Aerie Pharmaceuticals
Aerie Pharmaceuticals sponsors 32 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 32 completed. 11 of these trials are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Dry Eye Disease, with 2 trials.
Trial Pipeline
32 total, page 1 of 1
A Long-Term Safety Study Evaluating the Safety and Systemic Exposure of AR-15512
NCT05493111
Study Evaluating the Safety and Efficacy of AR-15512 (COMET-3)
NCT05360966
Study Evaluating the Safety and Efficacy of AR-15512
NCT05285644
Rocklatan® Evaluation
NCT05283395
Study Evaluating Techniques for Measuring Tear Production
NCT05497479
A Phase 2b Study Evaluating the Safety and Efficacy of AR-15512 Ophthalmic Solution for the Treatment of Dry Eye Disease
NCT04498182
A Phase 2 Study Evaluating the Safety and Efficacy of Netarsudil Ophthalmic Solution in Patients With Corneal Edema Due to Fuchs Corneal Dystrophy
NCT04498169
A Study Assessing AR-13503 Implant in Subjects With nAMD or DME
NCT03835884
Study Assessing AR-1105 in Subjects With Macular Edema Due to Retinal Vein Occlusion (RVO)
NCT03739593
Study of Rhopressa® for the Reduction of Elevated Intraocular Pressure in Patients With Glaucoma or Ocular Hypertension in a Real-world Setting
NCT03808688
Study of Netarsudil Ophthalmic Solution in Japanese/Japanese-American Subjects With Open-angle Glaucoma or Ocular Hypertension
NCT03310580
Study of Netarsudil Ophthalmic Solution in Subjects With Primary Open Angle Glaucoma (POAG) or Ocular Hypertension (OHT)
NCT03233308
Nocturnal/Diurnal Intraocular Pressure-Lowering Effect of Netarsudil Ophthalmic Solution
NCT02874846
Double-masked Study of PG324 Ophthalmic Solution in Patients With Open-angle Glaucoma or Ocular Hypertension
NCT02674854
Double-masked Study of PG324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
NCT02558400
Double-masked Study of Netarsudil (AR-13324) Ophthalmic Solution in Subjects With Glaucoma or Ocular Hypertension
NCT02558374
A Controlled Study of the Aqueous Humor Dynamics of AR-13324 Ophthalmic Solution in Healthy Adult Volunteers
NCT02406287
Study of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
NCT02246764
Evaluation of Netarsudil (AR-13324) Ophthalmic Solution in Patients With Glaucoma and Ocular Hypertension
NCT02207621
Double-masked Study of AR-13324 Ophthalmic Solution in Patients With Glaucoma or Ocular Hypertension
NCT02207491
Study Assessing Safety and Efficacy of PG324 Ophthalmic Solution in Patients With Elevated Intraocular Pressure
NCT02057575
Study Assessing Ocular and Systemic Safety of AR-13324 in Healthy Volunteers
NCT01997879
A Study Assessing PG286 Ophthalmic Solution, 0.5% Compared to Its Individual Components for 28 Days
NCT01789736
Study Comparing the Safety and Efficacy of AR-13324 to Latanoprost in Patients With Elevated Intraocular Pressure
NCT01731002
Study of AR-13324 in Patients With Elevated Intraocular Pressure
NCT01528787
AR-12286 Fixed Dose Combination to Lower Elevated Intraocular Pressure
NCT01474135
24-hour Efficacy of AR-12286
NCT01330979
AR-12286 in Combination With Latanoprost
NCT01302249
Formulation Comparison in Normal Volunteers
NCT01250197
Study of AR-12286 Versus Latanoprost in Patients With Elevated Intraocular Pressure
NCT01060579
A Study of AR-12286 in Patient With Elevated Intraocular Pressure (IOP)
NCT00902200
Ocular Hypotensive Efficacy of AR-102
NCT00523250
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 16 |
| Phase 3 | 9 |
| Phase 4 | 2 |
Therapeutic Areas
What the Pipeline for Aerie Pharmaceuticals Shows
According to the ClinicalTrials.gov registry, Aerie Pharmaceuticals is linked to 32 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 32 are already marked complete, representing roughly 100% of the total.
The phase mix for Aerie Pharmaceuticals reports 11 late-stage studies (Phase 3 and Phase 4 combined) and 21 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Aerie Pharmaceuticals is Dry Eye Disease with 2 linked trials, and 6 other condition areas appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.