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A Study of Brentuximab Vedotin With Hodgkin Lymphoma (HL) and CD30-expressing Peripheral T-cell Lymphoma (PTCL)
NCT01716806 · View on ClinicalTrials.gov ↗
Study Summary
This trial will study brentuximab vedotin to find out whether it is an effective treatment for Hodgkin lymphoma (HL) and peripheral T-cell lymphoma (PTCL). Participants in this study will be older or will have other conditions that make them unable to have standard chemotherapy treatment. The study will look at brentuximab vedotin alone and combined with other drugs.
Conditions Studied
Interventions
- DRUG nivolumab
- DRUG brentuximab vedotin
- DRUG bendamustine
- DRUG dacarbazine
Study Locations (20)
Arizona
- Banner MD Anderson Cancer Center — Gilbert
- Arizona Oncology Associates, PC - HOPE — Tucson
- Arizona Cancer Center / University of Arizona — Tucson
California
- Providence St Joseph Medical Center — Burbank
- City of Hope National Medical Center — Duarte
- Wilshire Oncology Medical Group Inc. — Pomona
Alabama
- University of Alabama at Birmingham — Birmingham
- University of South Alabama - Mitchell Cancer Institute — Mobile
Georgia
- IACT Health — Columbus
- Georgia Cancer Specialists / Northside Hospital Cancer Institute — Sandy Springs
Illinois
- Rush University Medical Center — Chicago
- Illinois Cancer Specialists / Advocate Lutheran General Hospital — Niles
Alaska
- Alaska Urological Institute — Anchorage
Arkansas
- Highlands Oncology Group — Springdale
Colorado
- Rocky Mountain Cancer Centers - Aurora — Aurora
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 131 participants |
| Start Date | 2012-10-31 |
| Est. Completion | 2023-09-12 |
| Phase | Phase 2 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT01716806
The ClinicalTrials.gov registry entry for NCT01716806 describes a study currently listed as completed. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 131 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Seagen, which has 12 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Hodgkin Disease appearing as the primary indexed condition, and to 4 interventions — of which nivolumab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT01716806 reports 20 study locations spanning 13 distinct geographic areas — top geographies include Arizona, California, Alabama. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT01716806 about?
NCT01716806 is a clinical study titled "A Study of Brentuximab Vedotin With Hodgkin Lymphoma (HL) and CD30-expressing Peripheral T-cell Lymphoma (PTCL)". This trial will study brentuximab vedotin to find out whether it is an effective treatment for Hodgkin lymphoma (HL) and peripheral T-cell lymphoma (PTCL). Participants in this study will be older or will have other conditions that make them unable to have standard chemotherapy treatment. The study ...
What is the current status of trial NCT01716806?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 131 participants. The study started on 2012-10-31. Estimated completion is 2023-09-12.
What conditions does trial NCT01716806 study?
This clinical trial studies the following conditions: Hodgkin Disease, Peripheral T Cell Lymphoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT01716806?
The interventions under investigation include: nivolumab (DRUG), brentuximab vedotin (DRUG), bendamustine (DRUG), dacarbazine (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT01716806?
This trial is sponsored by Seagen, which has 12 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT01716806 being conducted?
This trial has 20 study locations across Alabama, Alaska, Arizona, Arkansas, California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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