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ClinicalTrials.gov 11 recruiting now later-stage tilt

Multiple Sclerosis (Relapsing Remitting): later-stage trial registry

11 of 30 indexed Multiple Sclerosis (Relapsing Remitting) trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #519 of 28,707 conditions by registered trial count.

30 US clinical trials · 11 currently recruiting · #519 of 28,707 conditions by registered trial count

Multiple Sclerosis (Relapsing Remitting): 30 US clinical trials tracked, 11 recruiting.

Multiple Sclerosis (Relapsing Remitting) is the subject of 30 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Shirley Ryan AbilityLab, running 4 of these trials.

Enrollment posture brief

Registry condition multiple-sclerosis-relapsing-remitting

OPEN 11 | RECR 37% | LATE 9 | EARLY 5 | RANK #519 | SPON 4

Nearest open-share peer: Bariatric Surgery Candidate (37% recruiting · 30 trials)

AML60%Acute Myeloid Leukemia40%Multiple Sclerosis (this)37%Anatomic Stage IA Breast Can26.7%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near Multiple Sclerosis (Relapsing Remitting)

Multiple Sclerosis (Relapsing Remitting) lists 11 open slots (37% of 30 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Multiple Sclerosis (Relapsing Remitting) on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Multiple Sclerosis (Relapsing Remitting) is recruiting below its size-band peers.

    11 of 30 indexed trials (36.7%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Multiple Sclerosis (Relapsing Remitting) trials is spread across many organizations.

    Shirley Ryan AbilityLab accounts for 4 of 30 trials (13.3%). 22 distinct sponsors appear on at least one study for this condition label.

  3. Typical Multiple Sclerosis (Relapsing Remitting) enrolment sits around 100 participants.

    Median target enrolment is 100 among the 30 trials that report a genuine target (sentinel values excluded). 15 of those (50%) plan for fewer than 100 participants.

  4. Multiple Sclerosis (Relapsing Remitting) research is mostly interventional.

    24 interventional and 6 observational studies make up this index (80% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 13Phase 22Phase 36Phase 43

Open and recent trials

30 total, page 1 of 1

RECRUITING 1,000 participants

MS-ResearchBiomarkerS

Cedars-Sinai Medical Center

NCT05204459

RECRUITING Phase 3 194 participants

Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis

Celgene

NCT06408259

RECRUITING NA 100 participants

Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation

The University of Texas at Dallas

NCT05958381

RECRUITING 80 participants

Investigating the Effect of Ocrelizumab in African Americans and Caucasians With Relapsing Multiple Sclerosis

Wayne State University

NCT04458688

RECRUITING Phase 1 74 participants

Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy

University of California, San Francisco

NCT05359653

RECRUITING NA 64 participants

Motor Learning of Fall Resistant Skills Through Slip and Trip Exposure in Multiple Sclerosis

Georgia State University

NCT06919900

RECRUITING 40 participants

Development of Camera Based Gait Quality Measure for Persons With Multiple Sclerosis

Shirley Ryan AbilityLab

NCT06516458

RECRUITING NA 22 participants

Effects of Acute Intermittent Hypoxia on Neuroplasticity in MS

Shirley Ryan AbilityLab

NCT06390930

RECRUITING NA 21 participants

Intermittent Hypoxia in Persons With Multiple Sclerosis

Shirley Ryan AbilityLab

NCT06276634

RECRUITING NA 14 participants

Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis

Cionic

NCT05964829

RECRUITING Phase 4 5 participants

Effects of Ocrelizumab Treatment on Immune Cells in Lymph Nodes in Multiple Sclerosis

University of California, San Francisco

NCT06495593

ACTIVE NOT RECRUITING 9,000 participants

A Post-Authorization, Long-term Study of Ozanimod Real-world Safety

Bristol-Myers Squibb

NCT05605782

ACTIVE NOT RECRUITING Phase 3 1,100 participants

Study to Evaluate the Efficacy, Safety and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis

