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ClinicalTrials.gov 14 recruiting now early-phase tilt

Peripheral T-Cell Lymphoma: early-phase trial registry

14 of 35 indexed Peripheral T-Cell Lymphoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #435 of 28,707 conditions by registered trial count.

35 US clinical trials · 14 currently recruiting · #435 of 28,707 conditions by registered trial count

Peripheral T-Cell Lymphoma: 35 US clinical trials tracked, 14 recruiting.

Peripheral T-Cell Lymphoma is the subject of 35 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 32 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 3 of these trials.

Enrollment posture brief

Registry condition peripheral-t-cell-lymphoma

OPEN 14 | RECR 40% | LATE 1 | EARLY 32 | RANK #435 | SPON 3

Nearest open-share peer: Achondroplasia (40% recruiting · 10 trials)

Cannabis Use Disorder71.4%Cirrhosis, Liver60%Peripheral T-Cell Lympho (th…40%Carcinoma, Renal Cell17.1%Advanced Lymphoma8.6%
Open-enrollment share among volume-matched conditions near Peripheral T-Cell Lymphoma

Peripheral T-Cell Lymphoma lists 14 open slots (40% of 35 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Peripheral T-Cell Lymphoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Peripheral T-Cell Lymphoma recruits in line with its size-band peers.

    14 of 35 indexed trials (40%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Peripheral T-Cell Lymphoma trials is spread across many organizations.

    National Cancer Institute (NCI) accounts for 3 of 35 trials (8.6%). 30 distinct sponsors appear on at least one study for this condition label.

  3. Most Peripheral T-Cell Lymphoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 44 among the 35 trials that report a genuine target (sentinel values excluded). 25 of those (71.4%) plan for fewer than 100 participants.

  4. Peripheral T-Cell Lymphoma research is mostly interventional.

    34 interventional and 1 observational studies make up this index (97.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 115Phase 217Phase 31

Open and recent trials

35 total, page 1 of 1

RECRUITING 1,000 participants

Prospective Observational International Registry of Patients With Newly Diagnosed Peripheral T Cell Lymphoma.

Associazione Angela Serra per la ricerca sul cancro

NCT03964480

RECRUITING Phase 3 504 participants

To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL

Acrotech Biopharma

NCT06072131

RECRUITING Phase 1 254 participants

Evaluate the Safety and Clinical Activity of HH2853

Haihe Biopharma Co.

NCT04390737

RECRUITING Phase 1 250 participants

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

CellCentric

NCT04068597

RECRUITING Phase 1 90 participants

Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas

Baylor College of Medicine

NCT06176690

RECRUITING Phase 1 60 participants

A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)

National Cancer Institute (NCI)

NCT07055477

RECRUITING Phase 2 53 participants

Amping up With PemJAK

Seda S. Tolu

NCT07283822

RECRUITING Phase 1 46 participants

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

SciTech Development

NCT04234048

RECRUITING Phase 2 44 participants

Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell Lymphoma

Jonathan Brammer

NCT07356245

RECRUITING Early Phase 1 40 participants

Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma

New York Medical College

NCT03719105

RECRUITING Phase 2 30 participants

A Phase II, Single-center, Single-arm Study Evaluating the Safety and Efficacy of Golidocitinib in the Management of Newly Diagnosed Peripheral T Cell Lymphoma Patients (GOLDEN Study) and Correlative Study

M.D. Anderson Cancer Center

NCT06630091

RECRUITING Phase 1 21 participants

Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma

Mayo Clinic

NCT06508463

RECRUITING Phase 2 20 participants

CD30 CAR for Relapsed/Refractory CD30+ T Cell Lymphoma

UNC Lineberger Comprehensive Cancer Center

NCT04083495

RECRUITING NA 20 participants

A Pilot of a Microdevice For In Situ Candidate Drug Screening in Cutaneous Lesions of T-Cell Lymphoma

Dana-Farber Cancer Institute

NCT04045470

ACTIVE NOT RECRUITING Phase 2 30 participants

Romidepsin and Lenalidomide in Treating Patients With Previously Untreated Peripheral T-Cell Lymphoma

Northwestern University

NCT02232516

ACTIVE NOT RECRUITING Phase 1 21 participants

Phase 1 Study of Autologous CD30.CAR-T in Relapsed or Refractory CD30 Positive Non-Hodgkin Lymphoma

Tessa Therapeutics

NCT04526834

ACTIVE NOT RECRUITING Phase 1 6 participants

A Study to Learn About the Study Medicine Called PF-08046032 in People With Advanced Cancers

