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NCT02196376 · ClinicalTrials.gov registry record

Assessment of Antibodies and Inflammatory Markers in Postural Tachycardia Syndrome

A clinical trial of Postural Orthostatic Tachycardia Syndrome, sponsored by Vanderbilt University.

Active
Registry status
212
Enrollment target
1
Study location

NCT02196376: Active study of Postural Orthostatic Tachycardia Syndrome, sponsored by Vanderbilt University.

NCT02196376 is a study of Postural Orthostatic Tachycardia Syndrome that is active but no longer recruiting, run by Vanderbilt University. The registered enrollment target is 212 participants, below the 9,225-participant average among 11 other Postural Orthostatic Tachycardia Syndrome trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02196376, a study of Postural Orthostatic Tachycardia Syndrome, is active but no longer recruiting, sponsored by Vanderbilt University.

ACTIVE NOT RECRUITING
Registry status
212 participants
Enrollment target
1
Study location

Study Summary

In this pilot study, the investigators will test the hypothesis that patients with postural tachycardia syndrome will have an elevated percentage of functional antibodies to adrenergic receptors compared with control subjects without POTS. The investigators further hypothesize that the percentage of POTS patients with antibodies will be higher in those patients with a viral infection at the onset of their illness than in those patients with other or undefined illness onsets.

Primary Outcome

The primary outcome measure will be the proportion of subjects with alpha-1 Ab titer. The primary comparison will be the proportion of Ab titers between POTS patients compared to control subjects.

Conditions Studied

Postural Orthostatic Tachycardia Syndrome

Interventions

  • BEHAVIORAL Questionnaires
  • OTHER blood draw
  • OTHER History
  • OTHER Physical

Study Locations (1)

Tennessee

  • Vanderbilt University Medical Center - Nashville

Trial Details

FieldValue
Enrollment Target 212 participants
Start Date 2014-07
Est. Completion 2029-07
Vanderbilt University

430 total trials

What the registry record for NCT02196376 still lists

NCT02196376 is an observational study that tracks outcomes without assigning an intervention. The registered 212 participants enrollment target is mid-sized for trials with a published cap, below the 9,225-participant average among 11 other Postural Orthostatic Tachycardia Syndrome trials with a reported enrollment target (98% lower).

The record links to 1 condition, with Postural Orthostatic Tachycardia Syndrome appearing as the primary indexed condition, and to 4 interventions - of which Questionnaires is the first listed.

NCT02196376 reports a single indexed study location in Tennessee.

Frequently Asked Questions

What is clinical trial NCT02196376 about?

NCT02196376 is a clinical study titled "Assessment of Antibodies and Inflammatory Markers in Postural Tachycardia Syndrome". In this pilot study, the investigators will test the hypothesis that patients with postural tachycardia syndrome will have an elevated percentage of functional antibodies to adrenergic receptors compared with control subjects without POTS. The investigators further hypothesize that the percentage of...

What is the current status of trial NCT02196376?

This trial is currently active not recruiting. The enrollment target is 212 participants. The study started on 2014-07. Estimated completion is 2029-07.

What conditions does trial NCT02196376 study?

This clinical trial studies the following conditions: Postural Orthostatic Tachycardia Syndrome.

What interventions are being tested in trial NCT02196376?

The interventions under investigation include: Questionnaires (BEHAVIORAL), blood draw (OTHER), History (OTHER), Physical (OTHER).

Who is sponsoring clinical trial NCT02196376?

This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02196376 being conducted?

This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Learn More About Clinical Trials

Similar trials for Postural Orthostatic Tachycardia Syndrome

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT02196376's enrollment target sits among peer trials

212 4th of 11 higher than 8 of 11 other Postural Orthostatic Tachycardia Syndrome trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Postural Orthostatic Tachycardia Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Related registry views

Source: ClinicalTrials.gov NCT02196376, the US trial registry maintained by the National Library of Medicine. NCT02196376 (mid enrollment · single site footprint · active not recruiting) retrieved and formatted by PlainTrial, see methodology.