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Multiple Sclerosis clinical trials
120 of 317 indexed Multiple Sclerosis trials are currently recruiting.
317 US clinical trials · 120 currently recruiting
Multiple Sclerosis is the subject of 317 registered US clinical trials on ClinicalTrials.gov, 120 of them currently open to new participants. 41 are in Phase 3-4 (later-stage) and 74 in Phase 1-2 (earlier-stage). The most active sponsor is Biogen, running 13 of these trials.
The research picture
Multiple Sclerosis has 317 registered US clinical trials, 120 of them open to new participants right now, about 38% of the total.
- 120
- recruiting participants now
- 38%
- of trials open to enrollment
- 41
- in Phase 3–4 (later-stage)
- 13
- top sponsor: Biogen
Active & Recent Trials
317 total, page 7 of 7
LoveYourBrain Yoga for Multiple Sclerosis
Dartmouth-Hitchcock Medical Center
NCT03827928
Thyroid Hormone for Remyelination in Multiple Sclerosis (MS): A Safety and Dose Finding Study
Oregon Health and Science University
NCT02760056
Low Load Resistance Training Using Blood Flow Restriction for People With Multiple Sclerosis
University of Colorado, Denver
NCT04633759
In Vivo Characterization of Inflammation With Ferumoxytol, an Ultrasmall Superparamagnetic Iron Oxide Nanoparticle, on 7 Tesla Magnetic Resonance Imaging
National Institute of Neurological Disorders and Stroke (NINDS)
NCT02511028
Collection of Blood Samples From Patients With Relapsing MS Who Developed ITP After Receiving Lemtrada
Genzyme, a Sanofi Company
NCT03784898
A Study to Analyze the Effect of Acupuncture on Mobility And Quality of Life in Multiple Sclerosis
NYU Langone Health
NCT03174379
Central Nervous System Changes Following OnabotulinumtoxinA Injection in the Bladder
The Methodist Hospital Research Institute
NCT03033355
Wearable Lower Extremity Exoskeleton to Promote Walking in Persons With Multiple Sclerosis
The University of Texas Health Science Center, Houston
NCT02519244
Novel Imaging Markers in SPMS
University of Utah
NCT05357833
A Comparison of an Implanted Neuroprosthesis With Sensory Training for Improving Airway Protection in Chronic Dysphagia
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00376506
Comparison of the Efficacy and Mechanisms for MBCT and CT for Multiple Sclerosis (MS) Chronic Pain
University of Washington
NCT02012439
Constraint-Induced (CI) Movement Therapy for Progressive Multiple Sclerosis (MS)
National Multiple Sclerosis Society
NCT00695084
Impact of Direct Current Electrical Stimulation on Spasticity Levels and Functional Muscle Use in MS
CommonSpirit Health
NCT04942938
Outcomes of Group Dance and Movement Training in Ambulatory MS Patients
GroundWorks DanceTheater
NCT05943145
Quantitative Magnetic Resonance Imaging (MRI) Sub-Study of MS PATHS
Biogen
NCT04145284
Impact of Custom Assistive and Adaptive Technology in Rehabilitation
Madonna Rehabilitation Hospital
NCT03567239
Yoga: Effect on Attention in Aging & Multiple Sclerosis
National Center for Complementary and Integrative Health (NCCIH)
NCT00010998
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 41 |
| Phase 2 | 33 |
| Phase 3 | 24 |
| Phase 4 | 17 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Multiple Sclerosis Trial Landscape
317 indexed Multiple Sclerosis studies · 120 recruiting (38%).
Phase mix: 41 late (III/IV) vs 74 early (I/II).
Top sponsor: Biogen (13 trials), 9 others listed. 17 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Multiple Sclerosis?
PlainTrial tracks 317 US clinical trials for Multiple Sclerosis, of which 120 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Multiple Sclerosis?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.