Immunic

NCT05201638

ACTIVE NOT RECRUITING NA 900 participants

Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial

Johns Hopkins University

NCT03500328

ACTIVE NOT RECRUITING Phase 4 800 participants

Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for RRMS

The Cleveland Clinic

NCT03535298

ACTIVE NOT RECRUITING NA 162 participants

Efficacy of Diet on Quality of Life in Multiple Sclerosis

Terry L. Wahls

NCT05007483

ACTIVE NOT RECRUITING Phase 3 152 participants

A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis

Biogen

NCT03958877

ACTIVE NOT RECRUITING NA 40 participants

The Synergistic Effects of AIH and FES in Persons With MS

Shirley Ryan AbilityLab

NCT06413602

COMPLETED Phase 3 1,016 participants

A Study to Asses Efficacy, Safety and Tolerability of Monthly Long-acting IM Injection of GA Depot in Subjects With RMS

Mapi Pharma

NCT04121221

COMPLETED Phase 3 608 participants

A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)

Genentech

NCT02637856

COMPLETED Phase 4 271 participants

An Efficacy and Safety Comparison Study of Two Marketed Drugs in Patients With Relapsing-remitting MS

Bayer

NCT00206648

COMPLETED 160 participants

Observational Registry of Acthar Gel for Participants With Multiple Sclerosis Relapse

Mallinckrodt

NCT02633033

COMPLETED 155 participants

A Study of Multiple Sclerosis Routine Clinical Practice: Impact on Adherence and Clinical Outcomes of Ofatumumab Treated Patients

Novartis Pharmaceuticals

NCT06897657

COMPLETED Phase 1 105 participants

Intranasal Insulin for Improving Cognitive Function in Multiple Sclerosis

Johns Hopkins University

NCT02988401

COMPLETED Phase 2 63 participants

Extension of Prior Study Evaluating Safety and Tolerability of Two Doses of Betaseron® to Treat Relapsing-remitting Multiple Sclerosis

Bayer

NCT00235989

COMPLETED NA 57 participants

Pharmacokinetics of Vitamin D in Multiple Sclerosis and in Health

Johns Hopkins University

NCT01667796

COMPLETED Phase 2 50 participants

Assessment of Clemastine Fumarate as a Remyelinating Agent in Multiple Sclerosis

University of California, San Francisco

NCT02040298

COMPLETED NA 35 participants

Light Therapy as Treatment for Fatigue in Multiple Sclerosis

Massachusetts General Hospital

NCT03060759

COMPLETED Phase 1 20 participants

Safety of RG2077 in Patients With Multiple Sclerosis

National Institute of Allergy and Infectious Diseases (NIAID)

NCT00076934

COMPLETED Phase 3 8 participants

ACTH for Fatigue in Multiple Sclerosis Patients

Providence Health & Services

NCT02315872

Phase Distribution

PhaseTrial count
Phase 1 3
Phase 2 2
Phase 3 6
Phase 4 3

Top Sponsors

Named interventions

Most-linked intervention names on Multiple Sclerosis (Relapsing Remitting) records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Acute Intermittent Hypoxia Other
3 trials
Placebo Drug
3 trials
Ocrelizumab Drug
2 trials
Placebo Other
2 trials
Placebo (Sterile diluent) Drug
1 trials
Light Therapy box Device
1 trials
GA Depot Drug
1 trials
Betaferon/Betaseron Drug
1 trials

US sites by state

Facility locations filed on Multiple Sclerosis (Relapsing Remitting) trials. A trial with sites in several states counts in each.

California 12 trials
Illinois 9 trials
Florida 7 trials
Ohio 5 trials
Maryland 5 trials
Alabama 5 trials
Texas 4 trials
Georgia 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Multiple Sclerosis (Relapsing Remitting) page

30 registered trials, 11 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 11 Multiple Sclerosis (Relapsing Remitting) trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Shirley Ryan AbilityLab sponsors the most Multiple Sclerosis (Relapsing Remitting) trials on record, review their full trial history before evaluating a specific study. See Shirley Ryan AbilityLab's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Multiple Sclerosis (Relapsing Remitting) condition card totals 30 registered trials; most-linked intervention Acute Intermittent Hypoxia; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.