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Multiple Sclerosis (Relapsing Remitting) clinical trials
11 of 30 indexed Multiple Sclerosis (Relapsing Remitting) trials are currently recruiting.
30 US clinical trials · 11 currently recruiting
Multiple Sclerosis (Relapsing Remitting) is the subject of 30 registered US clinical trials on ClinicalTrials.gov, 11 of them currently open to new participants. 9 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Shirley Ryan AbilityLab, running 4 of these trials.
The research picture
Multiple Sclerosis (Relapsing Remitting) has 30 registered US clinical trials, 11 of them open to new participants right now, about 37% of the total.
- 11
- recruiting participants now
- 37%
- of trials open to enrollment
- 9
- in Phase 3–4 (later-stage)
- 4
- top sponsor: Shirley Ryan AbilityLab
Active & Recent Trials
30 total, page 1 of 1
MS-ResearchBiomarkerS
Cedars-Sinai Medical Center
NCT05204459
Study to Evaluate the Effectiveness and Safety of Ozanimod Compared to Fingolimod in Children and Adolescents With Relapsing Remitting Multiple Sclerosis
Celgene
NCT06408259
Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation
The University of Texas at Dallas
NCT05958381
Investigating the Effect of Ocrelizumab in African Americans and Caucasians With Relapsing Multiple Sclerosis
Wayne State University
NCT04458688
Assessing Changes in Multi-parametric MRI in MS Patients Taking Clemastine Fumarate as a Myelin Repair Therapy
University of California, San Francisco
NCT05359653
Motor Learning of Fall Resistant Skills Through Slip and Trip Exposure in Multiple Sclerosis
Georgia State University
NCT06919900
Development of Camera Based Gait Quality Measure for Persons With Multiple Sclerosis
Shirley Ryan AbilityLab
NCT06516458
Effects of Acute Intermittent Hypoxia on Neuroplasticity in MS
Shirley Ryan AbilityLab
NCT06390930
Intermittent Hypoxia in Persons With Multiple Sclerosis
Shirley Ryan AbilityLab
NCT06276634
Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis
Cionic
NCT05964829
Effects of Ocrelizumab Treatment on Immune Cells in Lymph Nodes in Multiple Sclerosis
University of California, San Francisco
NCT06495593
A Post-Authorization, Long-term Study of Ozanimod Real-world Safety
Bristol-Myers Squibb
NCT05605782
Study to Evaluate the Efficacy, Safety and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis
Immunic
NCT05201638
Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial
Johns Hopkins University
NCT03500328
Determining the Effectiveness of earLy Intensive Versus Escalation Approaches for RRMS
The Cleveland Clinic
NCT03535298
Efficacy of Diet on Quality of Life in Multiple Sclerosis
Terry L. Wahls
NCT05007483
A Study to Evaluate the Safety, Tolerability, and Efficacy of BIIB017 (Peginterferon Beta-1a) in Pediatric Participants for the Treatment of Relapsing-Remitting Multiple Sclerosis
Biogen
NCT03958877
The Synergistic Effects of AIH and FES in Persons With MS
Shirley Ryan AbilityLab
NCT06413602
A Study to Asses Efficacy, Safety and Tolerability of Monthly Long-acting IM Injection of GA Depot in Subjects With RMS
Mapi Pharma
NCT04121221
A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)
Genentech
NCT02637856
An Efficacy and Safety Comparison Study of Two Marketed Drugs in Patients With Relapsing-remitting MS
Bayer
NCT00206648
Observational Registry of Acthar Gel for Participants With Multiple Sclerosis Relapse
Mallinckrodt
NCT02633033
A Study of Multiple Sclerosis Routine Clinical Practice: Impact on Adherence and Clinical Outcomes of Ofatumumab Treated Patients
Novartis Pharmaceuticals
NCT06897657
Intranasal Insulin for Improving Cognitive Function in Multiple Sclerosis
Johns Hopkins University
NCT02988401
Extension of Prior Study Evaluating Safety and Tolerability of Two Doses of Betaseron® to Treat Relapsing-remitting Multiple Sclerosis
Bayer
NCT00235989
Pharmacokinetics of Vitamin D in Multiple Sclerosis and in Health
Johns Hopkins University
NCT01667796
Assessment of Clemastine Fumarate as a Remyelinating Agent in Multiple Sclerosis
University of California, San Francisco
NCT02040298
Light Therapy as Treatment for Fatigue in Multiple Sclerosis
Massachusetts General Hospital
NCT03060759
Safety of RG2077 in Patients With Multiple Sclerosis
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00076934
ACTH for Fatigue in Multiple Sclerosis Patients
Providence Health & Services
NCT02315872
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 3 |
| Phase 2 | 2 |
| Phase 3 | 6 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Multiple Sclerosis (Relapsing Remitting) Trial Landscape
30 indexed Multiple Sclerosis (Relapsing Remitting) studies · 11 recruiting (37%).
Phase mix: 9 late (III/IV) vs 5 early (I/II).
Top sponsor: Shirley Ryan AbilityLab (4 trials), 9 others listed. 30 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Multiple Sclerosis (Relapsing Remitting)?
PlainTrial tracks 30 US clinical trials for Multiple Sclerosis (Relapsing Remitting), of which 11 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Multiple Sclerosis (Relapsing Remitting)?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.