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NCT02040298 · ClinicalTrials.gov registry record · Phase 2

Assessment of Clemastine Fumarate as a Remyelinating Agent in Multiple Sclerosis

A Phase 2 study of Multiple Sclerosis (Relapsing Remitting), sponsored by University of California, San Francisco.

Completed
Registry status
Phase 2
Development phase
50
Enrollment target
1
Study location

NCT02040298 is a Phase 2 study of Multiple Sclerosis (Relapsing Remitting) that has completed, run by University of California, San Francisco. The registered enrollment target is 50 participants, below the 561-participant average among 29 other Multiple Sclerosis (Relapsing Remitting) trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02040298, a Phase 2 study of Multiple Sclerosis (Relapsing Remitting), has completed, sponsored by University of California, San Francisco.

COMPLETED
Registry status
Phase 2
Development phase
50 participants
Enrollment target
1
Study location

Study Summary

The main purpose of this study is to assess clemastine as a remyelinating agent in patients with relapsing forms of multiple sclerosis. The study will also evaluate the tolerability of clemastine, originally approved as first-generation antihistamine, in patients with multiple sclerosis. Study procedures will include assessments for evidence of remyelination in the anterior visual pathway and in the brain using electrophysiologic techniques and magnetic resonance imaging. The study will also assess the robustness and stability of this clinical effect in patients taking clemastine for up to 3 months. Patients in this study can remain on their standard disease modifying treatment during the course of the study. However, patients cannot participate in any other investigational new drug research study concurrently.

Interventions

  • DRUG Placebo
  • DRUG Clemastine

Study Locations (1)

California

  • UCSF Multiple Sclerosis Center - San Francisco

Trial Details

FieldValue
Enrollment Target 50 participants
Start Date 2014-01
Est. Completion 2016-04
Phase Phase 2

What the Registry Record Tells You About NCT02040298

The ClinicalTrials.gov registry entry for NCT02040298 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 50 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 561-participant average among 29 other Multiple Sclerosis (Relapsing Remitting) trials with a reported enrollment target (91% lower). The listed sponsor is University of California, San Francisco, which has 1,713 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Multiple Sclerosis (Relapsing Remitting) appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT02040298 reports 1 study location spanning 1 distinct geographic area - top geographies include California.

Frequently Asked Questions

What is clinical trial NCT02040298 about?

NCT02040298 is a clinical study titled "Assessment of Clemastine Fumarate as a Remyelinating Agent in Multiple Sclerosis". The main purpose of this study is to assess clemastine as a remyelinating agent in patients with relapsing forms of multiple sclerosis. The study will also evaluate the tolerability of clemastine, originally approved as first-generation antihistamine, in patients with multiple sclerosis. Study proce...

What is the current status of trial NCT02040298?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 50 participants. The study started on 2014-01. Estimated completion is 2016-04.

What conditions does trial NCT02040298 study?

This clinical trial studies the following conditions: Multiple Sclerosis (Relapsing Remitting).

What interventions are being tested in trial NCT02040298?

The interventions under investigation include: Placebo (DRUG), Clemastine (DRUG).

Who is sponsoring clinical trial NCT02040298?

This trial is sponsored by University of California, San Francisco, which has 1,713 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02040298 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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