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NCT01336920 · ClinicalTrials.gov registry record · Phase 1
Carfilzomib in Treating Patients With Relapsed or Refractory T-Cell Lymphoma
A Phase 1 study of Peripheral T-Cell Lymphoma and Anaplastic Large Cell Lymphoma, sponsored by University of Nebraska.
- Completed
- Registry status
- Phase 1
- Development phase
- 15
- Enrollment target
- 3
- Study locations
NCT01336920: Completed Phase 1 study of Peripheral T-Cell Lymphoma and Anaplastic Large Cell Lymphoma, sponsored by University of Nebraska.
NCT01336920 is a Phase 1 study of Peripheral T-Cell Lymphoma and Anaplastic Large Cell Lymphoma that has completed, run by University of Nebraska. The registered enrollment target is 15 participants, below the 106-participant average among 34 other Peripheral T-Cell Lymphoma trials with a reported enrollment target (86% lower). The trial reports 3 study locations across 3 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT01336920, a Phase 1 study of Peripheral T-Cell Lymphoma and Anaplastic Large Cell Lymphoma, has completed, sponsored by University of Nebraska.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 15 participants
- Enrollment target
- 3
- Study locations
Study Summary
This phase I trial studies the side effects and best dose of carfilzomib in treating patients with relapsed or refractory T-cell lymphoma. Carfilzomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
Primary Outcome
MTD of carfilzomib, determined by incidence of dose-limiting toxicity (DLT) as assessed by the National Cancer Institute (NCI) Common Terminology Criteria for Adverse Events (CTCAE) version 4.0.
Conditions Studied
Interventions
- DRUG carfilzomib
Study Locations (3)
Georgia
- Emory University, Winship Cancer Institute - Atlanta
Nebraska
- University of Nebraska Medical Center - Omaha
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 15 participants |
| Start Date | 2011-06-21 |
| Est. Completion | 2018-03-01 |
| Phase | Phase 1 |
What the finished NCT01336920 record still lists
NCT01336920 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 106-participant average among 34 other Peripheral T-Cell Lymphoma trials with a reported enrollment target (86% lower).
The record links to 5 conditions, with Peripheral T-Cell Lymphoma appearing as the primary indexed condition, and to 1 intervention - of which carfilzomib is the first listed.
NCT01336920 reports a single indexed study location in Georgia, Nebraska, Texas.
Frequently Asked Questions
What is clinical trial NCT01336920 about?
NCT01336920 is a clinical study titled "Carfilzomib in Treating Patients With Relapsed or Refractory T-Cell Lymphoma". This phase I trial studies the side effects and best dose of carfilzomib in treating patients with relapsed or refractory T-cell lymphoma. Carfilzomib may stop the growth of cancer cells by blocking some of the enzymes needed for cell growth.
What is the current status of trial NCT01336920?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 15 participants. The study started on 2011-06-21. Estimated completion is 2018-03-01.
What conditions does trial NCT01336920 study?
This clinical trial studies the following conditions: Peripheral T-Cell Lymphoma, Anaplastic Large Cell Lymphoma, Angioimmunoblastic T-cell Lymphoma, Adult Nasal Type Extranodal NK/T-cell Lymphoma, Recurrent Adult T-Cell Leukemia/Lymphoma.
What interventions are being tested in trial NCT01336920?
The interventions under investigation include: carfilzomib (DRUG).
Who is sponsoring clinical trial NCT01336920?
This trial is sponsored by University of Nebraska, which has 407 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT01336920 being conducted?
This trial has 3 study locations across Georgia, Nebraska, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT01336920's enrollment target sits among peer trials
15 29th of 34 higher than 6 of 34 other Peripheral T-Cell Lymphoma trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Peripheral T-Cell Lymphoma trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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