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Study of ANX007 in Participants With Primary Open-angle Glaucoma
NCT04188015 · View on ClinicalTrials.gov ↗
Study Summary
This is a double-masked, randomized, sham-controlled study evaluating two dose levels of ANX007 vs sham, administered as repeat Intravitreal (IVT) injections in patients with Primary Open-angle Glaucoma.
Conditions Studied
Interventions
- OTHER Sham Procedure
- BIOLOGICAL 2.5mg ANX007
- BIOLOGICAL 5.0mg ANX007
Study Locations (2)
California
- Eye Research Foundation — Newport Beach
- Stanford Health Care — Stanford
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 17 participants |
| Start Date | 2018-07-25 |
| Est. Completion | 2019-06-03 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT04188015
The ClinicalTrials.gov registry entry for NCT04188015 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 17 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Annexon, which has 35 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 1 condition, with Open Angle Glaucoma appearing as the primary indexed condition, and to 3 interventions — of which Sham Procedure is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT04188015 reports 2 study locations spanning 1 distinct geographic area — top geographies include California. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT04188015 about?
NCT04188015 is a clinical study titled "Study of ANX007 in Participants With Primary Open-angle Glaucoma". This is a double-masked, randomized, sham-controlled study evaluating two dose levels of ANX007 vs sham, administered as repeat Intravitreal (IVT) injections in patients with Primary Open-angle Glaucoma.
What is the current status of trial NCT04188015?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 17 participants. The study started on 2018-07-25. Estimated completion is 2019-06-03.
What conditions does trial NCT04188015 study?
This clinical trial studies the following conditions: Open Angle Glaucoma. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT04188015?
The interventions under investigation include: Sham Procedure (OTHER), 2.5mg ANX007 (BIOLOGICAL), 5.0mg ANX007 (BIOLOGICAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT04188015?
This trial is sponsored by Annexon, which has 35 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT04188015 being conducted?
This trial has 2 study locations across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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