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NCT02281097 · ClinicalTrials.gov registry record · NA
Transdermal Vagal Stimulation for POTS
A NA study of Postural Orthostatic Tachycardia Syndrome, sponsored by Vanderbilt University.
- Active
- Registry status
- NA
- Development phase
- 18
- Enrollment target
- 1
- Study location
NCT02281097: Active NA study of Postural Orthostatic Tachycardia Syndrome, sponsored by Vanderbilt University.
NCT02281097 is a NA study of Postural Orthostatic Tachycardia Syndrome that is active but no longer recruiting, run by Vanderbilt University. The registered enrollment target is 18 participants, below the 9,243-participant average among 11 other Postural Orthostatic Tachycardia Syndrome trials with a reported enrollment target (100% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02281097, a NA study of Postural Orthostatic Tachycardia Syndrome, is active but no longer recruiting, sponsored by Vanderbilt University.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 18 participants
- Enrollment target
- 1
- Study location
Study Summary
Some patients experience high heart rates and symptoms of light-headedness, fatigue, headache during standing despite well maintained blood pressure. These patient are disabled and can't be in upright position for a longer time. The purpose of this study is to test whether electrical stimulation of a nerve through a skin of the ear may improve heart rate response and reduce disabling symptoms.
Primary Outcome
Upright heart rate and heart rate change from supine measured during graded tilt with 15 degrees increments each 5 minutes till 30 min of 75 degrees or abort.
Conditions Studied
Interventions
- OTHER Placebo
- OTHER Stimulation
Study Locations (1)
Tennessee
- Autonomic Dysfunction Center, Vanderbilt University Medical Center - Nashville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 18 participants |
| Start Date | 2013-06 |
| Est. Completion | 2025-12-31 |
| Phase | NA |
What the registry record for NCT02281097 still lists
NCT02281097 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 18 participants, a relatively small participant target, below the 9,243-participant average among 11 other Postural Orthostatic Tachycardia Syndrome trials with a reported enrollment target (100% lower).
The record links to 1 condition, with Postural Orthostatic Tachycardia Syndrome appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT02281097 reports a single indexed study location in Tennessee.
Frequently Asked Questions
What is clinical trial NCT02281097 about?
NCT02281097 is a clinical study titled "Transdermal Vagal Stimulation for POTS". Some patients experience high heart rates and symptoms of light-headedness, fatigue, headache during standing despite well maintained blood pressure. These patient are disabled and can't be in upright position for a longer time. The purpose of this study is to test whether electrical stimulation of...
What is the current status of trial NCT02281097?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 18 participants. The study started on 2013-06. Estimated completion is 2025-12-31.
What conditions does trial NCT02281097 study?
This clinical trial studies the following conditions: Postural Orthostatic Tachycardia Syndrome.
What interventions are being tested in trial NCT02281097?
The interventions under investigation include: Placebo (OTHER), Stimulation (OTHER).
Who is sponsoring clinical trial NCT02281097?
This trial is sponsored by Vanderbilt University, which has 430 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02281097 being conducted?
This trial has 1 study location across Tennessee. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02281097's enrollment target sits among peer trials
18 12th of 11 the lowest of 11 other Postural Orthostatic Tachycardia Syndrome trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Postural Orthostatic Tachycardia Syndrome trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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