Aerie Pharmaceuticals

32 total trials 32 completed

Aerie Pharmaceuticals sponsors 32 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 32 completed. 11 of these trials are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Dry Eye Disease, with 2 trials.

Trial Pipeline

32 total, page 1 of 1

COMPLETED Phase 3

A Long-Term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512

NCT05493111

COMPLETED Phase 3

Study Evaluating the Safety and Efficacy of AR-15512 (COMET-3)

NCT05360966

COMPLETED Phase 3

Study Evaluating the Safety and Efficacy of AR-15512

NCT05285644

COMPLETED Phase 4

Rocklatan® Evaluation

NCT05283395

COMPLETED Phase 1

Study Evaluating Techniques for Measuring Tear Production

NCT05497479

COMPLETED Phase 2

A Phase 2b Study Evaluating the Safety and Efficacy of AR-15512 Ophthalmic Solution for the Treatment of Dry Eye Disease

NCT04498182

COMPLETED Phase 2

A Phase 2 Study Evaluating the Safety and Efficacy of Netarsudil Ophthalmic Solution in Patients With Corneal Edema Due to Fuchs Corneal Dystrophy

NCT04498169

COMPLETED Phase 1

A Study Assessing AR-13503 Implant in Subjects With nAMD or DME

NCT03835884

COMPLETED Phase 2

Study Assessing AR-1105 in Subjects With Macular Edema Due to Retinal Vein Occlusion (RVO)

NCT03739593

COMPLETED Phase 4

Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Setting

NCT03808688

COMPLETED Phase 2

Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension

NCT03310580

COMPLETED Phase 2

Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)

NCT03233308

COMPLETED Phase 2

Nocturnal/Diurnal Intraocular Pressure-Lowering Effect of Netarsudil Ophthalmic Solution

NCT02874846

COMPLETED Phase 3

Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension

NCT02674854

COMPLETED Phase 3

Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

NCT02558400

COMPLETED Phase 3

Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension

NCT02558374

COMPLETED Phase 1

A Controlled Study of the Aqueous Humor Dynamics of AR-13324 Ophthalmic Solution in Healthy Adult Volunteers

NCT02406287

COMPLETED Phase 3

Study of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

NCT02246764

COMPLETED Phase 3

Evaluation of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma and Ocular Hypertension

NCT02207621

COMPLETED Phase 3

Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension

NCT02207491

COMPLETED Phase 2

Study Assessing Safety and Efficacy of PG324 Ophthalmic Solution in Patients With Elevated Intraocular Pressure

NCT02057575

COMPLETED Phase 1

Study Assessing Ocular and Systemic Safety of AR-13324 in Healthy Volunteers

NCT01997879

COMPLETED Phase 2

A Study Assessing PG286 Ophthalmic Solution, 0.5% Compared to Its Individual Components for 28 Days

NCT01789736

COMPLETED Phase 2

Study Comparing the Safety and Efficacy of AR-13324 to Latanoprost in Patients With Elevated Intraocular Pressure

NCT01731002

COMPLETED Phase 2

Study of AR-13324 in Patients With Elevated Intraocular Pressure

NCT01528787

COMPLETED Phase 2

AR-12286 Fixed Dose Combination to Lower Elevated Intraocular Pressure

NCT01474135

COMPLETED Phase 2

24-hour Efficacy of AR-12286

NCT01330979

COMPLETED Phase 2

AR-12286 in Combination With Latanoprost

NCT01302249

COMPLETED Phase 1

Formulation Comparison in Normal Volunteers

NCT01250197

COMPLETED Phase 2

Study of AR-12286 Versus Latanoprost in Patients With Elevated Intraocular Pressure

NCT01060579

COMPLETED Phase 2

A Study of AR-12286 in Patient With Elevated Intraocular Pressure (IOP)

NCT00902200

COMPLETED Phase 2

Ocular Hypotensive Efficacy of AR-102

NCT00523250

Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 16
Phase 3 9
Phase 4 2

What the Pipeline for Aerie Pharmaceuticals Shows

According to the ClinicalTrials.gov registry, Aerie Pharmaceuticals is linked to 32 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 32 are already marked complete, representing roughly 100% of the total.

The phase mix for Aerie Pharmaceuticals reports 11 late-stage studies (Phase 3 and Phase 4 combined) and 21 earlier-phase studies (Phase 1 and Phase 2).

The top therapeutic focus area indexed for Aerie Pharmaceuticals is Dry Eye Disease with 2 linked trials, and 6 other condition areas appear in the top list above.

How to read these pipeline numbers

Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.

A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.

That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.