AtriCure

Open enrollment across a mixed-phase pipeline

According to ClinicalTrials.gov-derived indexes, AtriCure sits in the top decile of US sponsors by registered trial count (#668 of 15,742 sponsors by registered trial count).

23 total trials 5 currently recruiting 14 completed top decile by trial count

AtriCure: 23 sponsored US clinical trials, 5 recruiting.

AtriCure sponsors 23 registered US clinical trials on ClinicalTrials.gov, 5 of them currently recruiting, and 14 completed. 3 of these trials are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Atrial Fibrillation, with 3 trials.

Top-decile sponsor footprint

AtriCure ranks in the top decile of sponsors by registered trial count (#668 of 15,742 sponsors by registered trial count). Volume at this scale usually reflects a long institutional pipeline, read phase tilt and therapeutic areas below before treating it as current-year activity.

Trial completion reliability score

A 90/100

14 of 14 decided trials (Completed vs. Terminated on ClinicalTrials.gov) reached their planned completion (100.0%), vs. national p10 68.4% / p90 100% among 1,234 sponsors with at least 10 decided trials. Still-open trials (Recruiting, Active-not-recruiting, Not-yet-recruiting) are excluded since they have not reached an outcome yet.

Open and recent trials

23 total, page 1 of 1

RECRUITING NA

BoxX-NoAF Clinical Trial

NCT06989775

RECRUITING

Cryo NerVe Block Extremity AmputatioN RegIStry for Post Operative and pHantom Limb Pain

NCT06908538

RECRUITING

Inappropriate Sinus Tachycardia Registry

NCT05107635

RECRUITING

A Multicenter Patient Registry on Outcomes From Cryoanalgesia of the Intercostal Nerves

NCT05110989

RECRUITING

Tracking Results of Ablations to Combat AF Registry Generation 2

NCT05111015

ACTIVE NOT RECRUITING NA

Left Atrial Appendage Exclusion for Prophylactic Stroke Reduction Trial

NCT05478304

ACTIVE NOT RECRUITING NA

HEAL-IST IDE Trial

NCT05280093

ACTIVE NOT RECRUITING NA

CONVERGE Post-Approval Study (PAS)

NCT05393180

ACTIVE NOT RECRUITING NA

AtriCure CryoICE Lesions for Persistent and Long-standing Persistent Atrial Fibrillation Treatment

NCT03732794

COMPLETED

FREEZE-AFIB Post-Market Study

NCT05089877

COMPLETED NA

VCLIP Post-Market Study, Long-term Follow-up on LAA Exclusion Using AtriClip

NCT05101993

COMPLETED NA

aMAZE Trial Continued Access Protocol

NCT04468334

COMPLETED NA

The cryoICE™ CryoAnalgesia Study For Pain Management in Post thoRacic Procedures Via intercOSTal Cryoanalgesia (FROST)

NCT02922153

COMPLETED Phase 4

AtriClip® Left Atrial Appendage Exclusion Concomitant to Structural Heart Procedures (ATLAS)

NCT02701062

COMPLETED NA

Pivotal Study Of A Dual Epicardial & Endocardial Procedure (DEEP) Approach

NCT02393885

COMPLETED Phase 1

Stroke Feasibility Study

NCT01997905

COMPLETED NA

CONVERGE - Epi/Endo Ablation For Treatment of Persistent Atrial Fibrillation(AF)

NCT01984346

COMPLETED NA

ABLATE Post Approval Study - Synergy Ablation Lesions for Non-Paroxysmal Atrial Fibrillation

NCT01694563

COMPLETED NA

Dual Epicardial Endocardial Persistent Atrial Fibrillation(AF) Study (Staged DEEP)

NCT01661205

COMPLETED NA

Dual Epicardial Endocardial Persistent Atrial Fibrillation (AF) Study

NCT01246466

COMPLETED Phase 2

AtriCure Exclusion of the LAA in Patients Undergoing Concomitant Cardiac Surgery

NCT00779857

COMPLETED Phase 3

AtriCure Bipolar Radiofrequency Ablation of Permanent Atrial Fibrillation

NCT00560885

COMPLETED Phase 3

Concomitant Treatment of Permanent Atrial Fibrillation

NCT00566787

What is open in the AtriCure pipeline

5 recruiting of 23 indexed (22% open); 14 completed (61%).

Phase mix: 3 late (III/IV) vs 2 early (I/II) (balanced across stages).

Top condition: Atrial Fibrillation (3 trials), 9 others listed.

How open-pipeline share is computed

Recruiting share is recruiting_count divided by trial_count for this sponsor in the public registry export. Status can change between pulls; treat the figure as a research-attention snapshot, not product availability.

AtriCure: open-pipeline peers nationwide

Peers matched on 23 registered trials and 22% open enrollment, not the therapeutic-area sidebar.

AtriCure sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot). 2×2 strategic matrix plotting 9 entities by Total trials (X) and Recruiting share (Y), with a crosshair dividing the plot into four quadrants. Higher volume & more openFocused & more openHigher volume, mostly closedSmaller & mostly closed 0100200300 0%5%10%15%20%25% Total trials Recruiting share AtriCureAMAG PharmaceuticalsCara TherapeuticsCraig L Slingluff, JrDuramed ResearchUniversity of Colorado, BoulderUniversity of Maryland, College ParkRegeneron PharmaceuticalsHenry M. Jackson Foundation for the Advancement of Military Medicine
AtriCure sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together. Source: ClinicalTrials.gov (2026-08-08 snapshot).

AtriCure sits at or above the median trial volume and at or above the median recruiting share among these 9 nationwide peers -- the two do not always move together.

Sponsors near 23 trials (± recruiting share)

Sponsors near 22% open enrollment (± trial volume)

What to do with this AtriCure page

23 registered trials is a research-attention snapshot, not an endorsement of AtriCure or any single study.

  • 5 of AtriCure's trials are currently recruiting, check each one's own eligibility criteria before contacting a site. Browse recruiting trials
  • Atrial Fibrillation is the condition AtriCure studies most, compare against other sponsors active in the same condition before evaluating a specific study. See Atrial Fibrillation trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

AtriCure pipeline card: 23 registered trials from official public datasets.Report a data error.