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A Study of ARV-766 Given by Mouth in Men With Metastatic Prostate Cancer
NCT05067140 · View on ClinicalTrials.gov ↗
Study Summary
A Phase 1/2 study to evaluate the safety and efficacy of ARV-766 given by mouth alone or in combination with abiraterone in men with metastatic prostate cancer.
Conditions Studied
Interventions
- DRUG ARV-766 Part A&B
- DRUG ARV-766 + Abiraterone Part C&D
Study Locations (20)
California
- Clinical Trial Site — Duarte
- Clinical Trial Site — Fresno
- Clinical Trial Site — La Jolla
- Clinical Trial Site — Orange
- Clinical Trial Site — Santa Monica
New York
- Clinical Trial Site — Buffalo
- Clinical Trial Site — New York
Pennsylvania
- Clinical Trial Site — Philadelphia
- Clinical Trial Site — Pittsburgh
Connecticut
- Clinical Trial Site — New Haven
District of Columbia
- Clinical Trial Site — Washington D.C.
Florida
- Clinical Trial Site — Lake Mary
Illinois
- Clinical Trial Site — Chicago
Louisiana
- Clinical Trial Site — New Orleans
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 152 participants |
| Start Date | 2021-09-02 |
| Est. Completion | 2027-05-25 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05067140
The ClinicalTrials.gov registry entry for NCT05067140 describes a study currently listed as active not recruiting. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 152 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Novartis Pharmaceuticals, which has 792 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Prostate Cancer Metastatic appearing as the primary indexed condition, and to 2 interventions — of which ARV-766 Part A&B is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05067140 reports 20 study locations spanning 14 distinct geographic areas — top geographies include California, New York, Pennsylvania. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05067140 about?
NCT05067140 is a clinical study titled "A Study of ARV-766 Given by Mouth in Men With Metastatic Prostate Cancer". A Phase 1/2 study to evaluate the safety and efficacy of ARV-766 given by mouth alone or in combination with abiraterone in men with metastatic prostate cancer.
What is the current status of trial NCT05067140?
This trial is currently active not recruiting. It is a Phase 1 study. The enrollment target is 152 participants. The study started on 2021-09-02. Estimated completion is 2027-05-25.
What conditions does trial NCT05067140 study?
This clinical trial studies the following conditions: Prostate Cancer Metastatic. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05067140?
The interventions under investigation include: ARV-766 Part A&B (DRUG), ARV-766 + Abiraterone Part C&D (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05067140?
This trial is sponsored by Novartis Pharmaceuticals, which has 792 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05067140 being conducted?
This trial has 20 study locations across California, Connecticut, District of Columbia, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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