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NCT02637856 · ClinicalTrials.gov registry record · Phase 3
A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)
A Phase 3 study of Multiple Sclerosis (Relapsing Remitting), sponsored by Genentech.
- Completed
- Registry status
- Phase 3
- Development phase
- 608
- Enrollment target
- 20
- Study locations
NCT02637856 is a Phase 3 study of Multiple Sclerosis (Relapsing Remitting) that has completed, run by Genentech. The registered enrollment target is 608 participants, above the 542-participant average among 29 other Multiple Sclerosis (Relapsing Remitting) trials with a reported enrollment target (12% higher). The trial reports 20 study locations across 6 states.
The verdict
NCT02637856, a Phase 3 study of Multiple Sclerosis (Relapsing Remitting), has completed, sponsored by Genentech.
- COMPLETED
- Registry status
- Phase 3
- Development phase
- 608 participants
- Enrollment target
- 20
- Study locations
Study Summary
This study will evaluate the efficacy and safety of ocrelizumab in participants with RRMS who have had a suboptimal response to an adequate course of DMT. Participants will receive ocrelizumab as an initial dose of two 300-milligrams (mg) intravenous (IV) infusions (600 mg total) separated by 14 days followed by one 600-mg IV infusion for a maximum of 4 doses (up to 96 weeks). Anticipated time on study treatment is 96 weeks.
Conditions Studied
Interventions
- DRUG Ocrelizumab
Study Locations (20)
California
- The Research Center of Southern California, LLC - Carlsbad
- Mercy Medical Group; MS Centre Nurse - Carmichael
- Fullerton Neurology and Headache Center - Fullerton
- Scripps Health - La Jolla
- UCSF- Multiple Sclerosis Centre; Department of Neurology - San Francisco
- Los Angeles Biomedical Research Institute at Harbor-UCLA Medical Center - Torrance
Colorado
- Mountain Neurological Research Center; Roaring Fork Neurologt, P.C. - Basalt
- IMMUNOe Research Centers - Centennial
- Colorado Neurological Institute - Englewood
- Advanced Neurology of Colorado, LLC - Fort Collins
Florida
- Neurology Associates PA - Maitland
- University of Miami Miller School of Medicine; Clinical Reseach Building - Miami
- Neurostudies Inc - Port Charlotte
- Infinity Clinical Research, LLC - Sunrise
Arizona
- Phoenix Neurological Associates Ltd - Phoenix
- Barrow Neurological Institute - Phoenix
- Territory Neurology and Research Institute - Tucson
Connecticut
- Associated Neurologists of Southern CT PC - Fairfield
- KI Health Partners, LLC; New England Institute for Clinical Research - Stamford
Alabama
- North Central Neurology Associates - Cullman
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 608 participants |
| Start Date | 2016-02-11 |
| Est. Completion | 2019-05-03 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT02637856
The ClinicalTrials.gov registry entry for NCT02637856 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 608 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 542-participant average among 29 other Multiple Sclerosis (Relapsing Remitting) trials with a reported enrollment target (12% higher). The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Multiple Sclerosis (Relapsing Remitting) appearing as the primary indexed condition, and to 1 intervention - of which Ocrelizumab is the first listed.
NCT02637856 reports 20 study locations spanning 6 distinct geographic areas - top geographies include California, Colorado, Florida.
Frequently Asked Questions
What is clinical trial NCT02637856 about?
NCT02637856 is a clinical study titled "A Study of Ocrelizumab in Participants With Relapsing Remitting Multiple Sclerosis (RRMS) Who Have Had a Suboptimal Response to an Adequate Course of Disease-Modifying Treatment (DMT)". This study will evaluate the efficacy and safety of ocrelizumab in participants with RRMS who have had a suboptimal response to an adequate course of DMT. Participants will receive ocrelizumab as an initial dose of two 300-milligrams (mg) intravenous (IV) infusions (600 mg total) separated by 14 day...
What is the current status of trial NCT02637856?
This trial is currently completed. It is a Phase 3 study. The enrollment target is 608 participants. The study started on 2016-02-11. Estimated completion is 2019-05-03.
What conditions does trial NCT02637856 study?
This clinical trial studies the following conditions: Multiple Sclerosis (Relapsing Remitting).
What interventions are being tested in trial NCT02637856?
The interventions under investigation include: Ocrelizumab (DRUG).
Who is sponsoring clinical trial NCT02637856?
This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02637856 being conducted?
This trial has 20 study locations across Alabama, Arizona, California, Colorado, Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
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