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Pelvic Organ Prolapse: later-stage trial registry
8 of 41 indexed Pelvic Organ Prolapse trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #357 of 28,707 conditions by registered trial count.
41 US clinical trials · 8 currently recruiting · #357 of 28,707 conditions by registered trial count
Pelvic Organ Prolapse: 41 US clinical trials tracked, 8 recruiting.
Pelvic Organ Prolapse is the subject of 41 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 4 are in Phase 3-4 (later-stage) and 0 in Phase 1-2 (earlier-stage). The most active sponsor is Mayo Clinic, running 3 of these trials.
Enrollment posture brief
Registry condition pelvic-organ-prolapse
OPEN 8 | RECR 20% | LATE 4 | EARLY 0 | RANK #357 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Anaplastic Large Cell Lymphoma (19% recruiting · 26 trials)
Pelvic Organ Prolapse lists 8 open slots (20% of 41 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Pelvic Organ Prolapse on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Pelvic Organ Prolapse is recruiting below its size-band peers.
8 of 41 indexed trials (19.5%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Pelvic Organ Prolapse trials is spread across many organizations.
Mayo Clinic accounts for 3 of 41 trials (7.3%). 33 distinct sponsors appear on at least one study for this condition label.
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Typical Pelvic Organ Prolapse enrolment sits around 103 participants.
Median target enrolment is 103 among the 41 trials that report a genuine target (sentinel values excluded). 18 of those (43.9%) plan for fewer than 100 participants.
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Pelvic Organ Prolapse splits between interventional and observational designs.
26 interventional and 15 observational studies make up this index (63.4% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
41 total, page 1 of 1
Ethicon Pelvic Mesh Post Market Clinical Follow-up Registry
Ethicon
NCT04829175
The AccelERate Trial
NICHD Pelvic Floor Disorders Network
NCT07218016
POMEGRANATE Trial: Comparing Reia Pessary Versus Standard of Care Pessary for Pelvic Organ Prolapse Treatment
Medstar Health Research Institute
NCT06634459
SORE Study: Sitz Baths After Urogynecologic Reconstruction
Yale University
NCT07215780
Sequence of Midurethral Sling Placement During Robotic Sacrocolpopexy
University of Alabama at Birmingham
NCT07008898
Centered Surgery - Preoperative Counseling and Patient Satisfaction
The Cleveland Clinic
NCT07471464
GYNEMESH PS Mesh Post Marketing Clinical Follow-Up Study
Ethicon
NCT04829058
Pessary Experience Study
University of Virginia
NCT06021769
EASE: The Materna Prep Pivotal Study
Materna Medical
NCT03973281
Cranberry Tablets Versus Nitrofurantoin Prophylaxis for Urinary Tract Infection Prevention After Urogynecologic Surgery
Brigham and Women's Hospital
NCT03522961
SCP vs HUSLS for Pelvic Organ Prolapse Repair
Loma Linda University
NCT02800512
Intraoperative Costs and Patient Perceptions in Sacrocolpopexy for Prolapse
Mayo Clinic
NCT04179955
Platelet Rich Plasma as an Adjunct Therapy at the Time of Transvaginal Native Tissue Prolapse Surgery
University of Alabama at Birmingham
NCT05731284
Clinical Investigation of the da Vinci Surgical System
Intuitive Surgical
NCT05682742
Vaginal Orthosis Use After Vaginal Reconstructive Surgery
University of Alabama at Birmingham
NCT05812859
Comparison of 2 Lightweight Y-meshes After Laparoscopic Sacrocolpopexy
Atlantic Health System
NCT02248935
The Extended Operations And Pelvic Muscle Training In The Management Of Apical Support Loss Study
NICHD Pelvic Floor Disorders Network
NCT01166373
Race, Ethnicity, Socioeconomic Status and Prolapse-rElated Decisional ConflicT
Women and Infants Hospital of Rhode Island
NCT04977141
Predictors of Recovery Expectancy
Indiana University
NCT04274491
Validation of Transvaginal Tactile Imaging
Artann Laboratories
NCT01491334
Nitrofurantoin Prophylaxis During Catheter-managed Acute Urinary Retention After Pelvic Reconstructive Surgery
Halina M Zyczynski, MD
NCT02727322
Colpocleisis for Advanced Pelvic Organ Prolapse
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00271037
Predictors of Post Operative Morbidity in Older Women With Pelvic Organ Prolapse
University of Pennsylvania
NCT01967446
Pelvic Floor Disorder Assessment of Knowledge and Symptoms: an Educational Model in Spanish-Speaking Women
Johns Hopkins University
NCT04829721
Voiding Assessment Based on Minimum Spontaneous Void of 150 mL Compared to Retrograde Fill Method After Female Pelvic Floor Reconstructive Surgery
Yale University
NCT03539107
Preoperative Gabapentin vs Placebo for Vaginal Prolapse Surgery
Joseph Kowalski
NCT05658887
Caregiver Support and Post-operative Convalescence
Icahn School of Medicine at Mount Sinai
NCT04897061
The Purpose of This Study is to Look at Pelvic Support Problems, Also Commonly Known as Pelvic Organ Prolapse
University of Oklahoma
NCT00964197
Impact of Level III Support Procedure on Enlarged Genital Hiatus After Minimally Invasive Sacrocolpopexy
University of Pittsburgh
NCT04480671
Abdominal Colpopexy: Comparison of Endoscopic Surgical Strategies
Loyola University
NCT01124916
Feasibility Study of the Reia Vaginal Pessary
Reia
NCT04508335
Axis™ Allograft Dermis for Female Pelvic Floor Repair: a Prospective Post Market Study
Coloplast A/S
NCT01541748
Pudendal Nerve Block in Vaginal Surgery
MetroHealth Medical Center
NCT04198714
Lidocaine for Pessary Check Pain Reduction
University of South Florida
NCT05493735
Timing of Repeat Voiding Trials After Outpatient Pelvic Floor Surgery
The Cleveland Clinic
NCT03048682
Effects of Preoperative Dexamethasone Study on QOL After Vaginal Reconstructive Surgery for POP
TriHealth
NCT02073734
EVeRLAST 2-Year Follow-Up
Duke University
NCT05542836
Prediction of Postsurgical Symptomatic Outcomes With Preoperative Pessary Use
Mayo Clinic
NCT02680145
Analysis of Procedural Times Using Colpassist for Robotic-Assisted Sacrocolpopexy; a Randomized Controlled Trial
University of North Carolina, Chapel Hill
NCT02367235
Perineorrhaphy Outcomes Related to Body Imagery
University of New Mexi
NCT02548858
Advanced Biomarker Assessment in Pelvic Organ Prolapse
Mayo Clinic
NCT03642054
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 3 | 2 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Pelvic Organ Prolapse records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Pelvic Organ Prolapse trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Pelvic Organ Prolapse page
41 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 8 Pelvic Organ Prolapse trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Mayo Clinic sponsors the most Pelvic Organ Prolapse trials on record, review their full trial history before evaluating a specific study. See Mayo Clinic's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pelvic Organ Prolapse condition card totals 41 registered trials; most-linked intervention Intervention; top US site state Pennsylvania. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.