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Open Angle Glaucoma: later-stage trial registry
8 of 30 indexed Open Angle Glaucoma trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #519 of 28,707 conditions by registered trial count.
30 US clinical trials · 8 currently recruiting · #519 of 28,707 conditions by registered trial count
Open Angle Glaucoma: 30 US clinical trials tracked, 8 recruiting.
Open Angle Glaucoma is the subject of 30 registered US clinical trials on ClinicalTrials.gov, 8 of them currently open to new participants. 15 are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most active sponsor is Alcon Research, running 4 of these trials.
Enrollment posture brief
Registry condition open-angle-glaucoma
OPEN 8 | RECR 27% | LATE 15 | EARLY 6 | RANK #519 | SPON 4
Volume-matched condition peers
Nearest open-share peer: Age-related Macular Degeneration (27% recruiting · 75 trials)
Open Angle Glaucoma lists 8 open slots (27% of 30 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Open Angle Glaucoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Open Angle Glaucoma is recruiting below its size-band peers.
8 of 30 indexed trials (26.7%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Open Angle Glaucoma trials is spread across many organizations.
Alcon Research accounts for 4 of 30 trials (13.3%). 24 distinct sponsors appear on at least one study for this condition label.
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Typical Open Angle Glaucoma enrolment sits around 150 participants.
Median target enrolment is 150 among the 29 trials that report a genuine target (sentinel values excluded). 12 of those (41.4%) plan for fewer than 100 participants.
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Open Angle Glaucoma research is mostly interventional.
24 interventional and 6 observational studies make up this index (80% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
30 total, page 1 of 1
Efficacy of Surgical Systems in Combination With Phacoemulsification: a Retrospective Analysis
Barnet Dulaney Perkins Eye Centers
NCT06953349
A Randomized, Double-blind, Parallel-group, Two-arm, Multiple Dose, Multicenter, Bioequivalence Study With Clinical Endpoint in the Treatment of Subjects With Chronic Open-angle Glaucoma or Ocular Hypertension in Both Eyes
Amneal Pharmaceuticals
NCT06267274
Safety and Effectiveness of Minimally Invasive Micro Sclerostomy (MIMS®) to Reduce Intraocular Pressure in Open-Angle Glaucoma Which is Not Controlled Despite Polypharmacy
Sanoculis
NCT06313749
AGN-193408 SR in the Treatment of Open-angle Glaucoma or Ocular Hypertension
AbbVie
NCT04499248
Efficacy of Simbrinza and Rocklatan vs Cosopt and Latanoprost
Prairie Eye Center
NCT06883123
24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients
Mayo Clinic
NCT07325240
Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle Glaucoma
Jonathon Myers
NCT07228221
Biomarkers of Ocular Surface Damage in the Setting of Topical Ocular Hypotensive Medication Use
University of Miami
NCT07217678
Reformulated PG324 Ophthalmic Solution for Intraocular Pressure Reduction
Alcon Research
NCT07082816
Long-term Safety and Efficacy Extension Trial of Bimatoprost SR
AbbVie
NCT03891446
STREAMLINE®SURGICAL SYSTEM Compared to iStent Inject W® in Patients With Open-Angle Glaucoma
New World Medical
NCT05280366
A Study of PER-001 in Participants With Open-Angle Glaucoma
Perfuse Therapeutics
NCT05822245
Comparative Effectiveness of Treatment Strategies for Primary Open-Angle Glaucoma
Agency for Healthcare Research and Quality (AHRQ)
NCT01645319
Evaluation of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma and Ocular Hypertension
Aerie Pharmaceuticals
NCT02207621
Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension
Aerie Pharmaceuticals
NCT02558374
MRCT Evaluating NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension
Nicox Ophthalmics
NCT04630808
Evaluation of Safety and Efficacy of PDP-716
Sun Pharma Advanced Research Company Limited
NCT03450629
A 12-week, Randomized, Double-masked, Parallel Group Comparison of Evening Dosing With Xalacom in Subjects With Glaucoma
Pfizer's Upjohn has merged with Mylan to form Viatris
NCT00277498
Comparing the Safety and Efficacy of BOL-303259-X Ophthalmic Solution With Timolol Maleate Ophthalmic Solution in Subjects With Open-Angle Glaucoma or Ocular Hypertension
Bausch & Lomb Incorporated
NCT01749930
18 Month Prospective Efficacy and Safety Study of Bimatoprost Intracameral Implant (DURYSTA)
Allergan
NCT04647214
Anecortave Acetate Safety in Patients With Open-Angle Glaucoma or Ocular Hypertension
Alcon Research
NCT00691717
Evaluation of Safety of SPARC0913 in Open Angle Glaucoma or Ocular Hypertension
Sun Pharma Advanced Research Company Limited
NCT00945958
A 28 Day Study of ONO-9054 Ophthalmic Solution in Subjects With Ocular Hypertension (OHT) or Open-angle Glaucoma (OAG)
Ono Pharmaceutical Co.
NCT02083289
A Phase IIIb Study of DuoTrav to Treat Glaucoma or Ocular Hypertension
Alcon Research
NCT00465803
Determinants of Compliance With Glaucoma Therapy
University of Alabama at Birmingham
NCT00362622
Diurnal and Nocturnal Effect of Travatan With SofZia Preservative on Intraocular Pressure and Ocular Perfusion Pressure
University of Colorado, Denver
NCT01779778
Effects of Selective Laser Trabeculoplasty on Aqueous Humor Dynamics
University of Nebraska
NCT01342406
Study of ANX007 in Participants With Primary Open-angle Glaucoma
Annexon
NCT04188015
Surgical Treatment of Refractory Open Angle Glaucoma
iScience Interventional Corporation
NCT01212861
Phase 3 Study to Evaluate IOP Lowering Therapy in Open Angle Glaucoma and Ocular Hypertension C-01-70
Alcon Research
NCT00047541
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 2 |
| Phase 3 | 11 |
| Phase 4 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Open Angle Glaucoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Open Angle Glaucoma trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Open Angle Glaucoma page
30 registered trials, 8 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 8 Open Angle Glaucoma trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Alcon Research sponsors the most Open Angle Glaucoma trials on record, review their full trial history before evaluating a specific study. See Alcon Research's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Open Angle Glaucoma condition card totals 30 registered trials; most-linked intervention AR-13324 Ophthalmic Solution 0.02%; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.