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2026 data Public-data reference. official source

Cognition

Open-data reference.

36 US clinical trials · 18 currently recruiting

Active & Recent Trials

RECRUITING 1,000 participants

Tennessee Alzheimer's Project

Vanderbilt University Medical Center

NCT05372172

RECRUITING NA 422 participants

A Clinical Trial to Assess Cognitive Effects of Cognitive Nutritional Supplement in General Population

Pharmavite

NCT06837246

RECRUITING NA 220 participants

Modeling the Effects of Chronic Marijuana Use on Neuroinflammation and HIV-related Neuronal Injury

Wake Forest University Health Sciences

NCT04810858

RECRUITING NA 128 participants

Home-Based Brain Stimulation for Motoric Cognitive Risk Syndrome

Hebrew SeniorLife

NCT06821568

RECRUITING Phase 3 103 participants

Cognitive Strategies in Early Psychosis 1

University of Minnesota

NCT07231497

RECRUITING NA 100 participants

Nutrition to Support Postoperative Recovery

Dartmouth-Hitchcock Medical Center

NCT07109505

RECRUITING NA 100 participants

INTEGRATED CHILDHOOD ACTIVITY AND NUTRITION (ICAN) STUDY

University of Illinois at Urbana-Champaign

NCT07011602

RECRUITING NA 80 participants

The Path Study: Cognitive and Inflammation Targeted Gut-brain Interventions in Alcohol; Probiotics, Alcohol, Transcutaneous Vagus Nerve Stimulation, and HIV Study

University of Florida

NCT05090267

RECRUITING NA 80 participants

A Mobile App to Improve 24-Hour Movement Guideline Adherence in Preschoolers

University of Kansas Medical Center

NCT06667661

RECRUITING NA 80 participants

Wild Blueberries for Gut, Brain, and Heart Health in Adults With High Blood Pressure

Georgia State University

NCT06735599

RECRUITING NA 72 participants

Peanuts for Cardiometabolic, Brain, and Intestinal Health

Georgia State University

NCT06867198

RECRUITING NA 63 participants

Comparing Telehealth to In-person a Combined Metacognitive Training in Veterans With mTBI/PTSD

VA Office of Research and Development

NCT05380050

RECRUITING NA 50 participants

Identifying the Neural Correlates of Mental Simulation in Multi-Step Planning

New York University

NCT07293637

RECRUITING NA 50 participants

Sleep Well Firefighters: An App-based Program to Improve Sleep, Cognition, and Behavioral Health in Firefighters

California Polytechnic State University-San Luis Obispo

NCT07477184

RECRUITING NA 30 participants

The Effect of Near-infrared Light Therapy on Brain Function and Cognition in Young and Older Adults

University of Oklahoma

NCT07209683

RECRUITING NA 30 participants

Wild Blueberries for Gut, Brain, and Cardiometabolic Health in Prediabetes

Georgia State University

NCT06735651

RECRUITING NA 20 participants

The Impact of Whey Protein on Frailty in Older Adults Classified as Pre-frail

University of Kansas Medical Center

NCT07167277

RECRUITING NA 16 participants

Cognitive Vitality Pilot Study

Arizona State University

NCT07208279

ACTIVE NOT RECRUITING NA 816 participants

Brain Response to an Intervention Using Guided, At-Home Technology for the Mind

Lumos Labs

NCT05912556

ACTIVE NOT RECRUITING NA 97 participants

Trial of Pistachio Consumption in Older Adults

Brigham and Women's Hospital

NCT06992544

ACTIVE NOT RECRUITING NA 82 participants

Partnered Dance Aerobic Exercise as a Neuroprotective, Motor and Cognitive Intervention in Parkinson's Disease

VA Office of Research and Development

NCT04122690

ACTIVE NOT RECRUITING NA 69 participants

EndeavorOTC® Research Study in College Students

Akili Interactive Labs

NCT06376032

COMPLETED 1,271 participants

D2D Normative Data for Remote Assessments

University of Minnesota

NCT03206775

COMPLETED Phase 2 317 participants

Safety and Cognitive Function Study of EVP-6124 in Patients With Schizophrenia

FORUM Pharmaceuticals

NCT00968851

COMPLETED NA 159 participants

Testing and Calibration of Non-Invasive Optical Imaging Technology for Functional Brain Imaging

Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)

NCT01212029

COMPLETED Phase 3 100 participants

Exercise, Executive Processes and the Aging Brain

National Institute on Aging (NIA)

NCT00430976

COMPLETED 97 participants

The Benefits of Nature for Mood and Cognition in Persons With and Without Parkinson's Disease

Boston University Charles River Campus

NCT06483126

COMPLETED NA 85 participants

Bio-Experiential Spaces for Mental Health in Healthworkers

Icahn School of Medicine at Mount Sinai

NCT05227352

COMPLETED 68 participants

Nutrition, Physical Activity, and Cognition in Breast Cancer Survivors

Texas State University, San Marcos

NCT02591316

COMPLETED NA 40 participants

Impacts of Fruit on the Gut Health and Human Health

San Diego State University

NCT05063929

COMPLETED 40 participants

Neurocognitive Effects of Buprenorphine Among HIV+ and HIV-Opioid Users

Albert Einstein College of Medicine

NCT01108679

COMPLETED NA 35 participants

Support for Caregivers of Older Adults With Cognitive Decline

State University of New York at Buffalo

NCT04787068

COMPLETED NA 31 participants

Effect of Daily Walnut Consumption on Memory in Subjects With Long-COVID

University of California, Los Angeles

NCT07429903

COMPLETED NA 31 participants

Emerging From the Haze™- Measuring the Impact of a Psycho-education Program on Perceived Cognition After Breast Cancer Treatment

Cedars-Sinai Medical Center

NCT02360917

COMPLETED NA 16 participants

Acute Exercise on Brain Insulin Sensitivity

Rutgers, The State University of New Jersey

NCT05853913

COMPLETED NA 10 participants

Optimizing Sleep/Wake Related Cognitive Efficacy

Mayo Clinic

NCT02412410

Phase Distribution

PhaseTrial count
Phase 2 1
Phase 3 2

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Cognition Trial Landscape

ClinicalTrials.gov lists 36 US studies indexed under Cognition, and 18 of those are currently open to recruitment — roughly 50% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Cognition shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Cognition is led by Georgia State University with 3 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 36 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Cognition?

PlainTrial tracks 36 US clinical trials for Cognition, of which 18 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Cognition?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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