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ClinicalTrials.gov 14 recruiting now official registry

Peripheral T-Cell Lymphoma clinical trials

14 of 35 indexed Peripheral T-Cell Lymphoma trials are currently recruiting.

35 US clinical trials · 14 currently recruiting

Peripheral T-Cell Lymphoma is the subject of 35 registered US clinical trials on ClinicalTrials.gov, 14 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 32 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 3 of these trials.

The research picture

Peripheral T-Cell Lymphoma has 35 registered US clinical trials, 14 of them open to new participants right now, about 40% of the total.

14
recruiting participants now
40%
of trials open to enrollment
1
in Phase 3–4 (later-stage)
3
top sponsor: National Cancer Institute (NCI)
Phase 115Phase 217Phase 31

Active & Recent Trials

35 total, page 1 of 1

RECRUITING 1,000 participants

Prospective Observational International Registry of Patients With Newly Diagnosed Peripheral T Cell Lymphoma.

Associazione Angela Serra per la ricerca sul cancro

NCT03964480

RECRUITING Phase 3 504 participants

To Evaluate Efficacy of Belinostat or Pralatrexate in Combination Against CHOP Alone in PTCL

Acrotech Biopharma

NCT06072131

RECRUITING Phase 1 254 participants

Evaluate the Safety and Clinical Activity of HH2853

Haihe Biopharma Co.

NCT04390737

RECRUITING Phase 1 250 participants

Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies

CellCentric

NCT04068597

RECRUITING Phase 1 90 participants

Constitutive IL7R (C7R) Modified Banked Allogeneic CD30.CAR EBVSTS for CD30-Positive Lymphomas

Baylor College of Medicine

NCT06176690

RECRUITING Phase 1 60 participants

A Phase I Trial Anti-CC Chemokine Receptor 4 Chimeric Antigen Receptor T Cells (CCR4 CAR T Cells) for CCR4 Expressing T-cell Malignancies Including Peripheral T-cell Non-Hodgkin Lymphoma (PTCL) and Cutaneous T-cell Non-Hodgkin Lymphoma (CTCL)

National Cancer Institute (NCI)

NCT07055477

RECRUITING Phase 2 53 participants

Amping up With PemJAK

Seda S. Tolu

NCT07283822

RECRUITING Phase 1 46 participants

Phase 1 Trial of ST-001 nanoFenretinide in Relapsed/Refractory T-cell Non-Hodgkin Lymphoma

SciTech Development

NCT04234048

RECRUITING Phase 2 44 participants

Ruxolitinib Maintenance Post-Hematopoietic Stem Cell Transplant T-Cell Lymphoma

Jonathan Brammer

NCT07356245

RECRUITING Early Phase 1 40 participants

Chemoimmunotherapy and Allogeneic Stem Cell Transplant for NK T-cell Leukemia/Lymphoma

New York Medical College

NCT03719105

RECRUITING Phase 2 30 participants

A Phase II, Single-center, Single-arm Study Evaluating the Safety and Efficacy of Golidocitinib in the Management of Newly Diagnosed Peripheral T Cell Lymphoma Patients (GOLDEN Study) and Correlative Study

M.D. Anderson Cancer Center

NCT06630091

RECRUITING Phase 1 21 participants

Intravenous Vesicular Stomatitis Virus in Patients With Peripheral T-cell Lymphoma

Mayo Clinic

NCT06508463

RECRUITING Phase 2 20 participants

CD30 CAR for Relapsed/Refractory CD30+ T Cell Lymphoma

UNC Lineberger Comprehensive Cancer Center

NCT04083495

RECRUITING NA 20 participants

A Pilot of a Microdevice For In Situ Candidate Drug Screening in Cutaneous Lesions of T-Cell Lymphoma

Dana-Farber Cancer Institute

NCT04045470

ACTIVE NOT RECRUITING Phase 2 30 participants

Romidepsin and Lenalidomide in Treating Patients With Previously Untreated Peripheral T-Cell Lymphoma

Northwestern University

NCT02232516

ACTIVE NOT RECRUITING Phase 1 21 participants

Phase 1 Study of Autologous CD30.CAR-T in Relapsed or Refractory CD30 Positive Non-Hodgkin Lymphoma

Tessa Therapeutics

NCT04526834

ACTIVE NOT RECRUITING Phase 1 6 participants

A Study to Learn About the Study Medicine Called PF-08046032 in People With Advanced Cancers

