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ClinicalTrials.gov 10 recruiting now early-phase tilt small index

Prostate Cancer Metastatic: early-phase trial registry

10 of 18 indexed Prostate Cancer Metastatic trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #953 of 28,707 conditions by registered trial count.

18 US clinical trials · 10 currently recruiting · #953 of 28,707 conditions by registered trial count

Prostate Cancer Metastatic: 18 US clinical trials tracked, 10 recruiting.

Prostate Cancer Metastatic is the subject of 18 registered US clinical trials on ClinicalTrials.gov, 10 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Orion Corporation, Orion Pharma, running 1 of these trials.

Enrollment posture brief

Registry condition prostate-cancer-metastatic

OPEN 10 | RECR 56% | LATE 2 | EARLY 9 | RANK #953 | SPON 1

Nearest open-share peer: Acute Lymphoblastic Leukemia, Pediatric (56% recruiting · 9 trials)

Prostate Cancer Metastat (th…56%Arrhythmias, Cardiac27.8%Androgenetic Alopecia16.7%Anemia, Sickle Cell16.7%Acquired Immunodeficiency Sy5.6%
Open-enrollment share among volume-matched conditions near Prostate Cancer Metastatic

Prostate Cancer Metastatic lists 10 open slots (56% of 18 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Prostate Cancer Metastatic on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Prostate Cancer Metastatic is recruiting above its size-band peers.

    10 of 18 indexed trials (55.6%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Prostate Cancer Metastatic trials is spread across many organizations.

    Orion Corporation, Orion Pharma accounts for 1 of 18 trials (5.6%). 18 distinct sponsors appear on at least one study for this condition label.

  3. Typical Prostate Cancer Metastatic enrolment sits around 80 participants.

    Median target enrolment is 80 among the 18 trials that report a genuine target (sentinel values excluded). 10 of those (55.6%) plan for fewer than 100 participants.

  4. Prostate Cancer Metastatic research is mostly interventional.

    14 interventional and 4 observational studies make up this index (77.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 26Phase 32

Open and recent trials

18 total, page 1 of 1

RECRUITING Phase 3 1,310 participants

Study of Opevesostat (MK-5684) Versus Alternative NHA in mCRPC (MK-5684-003)

Merck Sharp & Dohme

NCT06136624

RECRUITING Phase 2 130 participants

Evaluation of Response to Abiraterone/Prednisone by Race/Ethnicity and Other Factors in Metastatic Hormone Naive Prostate Cancer

Martha Mims

NCT03833921

RECRUITING 120 participants

ARCTIC: Liquid Biomarkers in the Prospective Androgen Receptor Signaling Inhibitors (ARSI) Resistance Clinical Trials

Duke University

NCT06141993

RECRUITING 120 participants

Geriatric Assessment and Technology Evaluation in Prostate Cancer

University of Chicago

NCT06215508

RECRUITING NA 80 participants

Tumor Genomic Pre-test Counseling Tool for Black or African-American Men With Prostate Cancer

University of California, San Francisco

NCT06171139

RECRUITING NA 62 participants

Exercise to Enhance Cardiovascular Health Among Black Prostate Cancer Patients With Androgen Deprivation Therapy

Dana-Farber Cancer Institute

NCT05327465

RECRUITING Phase 2 60 participants

Castrate Resistant Prostate Cancer Enhertu Therapy

Washington D.C. Veterans Affairs Medical Center

NCT06610825

RECRUITING 30 participants

FTT PET/CT in Metastatic Prostate Cancer

Abramson Cancer Center at Penn Medicine

NCT05242744

RECRUITING Phase 2 30 participants

Treatment of Patients With Progressive mCRPC With 177Lu-PSMA-617

Ebrahim S Delpassand

NCT06972628

RECRUITING NA 20 participants

Exercise in Prostate Cancer

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT06165302

ACTIVE NOT RECRUITING Phase 1 204 participants

Safety and Pharmacokinetics of ODM-208 in Patients With Metastatic Castration-resistant Prostate Cancer

Orion Corporation, Orion Pharma

NCT03436485

ACTIVE NOT RECRUITING Phase 1 152 participants

A Study of ARV-766 Given by Mouth in Men With Metastatic Prostate Cancer

Novartis Pharmaceuticals

NCT05067140

ACTIVE NOT RECRUITING Phase 2 111 participants

Androgen Receptor Directed Therapy on Cognitive Function in Patients Treated With Darolutamide or Enzalutamide

Alliance Foundation Trials

NCT04335682

ACTIVE NOT RECRUITING 58 participants

Prostate-Specific Membrane Antigen (PSMA) PET Scans in People Prostate Cancer

Memorial Sloan Kettering Cancer Center

NCT04030338

ACTIVE NOT RECRUITING Phase 2 45 participants

Pembrolizumab and Lenvatinib in Advanced/Metastatic Neuroendocrine Prostate Cancer

University of Michigan Rogel Cancer Center

NCT04848337

ACTIVE NOT RECRUITING Phase 2 26 participants

REGN2810 Followed by Chemoimmunotherapy for Newly Metastatic Hormone-sensitive Prostate Cancer

Mark Stein

NCT03951831

ACTIVE NOT RECRUITING Phase 1 16 participants

Phase I Trial of Apalutamide Plus Abiraterone Acetate, Docetaxel, and Prednisone in Patients With mCRPC

Weill Medical College of Cornell University

NCT02913196

COMPLETED Phase 3 1,297 participants

A Randomized, Double-blind, Phase 3 Efficacy Trial of PROSTVAC-V/F +/- GM-CSF in Men With Asymptomatic or Minimally Symptomatic Metastatic Castrate-Resistant Prostate Cancer

Bavarian Nordic

NCT01322490

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 6
Phase 3 2

Named interventions

Most-linked intervention names on Prostate Cancer Metastatic records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Abiraterone acetate Drug
2 trials
Questionnaires Other
2 trials
Enzalutamide Drug
2 trials
Prednisone Drug
2 trials
Docetaxel Drug
2 trials
GM-CSF Placebo Other
1 trials
PROSTVAC-F Biological
1 trials
PROSTVAC-V Biological
1 trials

US sites by state

Facility locations filed on Prostate Cancer Metastatic trials. A trial with sites in several states counts in each.

New York 6 trials
California 6 trials
Maryland 4 trials
Illinois 4 trials
Wisconsin 3 trials
Texas 3 trials
Minnesota 3 trials
Michigan 3 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Prostate Cancer Metastatic page

18 registered trials, 10 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Prostate Cancer Metastatic condition card totals 18 registered trials; most-linked intervention Abiraterone acetate; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.