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Open Angle Glaucoma
Open-data reference.
16 US clinical trials · 4 currently recruiting
Active & Recent Trials
Safety and Effectiveness of Minimally Invasive Micro Sclerostomy (MIMS®) to Reduce Intraocular Pressure in Open-Angle Glaucoma Which is Not Controlled Despite Polypharmacy
Sanoculis
NCT06313749
Efficacy of Simbrinza and Rocklatan vs Cosopt and Latanoprost
Prairie Eye Center
NCT06883123
24-hour Effect of Rocklatan Compared With Latanoprost in Open Angle Glaucoma and Ocular Hypertension Patients
Mayo Clinic
NCT07325240
Standalone iStent Infinite and iDose TR for Management of Moderate to Severe Open Angle Glaucoma
Jonathon Myers
NCT07228221
Reformulated PG324 Ophthalmic Solution for Intraocular Pressure Reduction
Alcon Research
NCT07082816
STREAMLINE®SURGICAL SYSTEM Compared to iStent Inject W® in Patients With Open-Angle Glaucoma
New World Medical
NCT05280366
Comparative Effectiveness of Treatment Strategies for Primary Open-Angle Glaucoma
Agency for Healthcare Research and Quality (AHRQ)
NCT01645319
MRCT Evaluating NCX 470 vs. Latanoprost in Subjects With Open-Angle Glaucoma or Ocular Hypertension
Nicox Ophthalmics
NCT04630808
Evaluation of Safety and Efficacy of PDP-716
Sun Pharma Advanced Research Company Limited
NCT03450629
A 12-week, Randomized, Double-masked, Parallel Group Comparison of Evening Dosing With Xalacom in Subjects With Glaucoma
Pfizer's Upjohn has merged with Mylan to form Viatris
NCT00277498
Evaluation of Safety of SPARC0913 in Open Angle Glaucoma or Ocular Hypertension
Sun Pharma Advanced Research Company Limited
NCT00945958
Determinants of Compliance With Glaucoma Therapy
University of Alabama at Birmingham
NCT00362622
Diurnal and Nocturnal Effect of Travatan With SofZia Preservative on Intraocular Pressure and Ocular Perfusion Pressure
University of Colorado, Denver
NCT01779778
Effects of Selective Laser Trabeculoplasty on Aqueous Humor Dynamics
University of Nebraska
NCT01342406
Study of ANX007 in Participants With Primary Open-angle Glaucoma
Annexon
NCT04188015
Surgical Treatment of Refractory Open Angle Glaucoma
iScience Interventional Corporation
NCT01212861
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 1 |
| Phase 3 | 5 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Open Angle Glaucoma Trial Landscape
ClinicalTrials.gov lists 16 US studies indexed under Open Angle Glaucoma, and 4 of those are currently open to recruitment — roughly 25% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Open Angle Glaucoma shows 8 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Open Angle Glaucoma is led by Sun Pharma Advanced Research Company Limited with 2 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 16 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Open Angle Glaucoma?
PlainTrial tracks 16 US clinical trials for Open Angle Glaucoma, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Open Angle Glaucoma?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.