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NCT06972628 · ClinicalTrials.gov registry record · Phase 2

Treatment of Patients With Progressive mCRPC With 177Lu-PSMA-617

A Phase 2 study of Prostate Cancer and Metastatic Castration-Resistant Prostate Cancer, sponsored by Ebrahim S Delpassand.

Recruiting
Registry status
Phase 2
Development phase
30
Enrollment target
1
Study location

NCT06972628 is a Phase 2 study of Prostate Cancer and Metastatic Castration-Resistant Prostate Cancer that is actively recruiting participants, run by Ebrahim S Delpassand. The registered enrollment target is 30 participants, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (95% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT06972628, a Phase 2 study of Prostate Cancer and Metastatic Castration-Resistant Prostate Cancer, is actively recruiting participants, sponsored by Ebrahim S Delpassand.

RECRUITING
Registry status
Phase 2
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to evaluate the safety and tolerability of Lutetium-177-PSMA-617 (PLUVICTO) in patients with metastatic castration-resistant prostate cancer (mCRPC) and extensive bone metastases, which appear as a "super scan" pattern on a bone scan. Pluvicto is FDA-approved, but patients with super scan bone scans were previously excluded from the VISION clinical trial, leaving a knowledge gap. The study will enroll up to 30 men with metastatic castration-resistant prostate cancer, with an initial dosing approach that differs from the standard dose. The safety and tolerability of PLUVICTO will be evaluated in this study, with a focus on identifying the optimal dose for this population. This study addresses an important gap in understanding how Pluvicto performs in mCRPC patients with super scan findings.

Interventions

  • DRUG Administering Lutetium-177-PSMA-617 (PLUVICTO)

Study Locations (1)

Texas

  • Excel Diagnostics & Nuclear Oncology Center - Houston

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2025-05-23
Est. Completion 2029-04-01
Phase Phase 2

Sponsor

Ebrahim S Delpassand

2 total trials

What the Registry Record Tells You About NCT06972628

The ClinicalTrials.gov registry entry for NCT06972628 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 608-participant average among 735 other Prostate Cancer trials with a reported enrollment target (95% lower). The listed sponsor is Ebrahim S Delpassand, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 5 conditions, with Prostate Cancer appearing as the primary indexed condition, and to 1 intervention - of which Administering Lutetium-177-PSMA-617 (PLUVICTO) is the first listed.

NCT06972628 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT06972628 about?

NCT06972628 is a clinical study titled "Treatment of Patients With Progressive mCRPC With 177Lu-PSMA-617". The purpose of this study is to evaluate the safety and tolerability of Lutetium-177-PSMA-617 (PLUVICTO) in patients with metastatic castration-resistant prostate cancer (mCRPC) and extensive bone metastases, which appear as a "super scan" pattern on a bone scan. Pluvicto is FDA-approved, but patie...

What is the current status of trial NCT06972628?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 30 participants. The study started on 2025-05-23. Estimated completion is 2029-04-01.

What conditions does trial NCT06972628 study?

This clinical trial studies the following conditions: Prostate Cancer, Metastatic Castration-Resistant Prostate Cancer, Prostate Cancer Metastatic, Prostate Cancer (CRPC), Prostate Cancer Patients With Bone Metastasis.

What interventions are being tested in trial NCT06972628?

The interventions under investigation include: Administering Lutetium-177-PSMA-617 (PLUVICTO) (DRUG).

Who is sponsoring clinical trial NCT06972628?

This trial is sponsored by Ebrahim S Delpassand, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT06972628 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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