Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Multiple Sclerosis: early-phase trial registry
120 of 317 indexed Multiple Sclerosis trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #24 of 28,707 conditions by registered trial count.
317 US clinical trials · 120 currently recruiting · #24 of 28,707 conditions by registered trial count
Multiple Sclerosis: 317 US clinical trials tracked, 120 recruiting.
Multiple Sclerosis is the subject of 317 registered US clinical trials on ClinicalTrials.gov, 120 of them currently open to new participants. 41 are in Phase 3-4 (later-stage) and 74 in Phase 1-2 (earlier-stage). The most active sponsor is Biogen, running 13 of these trials.
Enrollment posture brief
Registry condition multiple-sclerosis
OPEN 120 | RECR 38% | LATE 41 | EARLY 74 | RANK #24 | SPON 13
Volume-matched condition peers
Nearest open-share peer: Multiple Myeloma (38% recruiting · 441 trials)
Multiple Sclerosis lists 120 open slots (38% of 317 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Multiple Sclerosis on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Multiple Sclerosis recruits in line with its size-band peers.
120 of 317 indexed trials (37.9%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Multiple Sclerosis trials is spread across many organizations.
Biogen accounts for 13 of 317 trials (4.1%). 142 distinct sponsors appear on at least one study for this condition label.
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Typical Multiple Sclerosis enrolment sits around 61 participants.
Median target enrolment is 61 among the 316 trials that report a genuine target (sentinel values excluded). 181 of those (57.3%) plan for fewer than 100 participants.
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Multiple Sclerosis research is mostly interventional.
231 interventional and 86 observational studies make up this index (72.9% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
317 total, page 7 of 7
LoveYourBrain Yoga for Multiple Sclerosis
Dartmouth-Hitchcock Medical Center
NCT03827928
Thyroid Hormone for Remyelination in Multiple Sclerosis (MS): A Safety and Dose Finding Study
Oregon Health and Science University
NCT02760056
Low Load Resistance Training Using Blood Flow Restriction for People With Multiple Sclerosis
University of Colorado, Denver
NCT04633759
In Vivo Characterization of Inflammation With Ferumoxytol, an Ultrasmall Superparamagnetic Iron Oxide Nanoparticle, on 7 Tesla Magnetic Resonance Imaging
National Institute of Neurological Disorders and Stroke (NINDS)
NCT02511028
Collection of Blood Samples From Patients With Relapsing MS Who Developed ITP After Receiving Lemtrada
Genzyme, a Sanofi Company
NCT03784898
A Study to Analyze the Effect of Acupuncture on Mobility And Quality of Life in Multiple Sclerosis
NYU Langone Health
NCT03174379
Central Nervous System Changes Following OnabotulinumtoxinA Injection in the Bladder
The Methodist Hospital Research Institute
NCT03033355
Wearable Lower Extremity Exoskeleton to Promote Walking in Persons With Multiple Sclerosis
The University of Texas Health Science Center, Houston
NCT02519244
Novel Imaging Markers in SPMS
University of Utah
NCT05357833
A Comparison of an Implanted Neuroprosthesis With Sensory Training for Improving Airway Protection in Chronic Dysphagia
National Institute of Neurological Disorders and Stroke (NINDS)
NCT00376506
Comparison of the Efficacy and Mechanisms for MBCT and CT for Multiple Sclerosis (MS) Chronic Pain
University of Washington
NCT02012439
Constraint-Induced (CI) Movement Therapy for Progressive Multiple Sclerosis (MS)
National Multiple Sclerosis Society
NCT00695084
Impact of Direct Current Electrical Stimulation on Spasticity Levels and Functional Muscle Use in MS
CommonSpirit Health
NCT04942938
Outcomes of Group Dance and Movement Training in Ambulatory MS Patients
GroundWorks DanceTheater
NCT05943145
Quantitative Magnetic Resonance Imaging (MRI) Sub-Study of MS PATHS
Biogen
NCT04145284
Impact of Custom Assistive and Adaptive Technology in Rehabilitation
Madonna Rehabilitation Hospital
NCT03567239
Yoga: Effect on Attention in Aging & Multiple Sclerosis
National Center for Complementary and Integrative Health (NCCIH)
NCT00010998
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 41 |
| Phase 2 | 33 |
| Phase 3 | 24 |
| Phase 4 | 17 |
Top Sponsors
Named interventions
Most-linked intervention names on Multiple Sclerosis records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Multiple Sclerosis trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Multiple Sclerosis page
317 registered trials, 120 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 120 Multiple Sclerosis trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Biogen sponsors the most Multiple Sclerosis trials on record, review their full trial history before evaluating a specific study. See Biogen's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Multiple Sclerosis condition card totals 317 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.