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Cognition
Open-data reference.
36 US clinical trials · 18 currently recruiting
Active & Recent Trials
Tennessee Alzheimer's Project
Vanderbilt University Medical Center
NCT05372172
A Clinical Trial to Assess Cognitive Effects of Cognitive Nutritional Supplement in General Population
Pharmavite
NCT06837246
Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury
Wake Forest University Health Sciences
NCT04810858
Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome
Hebrew SeniorLife
NCT06821568
Cognitive Strategies in Early Psychosis 1
University of Minnesota
NCT07231497
Nutrition to Support Postoperative Recovery
Dartmouth-Hitchcock Medical Center
NCT07109505
INTEGRATED CHILDHOOD ACTIVITY AND NUTRITION (ICAN) STUDY
University of Illinois at Urbana-Champaign
NCT07011602
The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study
University of Florida
NCT05090267
A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers
University of Kansas Medical Center
NCT06667661
Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure
Georgia State University
NCT06735599
Peanuts for Cardiometabolic, Brain, and Intestinal Health
Georgia State University
NCT06867198
Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSD
VA Office of Research and Development
NCT05380050
Identifying the Neural Correlates of Mental Simulation in Multi-Step Planning
New York University
NCT07293637
Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters
California Polytechnic State University-San Luis Obispo
NCT07477184
The Effect of Near-infrared Light Therapy on Brain Function and Cognition in Young and Older Adults
University of Oklahoma
NCT07209683
Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes
Georgia State University
NCT06735651
The Impact of Whey Protein on Frailty in Older Adults Classified as Pre-frail
University of Kansas Medical Center
NCT07167277
Cognitive Vitality Pilot Study
Arizona State University
NCT07208279
Brain Response to an Intervention Using Guided, At-Home Technology for the Mind
Lumos Labs
NCT05912556
Trial of Pistachio Consumption in Older Adults
Brigham and Women's Hospital
NCT06992544
Partnered Dance Aerobic Exercise as a Neuroprotective, Motor and Cognitive Intervention in Parkinson's Disease
VA Office of Research and Development
NCT04122690
EndeavorOTC® Research Study in College Students
Akili Interactive Labs
NCT06376032
D2D Normative Data for Remote Assessments
University of Minnesota
NCT03206775
Safety and Cognitive Function Study of EVP-6124 in Patients With Schizophrenia
FORUM Pharmaceuticals
NCT00968851
Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NCT01212029
Exercise, Executive Processes and the Aging Brain
National Institute on Aging (NIA)
NCT00430976
The Benefits of Nature for Mood and Cognition in Persons With and Without Parkinson's Disease
Boston University Charles River Campus
NCT06483126
Bio-Experiential Spaces for Mental Health in Healthworkers
Icahn School of Medicine at Mount Sinai
NCT05227352
Nutrition, Physical Activity, and Cognition in Breast Cancer Survivors
Texas State University, San Marcos
NCT02591316
Impacts of Fruit on the Gut Health and Human Health
San Diego State University
NCT05063929
Neurocognitive Effects of Buprenorphine Among HIV+ and HIV-Opioid Users
Albert Einstein College of Medicine
NCT01108679
Support for Caregivers of Older Adults With Cognitive Decline
State University of New York at Buffalo
NCT04787068
Effect of Daily Walnut Consumption on Memory in Subjects With Long-COVID
University of California, Los Angeles
NCT07429903
Emerging From the Haze™- Measuring the Impact of a Psycho-education Program on Perceived Cognition After Breast Cancer Treatment
Cedars-Sinai Medical Center
NCT02360917
Acute Exercise on Brain Insulin Sensitivity
Rutgers, The State University of New Jersey
NCT05853913
Optimizing Sleep/Wake Related Cognitive Efficacy
Mayo Clinic
NCT02412410
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
| Phase 3 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Cognition Trial Landscape
ClinicalTrials.gov lists 36 US studies indexed under Cognition, and 18 of those are currently open to recruitment — roughly 50% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Cognition shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Cognition is led by Georgia State University with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 36 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Cognition?
PlainTrial tracks 36 US clinical trials for Cognition, of which 18 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Cognition?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.