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Postural Orthostatic Tachycardia Syndrome: full-pipeline trial registry
3 of 12 indexed Postural Orthostatic Tachycardia Syndrome trials are currently recruiting.
Corpus placement: #1,429 of 28,707 conditions by registered trial count.
12 US clinical trials · 3 currently recruiting · #1,429 of 28,707 conditions by registered trial count
Postural Orthostatic Tachycardia Syndrome: 12 US clinical trials tracked, 3 recruiting.
Postural Orthostatic Tachycardia Syndrome is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Vanderbilt University, running 2 of these trials.
Enrollment posture brief
Registry condition postural-orthostatic-tachycardia-syndrome
OPEN 3 | RECR 25% | LATE 1 | EARLY 1 | RANK #1429 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Abdominal Cancer (25% recruiting · 8 trials)
Postural Orthostatic Tachycardia Syndrome lists 3 open slots (25% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Postural Orthostatic Tachycardia Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Postural Orthostatic Tachycardia Syndrome is recruiting below its size-band peers.
3 of 12 indexed trials (25%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Postural Orthostatic Tachycardia Syndrome research.
Vanderbilt University accounts for 2 of 12 trials (16.7%). 10 distinct sponsors appear on at least one study for this condition label.
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Most Postural Orthostatic Tachycardia Syndrome trials plan to enrol fewer than 100 people.
Median target enrolment is 70 among the 12 trials that report a genuine target (sentinel values excluded). 8 of those (66.7%) plan for fewer than 100 participants.
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Postural Orthostatic Tachycardia Syndrome research is mostly interventional.
9 interventional and 3 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
12 total, page 1 of 1
The Long COVID-19 Wearable Device Study
Scripps Translational Science Institute
NCT05741112
Phenotyping of Postural Orthostatic Tachycardia Syndrome (POTS)
University of Texas Southwestern Medical Center
NCT06292104
Auricular Vagal Nerve Stimulation for Hypermobile Ehlers-Danlos Syndrome
Medical College of Wisconsin
NCT05212129
Pathophysiology of Orthostatic Intolerance
Satish R. Raj
NCT00608725
Assessment of Antibodies and Inflammatory Markers in Postural Tachycardia Syndrome
Vanderbilt University
NCT02196376
Evaluating the Prevalence of Acute Hepatic Porphyria in Postural Tachycardia Syndrome
Vanderbilt University Medical Center
NCT05344599
Breathing Device in Postural Orthostatic Tachycardia Syndrome (POTS)
Alfredo Gamboa
NCT00962728
Transdermal Vagal Stimulation for POTS
Vanderbilt University
NCT02281097
The Exercise Response to Pharmacologic Cholinergic Stimulation in Myalgic Encephalomyelitis / Chronic Fatigue Syndrome
Brigham and Women's Hospital
NCT03674541
Non-invasive Vagal Neurostimulation (nVNS) in Adolescents With Postural Orthostatic Tachycardia Syndrome (POTS)
Mayo Clinic
NCT06268288
Dietary Sodium's Effect on Urinary Sodium and Dopamine Excretion in Patients With Postural Tachycardia Syndrome
Vanderbilt University Medical Center
NCT01563107
Effect of Ivabradine on Patients With Postural Orthostatic Tachycardia Syndrome
University of California, San Diego
NCT03182725
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Postural Orthostatic Tachycardia Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Postural Orthostatic Tachycardia Syndrome trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Postural Orthostatic Tachycardia Syndrome page
12 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Postural Orthostatic Tachycardia Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Vanderbilt University sponsors the most Postural Orthostatic Tachycardia Syndrome trials on record, review their full trial history before evaluating a specific study. See Vanderbilt University's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Postural Orthostatic Tachycardia Syndrome condition card totals 12 registered trials; most-linked intervention Placebo; top US site state Tennessee. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.