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NCT01322490 · ClinicalTrials.gov registry record · Phase 3

A Randomized, Double-blind, Phase 3 Efficacy Trial of PROSTVAC-V/F +/- GM-CSF in Men With Asymptomatic or Minimally Symptomatic Metastatic Castrate-Resistant Prostate Cancer

A Phase 3 study of Prostate Cancer Metastatic, sponsored by Bavarian Nordic.

Completed
Registry status
Phase 3
Development phase
1,297
Enrollment target
20
Study locations

NCT01322490 is a Phase 3 study of Prostate Cancer Metastatic that has completed, run by Bavarian Nordic. The registered enrollment target is 1,297 participants, above the 151-participant average among 17 other Prostate Cancer Metastatic trials with a reported enrollment target (759% higher). The trial reports 20 study locations across 6 states.

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The verdict

NCT01322490, a Phase 3 study of Prostate Cancer Metastatic, has completed, sponsored by Bavarian Nordic.

COMPLETED
Registry status
Phase 3
Development phase
1,297 participants
Enrollment target
20
Study locations

Study Summary

The purpose of this study is to determine whether PROSTVAC alone or in combination with GM-CSF is effective in prolonging overall survival in men with few or no symptoms from metastatic, castrate-resistant prostate cancer.

Conditions Studied

Interventions

  • BIOLOGICAL Placebo
  • DRUG GM-CSF
  • BIOLOGICAL PROSTVAC-V
  • BIOLOGICAL PROSTVAC-F
  • OTHER GM-CSF Placebo

Study Locations (20)

California

  • Alta Bates Summit Medical Center - Berkeley
  • Cedars-Sinai Medical Center - Los Angeles
  • Prostate Oncology Specialists, Inc. - Marina del Rey
  • Desert Hematology-Oncology - Rancho Mirage
  • San Bernardino Urological Associates - San Bernardino
  • San Diego Clinical Trials - San Diego
  • Sharp Memorial Hospital - San Diego
  • VA San Diego Healthcare System - San Diego
  • Stanford Advanced Medical Center - Stanford

Florida

  • South Florida Medical Research - Aventura
  • Manatee Medical Research Institute, LLC - Bradenton
  • Florida Urology Physicians - Fort Myers
  • Lakeland Regional Cancer Center - Lakeland
  • Pinellas Urology, Inc. - St. Petersburg
  • James A Haley Veteran Affairs Medical Center - Tampa

Colorado

  • University of Colorado - Aurora
  • The Urology Center of Colorado - Denver

Alaska

  • Alaska Clinical Research Center, Llc - Anchorage

Arizona

  • Scottsdale Healthcare - Scottsdale

District of Columbia

  • Washington Cancer Institute - Washington D.C.

Trial Details

FieldValue
Enrollment Target 1,297 participants
Start Date 2011-11-28
Est. Completion 2017-12-15
Phase Phase 3

Sponsor

Bavarian Nordic

41 total trials

What the Registry Record Tells You About NCT01322490

The ClinicalTrials.gov registry entry for NCT01322490 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 1,297 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 151-participant average among 17 other Prostate Cancer Metastatic trials with a reported enrollment target (759% higher). The listed sponsor is Bavarian Nordic, which has 41 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Prostate Cancer Metastatic appearing as the primary indexed condition, and to 5 interventions - of which Placebo is the first listed.

NCT01322490 reports 20 study locations spanning 6 distinct geographic areas - top geographies include California, Florida, Colorado.

Frequently Asked Questions

What is clinical trial NCT01322490 about?

NCT01322490 is a clinical study titled "A Randomized, Double-blind, Phase 3 Efficacy Trial of PROSTVAC-V/F +/- GM-CSF in Men With Asymptomatic or Minimally Symptomatic Metastatic Castrate-Resistant Prostate Cancer". The purpose of this study is to determine whether PROSTVAC alone or in combination with GM-CSF is effective in prolonging overall survival in men with few or no symptoms from metastatic, castrate-resistant prostate cancer.

What is the current status of trial NCT01322490?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 1,297 participants. The study started on 2011-11-28. Estimated completion is 2017-12-15.

What conditions does trial NCT01322490 study?

This clinical trial studies the following conditions: Prostate Cancer Metastatic.

What interventions are being tested in trial NCT01322490?

The interventions under investigation include: Placebo (BIOLOGICAL), GM-CSF (DRUG), PROSTVAC-V (BIOLOGICAL), PROSTVAC-F (BIOLOGICAL), GM-CSF Placebo (OTHER).

Who is sponsoring clinical trial NCT01322490?

This trial is sponsored by Bavarian Nordic, which has 41 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT01322490 being conducted?

This trial has 20 study locations across Alaska, Arizona, California, Colorado, District of Columbia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.