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ClinicalTrials.gov 18 recruiting now later-stage tilt

Cognition: later-stage trial registry

18 of 36 indexed Cognition trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #419 of 28,707 conditions by registered trial count.

36 US clinical trials · 18 currently recruiting · #419 of 28,707 conditions by registered trial count

Cognition: 36 US clinical trials tracked, 18 recruiting.

Cognition is the subject of 36 registered US clinical trials on ClinicalTrials.gov, 18 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Georgia State University, running 3 of these trials.

Enrollment posture brief

Registry condition cognition

OPEN 18 | RECR 50% | LATE 2 | EARLY 1 | RANK #419 | SPON 3

Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)

Dysphagia63.9%Huntington Disease50%Cognition (this)50%Chronic Myeloid Leukemia38.9%Coronary Disease2.8%
Open-enrollment share among volume-matched conditions near Cognition

Cognition lists 18 open slots (50% of 36 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Cognition on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Cognition is recruiting above its size-band peers.

    18 of 36 indexed trials (50%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Cognition trials is spread across many organizations.

    Georgia State University accounts for 3 of 36 trials (8.3%). 31 distinct sponsors appear on at least one study for this condition label.

  3. Most Cognition trials plan to enrol fewer than 100 people.

    Median target enrolment is 80 among the 36 trials that report a genuine target (sentinel values excluded). 24 of those (66.7%) plan for fewer than 100 participants.

  4. Cognition research is mostly interventional.

    31 interventional and 5 observational studies make up this index (86.1% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 21Phase 32

Open and recent trials

36 total, page 1 of 1

RECRUITING 1,000 participants

Tennessee Alzheimer's Project

Vanderbilt University Medical Center

NCT05372172

RECRUITING NA 422 participants

A Clinical Trial to Assess Cognitive Effects of Cognitive Nutritional Supplement in General Population

Pharmavite

NCT06837246

RECRUITING NA 220 participants

Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury

Wake Forest University Health Sciences

NCT04810858

RECRUITING NA 128 participants

Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome

Hebrew SeniorLife

NCT06821568

RECRUITING Phase 3 103 participants

Cognitive Strategies in Early Psychosis 1

University of Minnesota

NCT07231497

RECRUITING NA 100 participants

Nutrition to Support Postoperative Recovery

Dartmouth-Hitchcock Medical Center

NCT07109505

RECRUITING NA 100 participants

Integrated Childhood Activity AND Nutrition (ican) Study

University of Illinois at Urbana-Champaign

NCT07011602

RECRUITING NA 80 participants

The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study

University of Florida

NCT05090267

RECRUITING NA 80 participants

A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers

University of Kansas Medical Center

NCT06667661

RECRUITING NA 80 participants

Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure

Georgia State University

NCT06735599

RECRUITING NA 72 participants

Peanuts for Cardiometabolic, Brain, and Intestinal Health

Georgia State University

NCT06867198

RECRUITING NA 63 participants

Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSD

VA Office of Research and Development

NCT05380050

RECRUITING NA 50 participants

Identifying the Neural Correlates of Mental Simulation in Multi-Step Planning

New York University

NCT07293637

RECRUITING NA 50 participants

Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters

California Polytechnic State University-San Luis Obispo

NCT07477184

RECRUITING NA 30 participants

The Effect of Near-infrared Light Therapy on Brain Function and Cognition in Young and Older Adults

University of Oklahoma

NCT07209683

RECRUITING NA 30 participants

Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes

Georgia State University

NCT06735651

RECRUITING NA 20 participants

The Impact of Whey Protein on Frailty in Older Adults Classified as Pre-frail

University of Kansas Medical Center

NCT07167277

RECRUITING NA 16 participants

Cognitive Vitality Pilot Study

Arizona State University

NCT07208279

ACTIVE NOT RECRUITING NA 816 participants

Brain Response to an Intervention Using Guided, At-Home Technology for the Mind

Lumos Labs

NCT05912556

ACTIVE NOT RECRUITING NA 97 participants

Trial of Pistachio Consumption in Older Adults

Brigham and Women's Hospital

NCT06992544

ACTIVE NOT RECRUITING NA 82 participants

Partnered Dance Aerobic Exercise as a Neuroprotective, Motor and Cognitive Intervention in Parkinson's Disease

VA Office of Research and Development

NCT04122690

ACTIVE NOT RECRUITING NA 69 participants

EndeavorOTC® Research Study in College Students

Akili Interactive Labs

NCT06376032

COMPLETED 1,271 participants

D2D Normative Data for Remote Assessments

University of Minnesota

NCT03206775

COMPLETED Phase 2 317 participants

Safety and Cognitive Function Study of EVP-6124 in Patients With Schizophrenia

FORUM Pharmaceuticals

NCT00968851

COMPLETED NA 159 participants

Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT01212029

COMPLETED Phase 3 100 participants

Exercise, Executive Processes and the Aging Brain

National Institute on Aging (NIA)

NCT00430976

COMPLETED 97 participants

The Benefits of Nature for Mood and Cognition in Persons With and Without Parkinson's Disease

Boston University Charles River Campus

NCT06483126

COMPLETED NA 85 participants

Bio-Experiential Spaces for Mental Health in Healthworkers

Icahn School of Medicine at Mount Sinai

NCT05227352

COMPLETED 68 participants

Nutrition, Physical Activity, and Cognition in Breast Cancer Survivors

Texas State University, San Marcos

NCT02591316

COMPLETED NA 40 participants

Impacts of Fruit on the Gut Health and Human Health

San Diego State University

NCT05063929

COMPLETED 40 participants

Neurocognitive Effects of Buprenorphine Among HIV+ and HIV-Opioid Users

Albert Einstein College of Medicine

NCT01108679

COMPLETED NA 35 participants

Support for Caregivers of Older Adults With Cognitive Decline

State University of New York at Buffalo

NCT04787068

COMPLETED NA 31 participants

Effect of Daily Walnut Consumption on Memory in Subjects With Long-COVID

University of California, Los Angeles

NCT07429903

COMPLETED NA 31 participants

Emerging From the Haze™- Measuring the Impact of a Psycho-education Program on Perceived Cognition After Breast Cancer Treatment

Cedars-Sinai Medical Center

NCT02360917

COMPLETED NA 16 participants

Acute Exercise on Brain Insulin Sensitivity

Rutgers, The State University of New Jersey

NCT05853913

COMPLETED NA 10 participants

Optimizing Sleep/Wake Related Cognitive Efficacy

Mayo Clinic

NCT02412410

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 3 2

Named interventions

Most-linked intervention names on Cognition records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Dietary supplement
3 trials
Wild Blueberry Dietary supplement
2 trials
Minds in Motion Behavioral
1 trials
Occupational Therapy support Behavioral
1 trials
Fatigue avoidance education Behavioral
1 trials
Emerging from the Haze Other
1 trials
Cognitive Battery C (Phase 2) Behavioral
1 trials
Cognitive Battery B (Phase 2) Behavioral
1 trials

US sites by state

Facility locations filed on Cognition trials. A trial with sites in several states counts in each.

California 7 trials
New York 5 trials
Illinois 4 trials
Georgia 4 trials
Florida 4 trials
Minnesota 3 trials
Massachusetts 3 trials
Texas 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Cognition page

36 registered trials, 18 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Cognition condition card totals 36 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.