Pfizer

NCT06870487

ACTIVE NOT RECRUITING Phase 1 6 participants

Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies

Washington University School of Medicine

NCT05377827

COMPLETED Phase 2 156 participants

A Study of Duvelisib in Participants With Relapsed or Refractory Peripheral T-cell Lymphoma (PTCL)

SecuraBio

NCT03372057

COMPLETED Phase 2 131 participants

Depsipeptide to Treat Patients With Cutaneous T-Cell Lymphoma and Peripheral T-Cell Lymphoma

National Cancer Institute (NCI)

NCT00007345

COMPLETED Phase 2 131 participants

A Study of Brentuximab Vedotin With Hodgkin Lymphoma (HL) and CD30-expressing Peripheral T-cell Lymphoma (PTCL)

Seagen

NCT01716806

COMPLETED Phase 2 129 participants

Belinostat in Relapsed or Refractory Peripheral T-Cell Lymphoma

Spectrum Pharmaceuticals

NCT00865969

COMPLETED Phase 2 115 participants

Study of Pralatrexate With Vitamin B12 and Folic Acid in Patients With Relapsed or Refractory Peripheral T-cell Lymphoma

Acrotech Biopharma

NCT00364923

COMPLETED Phase 2 108 participants

Phase II Study to Assess AFM13 in Patients With R/R CD30-positive T-cell Lymphoma or Transformed Mycosis Fungoides

Affimed

NCT04101331

COMPLETED Phase 2 82 participants

Pembrolizumab After ASCT for Hodgkin Lymphoma, DLBCL and T-NHL

Dana-Farber Cancer Institute

NCT02362997

COMPLETED Phase 2 82 participants

A Study of Brentuximab Vedotin and CHP in Frontline Treatment of PTCL With Less Than 10% CD30 Expression

Seagen, a wholly owned subsidiary of Pfizer

NCT04569032

COMPLETED Phase 1 50 participants

Oral Clofarabine for Relapsed/Refractory Non-Hodgkin Lymphoma

Massachusetts General Hospital

NCT00644189

COMPLETED Phase 2 41 participants

Panobinostat in Treating Patients With Relapsed or Refractory Non-Hodgkin Lymphoma

Mayo Clinic

NCT01261247

COMPLETED Phase 1 26 participants

BR101801 in Adult Patients With Advanced Hematologic Malignancies(Phase I)

Boryung Pharmaceutical Co.

NCT04018248

COMPLETED Phase 1 20 participants

Methoxyamine and Fludarabine Phosphate in Treating Patients With Relapsed or Refractory Hematologic Malignancies

Case Comprehensive Cancer Center

NCT01658319

COMPLETED Phase 1 15 participants

Carfilzomib in Treating Patients With Relapsed or Refractory T-Cell Lymphoma

University of Nebraska

NCT01336920

COMPLETED Phase 2 14 participants

Sorafenib Tosylate in Treating Patients With Recurrent Aggressive Non-Hodgkin's Lymphoma

National Cancer Institute (NCI)

NCT00131937

COMPLETED Phase 1 8 participants

Bortezomib and Azacitidine in Treating Patients With Relapsed or Refractory T-Cell Lymphoma

Pierluigi Porcu

NCT01129180

COMPLETED Phase 2 6 participants

Letermovir for the Prevention of Cytomegalovirus Reactivation in Patients With Hematological Malignancies Treated With Alemtuzumab

Ohio State University Comprehensive Cancer Center

NCT04312841

COMPLETED Phase 2 4 participants

Nivolumab and the Antagonistic CSF-1R Monoclonal Antibody Cabiralizumab (BMS-986227) in Patients With Relapsed/Refractory Peripheral T Cell Lymphoma

University of Michigan Rogel Cancer Center

NCT03927105

Phase Distribution

PhaseTrial count
Phase 1 15
Phase 2 17
Phase 3 1

Top Sponsors

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Peripheral T-Cell Lymphoma Trial Landscape

35 indexed Peripheral T-Cell Lymphoma studies · 14 recruiting (40%).

Phase mix: 1 late (III/IV) vs 32 early (I/II).

Top sponsor: National Cancer Institute (NCI) (3 trials), 9 others listed. 35 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Peripheral T-Cell Lymphoma?

PlainTrial tracks 35 US clinical trials for Peripheral T-Cell Lymphoma, of which 14 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Peripheral T-Cell Lymphoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.