Pfizer

NCT06870487

ACTIVE NOT RECRUITING Phase 1 6 participants

Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies

Washington University School of Medicine

NCT05377827

COMPLETED Phase 2 156 participants

A Study of Duvelisib in Participants With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

SecuraBio

NCT03372057

COMPLETED Phase 2 131 participants

Depsipeptide to Treat Patients With Cutaneous T-Cell Lymphoma and Peripheral T-Cell Lymphoma

National Cancer Institute (NCI)

NCT00007345

COMPLETED Phase 2 131 participants

A Study of Brentuximab Vedotin With Hodgkin Lymphoma (HL) and CD30-expressing Peripheral T-cell Lymphoma (PTCL)

Seagen

NCT01716806

COMPLETED Phase 2 129 participants

Belinostat in Relapsed or Refractory Peripheral T-Cell Lymphoma

Spectrum Pharmaceuticals

NCT00865969

COMPLETED Phase 2 115 participants

Study of Pralatrexate With Vitamin B12 and Folic Acid in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma

Acrotech Biopharma

NCT00364923

COMPLETED Phase 2 108 participants

Phase II Study to Assess AFM13 in Patients With R/R CD30-positive T-cell Lymphoma or Transformed Mycosis Fungoides

Affimed

NCT04101331

COMPLETED Phase 2 82 participants

Pembrolizumab After ASCT for Hodgkin Lymphoma, DLBCL and T-NHL

Dana-Farber Cancer Institute

NCT02362997

COMPLETED Phase 2 82 participants

A Study of Brentuximab Vedotin and CHP in Frontline Treatment of PTCL With Less Than 10% CD30 Expression

Seagen, a wholly owned subsidiary of Pfizer

NCT04569032

COMPLETED Phase 1 50 participants

Oral Clofarabine for Relapsed/Refractory Non-Hodgkin Lymphoma

Massachusetts General Hospital

NCT00644189

COMPLETED Phase 2 41 participants

Panobinostat in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

Mayo Clinic

NCT01261247

COMPLETED Phase 1 26 participants

BR101801 in Adult Patients With Advanced Hematologic Malignancies(Phase I)

Boryung Pharmaceutical Co.

NCT04018248

COMPLETED Phase 1 20 participants

Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies

Case Comprehensive Cancer Center

NCT01658319

COMPLETED Phase 1 15 participants

Carfilzomib in Treating Patients With Relapsed or Refractory T-Cell Lymphoma

University of Nebraska

NCT01336920

COMPLETED Phase 2 14 participants

Sorafenib Tosylate in Treating Patients With Recurrent Aggressive Non-Hodgkin's Lymphoma

National Cancer Institute (NCI)

NCT00131937

COMPLETED Phase 1 8 participants

Bortezomib and Azacitidine in Treating Patients With Relapsed or Refractory T-Cell Lymphoma

Pierluigi Porcu

NCT01129180

COMPLETED Phase 2 6 participants

Letermovir for the Prevention of Cytomegalovirus Reactivation in Patients With Hematological Malignancies Treated With Alemtuzumab

Ohio State University Comprehensive Cancer Center

NCT04312841

COMPLETED Phase 2 4 participants

Nivolumab and the Antagonistic CSF-1R Monoclonal Antibody Cabiralizumab (BMS-986227) in Patients With Relapsed/Refractory Peripheral T Cell Lymphoma

University of Michigan Rogel Cancer Center

NCT03927105

Phase Distribution

PhaseTrial count
Phase 1 15
Phase 2 17
Phase 3 1

Top Sponsors

Named interventions

Most-linked intervention names on Peripheral T-Cell Lymphoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

laboratory biomarker analysis Other
3 trials
Cyclophosphamide Drug
3 trials
western blotting Genetic
2 trials
brentuximab vedotin Drug
2 trials
Pralatrexate Injection Drug
2 trials
Ruxolitinib Drug
2 trials
Dexamethasone Drug
2 trials
Bone Marrow Biopsy Procedure
2 trials

US sites by state

Facility locations filed on Peripheral T-Cell Lymphoma trials. A trial with sites in several states counts in each.

California 14 trials
Texas 12 trials
New York 10 trials
Ohio 8 trials
Michigan 8 trials
Massachusetts 7 trials
Illinois 7 trials
Georgia 7 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Peripheral T-Cell Lymphoma page

35 registered trials, 14 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Peripheral T-Cell Lymphoma condition card totals 35 registered trials; most-linked intervention laboratory biomarker analysis; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.