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ClinicalTrials.gov 5 recruiting now official registry

Adenocarcinoma of the Rectum clinical trials

5 of 12 indexed Adenocarcinoma of the Rectum trials are currently recruiting.

12 US clinical trials · 5 currently recruiting

Adenocarcinoma of the Rectum is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 5 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 8 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 5 of these trials.

The research picture

Adenocarcinoma of the Rectum has 12 registered US clinical trials, 5 of them open to new participants right now, about 42% of the total.

5
recruiting participants now
42%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
5
top sponsor: National Cancer Institute (NCI)
Phase 15Phase 23

Active & Recent Trials

12 total, page 1 of 1

RECRUITING NA 9,500 participants

Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps

NRG Oncology

NCT05080673

RECRUITING 80 participants

Biopsy After Radioembolization to Identify Changes in Tumor Cells From the Radiation

Memorial Sloan Kettering Cancer Center

NCT04668872

RECRUITING 50 participants

The Utility and Feasibility of Mt-sDNA as a Surveillance Procedure in Colorectal Cancer Survivors

Case Comprehensive Cancer Center

NCT04624555

RECRUITING Phase 2 37 participants

A Study of Tucatinib and Trastuzumab in People With Rectal Cancer

Memorial Sloan Kettering Cancer Center

NCT05672524

RECRUITING NA 30 participants

A Study of Response to Standard Treatment Before Surgery in People With Rectal Cancer

Memorial Sloan Kettering Cancer Center

NCT06637462

COMPLETED Phase 2 159 participants

Phase 2 Study of ABT-869 in Combination With mFOLFOX6 Versus Bevacizumab in Combination With mFOLFOX6 to Treat Advanced Colorectal Cancer

AbbVie (prior sponsor, Abbott)

NCT00707889

COMPLETED Phase 1 48 participants

Vaccine Therapy With or Without Sargramostim in Treating Patients With Advanced or Metastatic Cancer

National Cancer Institute (NCI)

NCT00028496

COMPLETED Phase 1 43 participants

Erlotinib Hydrochloride and Cetuximab in Treating Patients With Advanced Gastrointestinal Cancer, Head and Neck Cancer, Non-Small Cell Lung Cancer, or Colorectal Cancer

National Cancer Institute (NCI)

NCT00397384

COMPLETED Phase 1 24 participants

Oxaliplatin, Fluorouracil, and External-Beam Radiation Therapy Followed by Surgery in Treating Patients With Locally Advanced Cancer of the Rectum

National Cancer Institute (NCI)

NCT00006094

COMPLETED Phase 2 20 participants

Non-Operative Radiation Management of Adenocarcinoma of the Lower Rectum

Washington University School of Medicine

NCT02641691

COMPLETED Phase 1 20 participants

Resveratrol in Treating Patients With Colorectal Cancer That Can Be Removed By Surgery

National Cancer Institute (NCI)

NCT00433576

COMPLETED Phase 1 15 participants

Radiolabeled Monoclonal Antibody Therapy in Treating Patients With Recurrent or Persistent Metastatic Colorectal Cancer

National Cancer Institute (NCI)

NCT00023933

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 3

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Adenocarcinoma of the Rectum Trial Landscape

12 indexed Adenocarcinoma of the Rectum studies · 5 recruiting (42%).

Phase mix: 0 late (III/IV) vs 8 early (I/II).

Top sponsor: National Cancer Institute (NCI) (5 trials), 5 others listed. 12 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Adenocarcinoma of the Rectum?

PlainTrial tracks 12 US clinical trials for Adenocarcinoma of the Rectum, of which 5 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Adenocarcinoma of the Rectum?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.