECRUITING NA 62 participants

Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy

Dana-Farber Cancer Institute

NCT05327465

RECRUITING Phase 2 60 participants

Castrate Resistant Prostate Cancer Enhertu Therapy

Washington D.C. Veterans Affairs Medical Center

NCT06610825

RECRUITING 30 participants

FTT PET/CT in Metastatic Prostate Cancer

Abramson Cancer Center at Penn Medicine

NCT05242744

RECRUITING Phase 2 30 participants

Treatment of Patients With Progressive mCRPC With 177Lu-PSMA-617

Ebrahim S Delpassand

NCT06972628

RECRUITING NA 20 participants

Exercise in Prostate Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT06165302

ACTIVE NOT RECRUITING Phase 1 204 participants

Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant Prostate Cancer

Orion Corporation, Orion Pharma

NCT03436485

ACTIVE NOT RECRUITING Phase 1 152 participants

A Study of ARV-766 Given by Mouth in Men With Metastatic Prostate Cancer

Novartis Pharmaceuticals

NCT05067140

ACTIVE NOT RECRUITING Phase 2 111 participants

Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamide

Alliance Foundation Trials

NCT04335682

ACTIVE NOT RECRUITING 58 participants

Prostate-Specific Membrane Antigen (PSMA) PET Scans in People Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT04030338

ACTIVE NOT RECRUITING Phase 2 45 participants

Pembrolizumab and Lenvatinib in Advanced/Metastatic Neuroendocrine Prostate Cancer

University of Michigan Rogel Cancer Center

NCT04848337

ACTIVE NOT RECRUITING Phase 2 26 participants

REGN2810 Followed by Chemoimmunotherapy for Newly Metastatic Hormone-sensitive Prostate Cancer

Mark Stein

NCT03951831

ACTIVE NOT RECRUITING Phase 1 16 participants

Phase I Trial of Apalutamide Plus Abiraterone Acetate, Docetaxel, and Prednisone in Patients With mCRPC

Weill Medical College of Cornell University

NCT02913196

COMPLETED Phase 3 1,297 participants

A Randomized, Double-blind, Phase 3 Efficacy Trial of PROSTVAC-V/F +/- GM-CSF in Men With Asymptomatic or Minimally Symptomatic Metastatic Castrate-Resistant Prostate Cancer

Bavarian Nordic

NCT01322490

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 6
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Prostate Cancer Metastatic Trial Landscape

18 indexed Prostate Cancer Metastatic studies · 10 recruiting (56%).

Phase mix: 2 late (III/IV) vs 9 early (I/II).

Top sponsor: Orion Corporation, Orion Pharma (1 trial), 9 others listed. 18 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Prostate Cancer Metastatic?

PlainTrial tracks 18 US clinical trials for Prostate Cancer Metastatic, of which 10 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Prostate Cancer Metastatic?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.