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Osteoporosis: full-pipeline trial registry
11 of 87 indexed Osteoporosis trials are currently recruiting.
Corpus placement: #158 of 28,707 conditions by registered trial count.
87 US clinical trials · 11 currently recruiting · #158 of 28,707 conditions by registered trial count
Osteoporosis: 87 US clinical trials tracked, 11 recruiting.
Osteoporosis is the subject of 87 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 28 are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most active sponsor is University of Colorado, Denver, running 4 of these trials.
Enrollment posture brief
Registry condition osteoporosis
OPEN 11 | RECR 13% | LATE 28 | EARLY 21 | RANK #158 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Acute Respiratory Infection (13% recruiting · 8 trials)
Osteoporosis lists 11 open slots (13% of 87 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Osteoporosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Osteoporosis is recruiting below its size-band peers.
11 of 87 indexed trials (12.6%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Osteoporosis trials is spread across many organizations.
University of Colorado, Denver accounts for 4 of 87 trials (4.6%). 65 distinct sponsors appear on at least one study for this condition label.
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Typical Osteoporosis enrolment sits around 81 participants.
Median target enrolment is 81 among the 85 trials that report a genuine target (sentinel values excluded). 47 of those (55.3%) plan for fewer than 100 participants.
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Osteoporosis research is mostly interventional.
73 interventional and 14 observational studies make up this index (83.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
87 total, page 2 of 2
Hormone Replacement Therapy to Treat Turner Syndrome
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT00013546
Longitudinal Effects of Denosumab on Trabecular Bone Score and Femur Strength Index
HealthEast Care System
NCT02435147
Vitamin D Supplementation in Obesity and Weight Loss (3DD Study)
Rutgers University
NCT01631292
Parathyroid Hormone (PTH) for Osteoporosis in Postmenopausal Women
Massachusetts General Hospital
NCT00086619
A Comparison Study of PF708 and Forteo in Healthy Subjects
Pfenex
NCT02656810
3-Week Parathyroid Hormone-related Protein (PTHrP) Dose Escalation Study in Post-Menopausal Women
University of Pittsburgh
NCT00222872
Prevention of Bone Loss After Acute SCI by Zoledronic Acid
Northwestern University
NCT02325414
Zoledronate in Treating Osteopenia or Osteoporosis in Postmenopausal Women Receiving Letrozole for Stage I, Stage II, or Stage IIIA Primary Breast Cancer
Mayo Clinic
NCT00436917
Determinants of Bone Mineral Density and Metabolic Syndrome in South Asian Indian Men
Drexel University
NCT03600675
Zoledronate in Preventing Osteoporosis in Patients With Primary Malignant Glioma
Duke University
NCT00301873
Abaloparatide Before Total Knee Arthroplasty
University of Wisconsin, Madison
NCT04167163
Effect of Calcium Supplement Particle Size and Vitamin D Supplement on Calcium Retention in Adolescent Girls
Purdue University
NCT01005381
Alendronate Prevents Microarchitectural Deterioration of Trabecular Bone in Early Postmenopausal Women
University of California, San Francisco
NCT00504166
Effect of Two Exercise Programs on Bone Strength and Architecture
University of Colorado, Denver
NCT02636530
S-32 PG 242 Short Stem
St. Louis Joint Replacement Institute
NCT05083728
Early Effects of Parathyroid Hormone (PTH) on the Proximal Femur
Health Research
NCT01309399
A Safety, Tolerability and Pharmacodynamics Study of ACE-011 (ActRIIA-IgG1) in Healthy Postmenopausal Women
Acceleron Pharma, Inc., a wholly-owned subsidiary of Merck & Co., Inc., Rahway, NJ U
NCT00709540
Intervenous (IV) Zoledronic Acid After Forteo in Postmenopausal Women
The Cleveland Clinic
NCT00361595
Effects of a 12-week Home-based Yoga on Bone and Cardiovascular Health
University of Massachusetts, Lowell
NCT04353700
Pharmacokinetics of a Single 14C-labeled Dose of Risedronate or Alendronate Followed by Once-a-week Unlabeled Oral Dose
Warner Chilcott
NCT00577850
Validation of a Revised Food Frequency Questionnaire
University of Nebraska
NCT02693184
Secondary Prevention of Osteoporosis
Hebrew SeniorLife
NCT00421343
Bone Mineral Density and Cancer Recurrence in Patients With Early Stage Prostate Cancer
University of Medicine and Dentistry of New Jersey
NCT00176579
12 Month Extension Study of the Effect of Teriparatide on Bone in People With Chronic Spinal Cord Injury (SCI)
Northwestern University
NCT02025179
Soluble Corn Fiber and Calcium Utilization in Adolescents
Purdue University
NCT01571440
Evaluation of Outcomes of DFine StabiliT Kyphoplasty in Vertebral Compression Fractures Due to Osteoporosis
Cedars-Sinai Medical Center
NCT01839682
Skeletal Response to Simulated Night Shift
University of Colorado, Denver
NCT05074277
Does Treatment of Hypovitaminosis D Increase Calcium Absorption?
University of Wisconsin, Madison
NCT00581828
Melatonin Osteoporosis Prevention Study
Duquesne University
NCT01152580
One Week Parathyroid Hormone-related Protein (PTHrP) IV Dose Escalation Study
University of Pittsburgh
NCT00580788
Effect of Parathyroid Hormone (PTH) and Weight-Bearing on Bone in Spinal Cord Injury (SCI)
Thomas J. Schnitzer
NCT00826228
PTH And Calcium Responses to Exercise (PACE) in Older Adults
University of Colorado, Denver
NCT02468817
The Effect of Protein on Calcium Absorption and Gastric Acid Production
Yale University
NCT00719160
Effects of Lagenbone on Bone Mineral Density
Southern California University of Health Sciences
NCT04557553
A Study of High-Dose Vit D Versus Standard of Care Vit D Supplementation
Wake Forest University Health Sciences
NCT05016310
Study of Low Bone Mass in Premenopausal or Perimenopausal Women
National Center for Research Resources (NCRR)
NCT00005101
The Relationship Between Vitamin D, Fingernail Thickness and Bone Density
National Center for Research Resources (NCRR)
NCT00006196
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 11 |
| Phase 2 | 10 |
| Phase 3 | 12 |
| Phase 4 | 16 |
Top Sponsors
Named interventions
Most-linked intervention names on Osteoporosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Osteoporosis trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Osteoporosis page
87 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 11 Osteoporosis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Colorado, Denver sponsors the most Osteoporosis trials on record, review their full trial history before evaluating a specific study. See University of Colorado, Denver's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Osteoporosis condition card totals 87 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.