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NCT01783288 · ClinicalTrials.gov registry record · NA
Aldosterone & Sodium Regulation in Postural Tachycardia Syndrome - Screening
A NA study of Postural Tachycardia Syndrome, sponsored by Vanderbilt University.
- Active
- Registry status
- NA
- Development phase
- 110
- Enrollment target
- 1
- Study location
NCT01783288: Active NA study of Postural Tachycardia Syndrome, sponsored by Vanderbilt University.
NCT01783288 is a NA study of Postural Tachycardia Syndrome that is active but no longer recruiting, run by Vanderbilt University. The registered enrollment target is 110 participants, above the 77-participant average among 19 other Postural Tachycardia Syndrome trials with a reported enrollment target (43% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01783288, a NA study of Postural Tachycardia Syndrome, is active but no longer recruiting, sponsored by Vanderbilt University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 110 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to determine whether patients meet criteria for Postural Tachycardia Syndrome (or not) and have reduced blood volume (or not). Both of these are important screening elements to Aim 3 of a National Institutes of Health Grant. The purposes of Aim 3 are to determine 1. whether a high dietary sodium level appropriately expands plasma volume in Postural Orthostatic Tachycardia, 2. whether plasma renin activity and aldosterone are modified appropriately by changes in dietary sodium in Postural Tachycardia Syndrome and 3. whether patients with Postural Tachycardia Syndrome have improvements in their orthostatic tachycardia and symptoms as a result of a high dietary sodium level.
Primary Outcome
Compare blood volume deviations using the 131-I-Albumin method. Deviations will be reported as a percentage deviation from an individual's predicted value. These values will be compared between POTS patients and healthy control groups.
Conditions Studied
Interventions
- OTHER Autonomic Function Testing
- OTHER Posture Study
- PROCEDURE Measurement of Total Blood Volume
- OTHER Exercise Capacity Test
Study Locations (1)
Tennessee
- Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 110 participants |
| Start Date | 2013-02 |
| Est. Completion | 2026-12 |
| Phase | NA |
What the registry record for NCT01783288 still lists
NCT01783288 is an interventional study that assigns participants to a tested intervention. The registered 110 participants enrollment target is mid-sized for trials with a published cap, above the 77-participant average among 19 other Postural Tachycardia Syndrome trials with a reported enrollment target (43% higher).
The record links to 1 condition, with Postural Tachycardia Syndrome appearing as the primary indexed condition, and to 4 interventions - of which Autonomic Function Testing is the first listed.
NCT01783288 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT01783288 about?
NCT01783288 is a clinical study titled "Aldosterone & Sodium Regulation in Postural Tachycardia Syndrome - Screening". The purpose of the study is to determine whether patients meet criteria for Postural Tachycardia Syndrome (or not) and have reduced blood volume (or not). Both of these are important screening elements to Aim 3 of a National Institutes of Health Grant. The purposes of Aim 3 are to determine 1. wheth...
What is the current status of trial NCT01783288?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 110 participants. The study started on 2013-02. Estimated completion is 2026-12.
What conditions does trial NCT01783288 study?
This clinical trial studies the following conditions: Postural Tachycardia Syndrome.
What interventions are being tested in trial NCT01783288?
The interventions under investigation include: Autonomic Function Testing (OTHER), Posture Study (OTHER), Measurement of Total Blood Volume (PROCEDURE), Exercise Capacity Test (OTHER).
Who is sponsoring clinical trial NCT01783288?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01783288 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Postural Tachycardia Syndrome
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01783288's enrollment target sits among peer trials
110 3rd of 19 higher than 17 of 19 other Postural Tachycardia Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postural Tachycardia Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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-
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ACTIVE NOT RECRUITING · NA
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