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NCT04633759 · ClinicalTrials.gov registry record · NA

Low Load Resistance Training Using Blood Flow Restriction for People With Multiple Sclerosis

A NA study of Multiple Sclerosis, sponsored by University of Colorado, Denver.

Completed
Registry status
NA
Development phase
15
Enrollment target
1
Study location

NCT04633759: Completed NA study of Multiple Sclerosis, sponsored by University of Colorado, Denver.

NCT04633759 is a NA study of Multiple Sclerosis that has completed, run by University of Colorado, Denver. The registered enrollment target is 15 participants, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (97% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT04633759, a NA study of Multiple Sclerosis, has completed, sponsored by University of Colorado, Denver.

COMPLETED
Registry status
NA
Development phase
15 participants
Enrollment target
1
Study location

Study Summary

The Primary Aim of this research study is to determine the feasibility of 8 weeks of physical therapy strengthening exercises using blood flow restriction (BFR) in people with multiple sclerosis (MS) who have moderate-to-severe walking problems. BFR training involves placing a cuff on the leg being exercised in order to restrict blood flow. The cuff is attached to a specialized device that automatically detects the appropriate amount of pressure to place on the limb. Testing will occur before and after the 8-week treatment period.

Primary Outcome

Knee extension muscle strength measured by hand-held dynamometry on the more-involved side. The more-involved limb was determined at baseline assessment and defined as the limb with worse muscle strength.

Conditions Studied

Interventions

  • OTHER Blood Flow Restriction Exercise

Study Locations (1)

Colorado

  • University of Colorado - Aurora

Trial Details

FieldValue
Enrollment Target 15 participants
Start Date 2021-02-19
Est. Completion 2022-10-05
Phase NA
University of Colorado, Denver

1,283 total trials

What the finished NCT04633759 record still lists

NCT04633759 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 15 participants, a relatively small participant target, below the 585-participant average among 315 other Multiple Sclerosis trials with a reported enrollment target (97% lower).

The record links to 1 condition, with Multiple Sclerosis appearing as the primary indexed condition, and to 1 intervention - of which Blood Flow Restriction Exercise is the first listed.

NCT04633759 reports a single indexed study location in Colorado.

Frequently Asked Questions

What is clinical trial NCT04633759 about?

NCT04633759 is a clinical study titled "Low Load Resistance Training Using Blood Flow Restriction for People With Multiple Sclerosis". The Primary Aim of this research study is to determine the feasibility of 8 weeks of physical therapy strengthening exercises using blood flow restriction (BFR) in people with multiple sclerosis (MS) who have moderate-to-severe walking problems. BFR training involves placing a cuff on the leg being ...

What is the current status of trial NCT04633759?

This trial is currently completed. It is a NA study. The enrollment target is 15 participants. The study started on 2021-02-19. Estimated completion is 2022-10-05.

What conditions does trial NCT04633759 study?

This clinical trial studies the following conditions: Multiple Sclerosis.

What interventions are being tested in trial NCT04633759?

The interventions under investigation include: Blood Flow Restriction Exercise (OTHER).

Who is sponsoring clinical trial NCT04633759?

This trial is sponsored by University of Colorado, Denver, which has 1,283 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04633759 being conducted?

This trial has 1 study location across Colorado. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Multiple Sclerosis

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT04633759's enrollment target sits among peer trials

15 284th of 315 higher than 26 of 315 other Multiple Sclerosis trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Multiple Sclerosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT04633759, the US trial registry maintained by the National Library of Medicine. NCT04633759 (small enrollment · single site footprint · completed) retrieved and formatted by PlainTrial, see methodology.