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ClinicalTrials.gov 8 recruiting now early-phase tilt small index

Plasma Cell Leukemia: early-phase trial registry

8 of 13 indexed Plasma Cell Leukemia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,315 of 28,707 conditions by registered trial count.

13 US clinical trials · 8 currently recruiting · #1,315 of 28,707 conditions by registered trial count

Plasma Cell Leukemia: 13 US clinical trials tracked, 8 recruiting.

Plasma Cell Leukemia is the subject of 13 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is Masonic Cancer Center, University of Minnesota, running 3 of these trials.

Enrollment posture brief

Registry condition plasma-cell-leukemia

OPEN 8 | RECR 62% | LATE 0 | EARLY 9 | RANK #1315 | SPON 3

Nearest open-share peer: High Risk Myelodysplastic Syndrome (62% recruiting · 13 trials)

Plasma Cell Leukemia (this)62%ACL Injury61.5%Acute Biphenotypic Leukemia46.2%Accidental Falls30.8%Actinic Keratoses23.1%
Open-enrollment share among volume-matched conditions near Plasma Cell Leukemia

Plasma Cell Leukemia lists 8 open slots (62% of 13 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Plasma Cell Leukemia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Plasma Cell Leukemia is recruiting above its size-band peers.

    8 of 13 indexed trials (61.5%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Plasma Cell Leukemia research.

    Masonic Cancer Center, University of Minnesota accounts for 3 of 13 trials (23.1%). 10 distinct sponsors appear on at least one study for this condition label.

  3. Most Plasma Cell Leukemia trials plan to enrol fewer than 100 people.

    Median target enrolment is 56 among the 13 trials that report a genuine target (sentinel values excluded). 8 of those (61.5%) plan for fewer than 100 participants.

  4. Plasma Cell Leukemia research is mostly interventional.

    11 interventional and 2 observational studies make up this index (84.6% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 25

Open and recent trials

13 total, page 1 of 1

RECRUITING 5,000 participants

Cancer and Aging Resilience Evaluation in Older Adults With Hematologic Malignancies: The CARE-Heme Registry

University of Alabama at Birmingham

NCT05556928

RECRUITING 2,000 participants

Registry for Adults With Plasma Cell Disorders (PCD's)

UNC Lineberger Comprehensive Cancer Center

NCT03717844

RECRUITING Phase 2 300 participants

Myeloablative Allo HSCT With Related or Unrelated Donor for Heme Disorders

Masonic Cancer Center, University of Minnesota

NCT03314974

RECRUITING NA 200 participants

Umbilical Cord Blood Transplantation Using a Myeloablative Preparative Regimen for Hematological Diseases

Masonic Cancer Center, University of Minnesota

NCT01962636

RECRUITING Phase 2 120 participants

Impact of Budesonide on Incidence of ≥ Gr2 Diarrhea in Multiple Myeloma (MM) Patients Undergoing Autologous Stem Cell Transplant

University of Utah

NCT05405387

RECRUITING Phase 1 80 participants

Phase I/II Study of CAR.70- Engineered IL15-transduced Cord Blood-derived NK Cells in Conjunction With Lymphodepleting Chemotherapy for the Management of Relapse/Refractory Hematological Malignances

M.D. Anderson Cancer Center

NCT05092451

RECRUITING Phase 2 56 participants

Allo HSCT Using RIC and PTCy for Hematological Diseases

Masonic Cancer Center, University of Minnesota

NCT05805605

RECRUITING Phase 2 40 participants

Use of Isatuximab, Dexamethasone and Lenalidomide in a Go-Slow Fashion for Ultra-Frail Patients With Multiple Myeloma

University of Utah

NCT06517017

ACTIVE NOT RECRUITING NA 40 participants

High Throughput Drug Sensitivity and Genomics Data in Developing Individualized Treatment in Patients With Relapsed or Refractory Multiple Myeloma or Plasma Cell Leukemia

University of Washington

NCT03389347

ACTIVE NOT RECRUITING Phase 1 32 participants

Itacitinib With High-dose Posttransplantation Cyclophosphamide in Older Patients

Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins

NCT05823571

COMPLETED Phase 2 30 participants

Bortezomib Followed by High-Dose Melphalan and Bortezomib as Conditioning Regimen for Tandem Stem Cell Transplants

H. Lee Moffitt Cancer Center and Research Institute

NCT00307086

COMPLETED Phase 1 18 participants

Bortezomib, Total Marrow Irradiation, Fludarabine Phosphate, and Melphalan in Treating Patients Undergoing Donor Peripheral Blood Stem Cell Transplant For High-Risk Stage I or II Multiple Myeloma

City of Hope Medical Center

NCT01163357

COMPLETED Phase 1 11 participants

Combination Chemotherapy and Donor Stem Cell Transplant Followed by Ixazomib Citrate Maintenance Therapy in Treating Patients With Relapsed High-Risk Multiple Myeloma

OHSU Knight Cancer Institute

NCT02504359

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 5

Named interventions

Most-linked intervention names on Plasma Cell Leukemia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cyclophosphamide Drug
3 trials
Fludarabine Drug
2 trials
melphalan Other
1 trials
PBSCT Procedure
1 trials
total marrow irradiation Radiation
1 trials
bortezomib Drug
1 trials
High Throughput Screening Device
1 trials
Mycophenylate mofetil Drug
1 trials

US sites by state

Facility locations filed on Plasma Cell Leukemia trials. A trial with sites in several states counts in each.

Minnesota 3 trials
Utah 2 trials
North Carolina 2 trials
Washington 1 trials
Texas 1 trials
Oregon 1 trials
Maryland 1 trials
Florida 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Plasma Cell Leukemia page

13 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Plasma Cell Leukemia condition card totals 13 registered trials; most-linked intervention Cyclophosphamide; top US site state Minnesota. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.