Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT05958381 · ClinicalTrials.gov registry record · NA
Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation
A NA study of Multiple Sclerosis (Relapsing Remitting), sponsored by The University of Texas at Dallas.
- Recruiting
- Registry status
- NA
- Development phase
- 100
- Enrollment target
- 1
- Study location
NCT05958381: Recruiting NA study of Multiple Sclerosis (Relapsing Remitting), sponsored by The University of Texas at Dallas.
NCT05958381 is a NA study of Multiple Sclerosis (Relapsing Remitting) that is actively recruiting participants, run by The University of Texas at Dallas. The registered enrollment target is 100 participants, below the 559-participant average among 29 other Multiple Sclerosis (Relapsing Remitting) trials with a reported enrollment target (82% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05958381, a NA study of Multiple Sclerosis (Relapsing Remitting), is actively recruiting participants, sponsored by The University of Texas at Dallas.
- RECRUITING
- Registry status
- NA
- Development phase
- 100 participants
- Enrollment target
- 1
- Study location
Study Summary
The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., presupplementary motor area) thought to aid in memory will improve verbal retrieval in multiple sclerosis patients. The primary outcome measures are neuropsychological assessments of verbal retrieval, and the secondary measures are neuropsychological assessments of other cognitive abilities and electroencephalography (EEG) measures. Additionally, the study will examine the degree to which baseline assessments of cognition and concussion history predict responses to treatment over time, both on assessments administered within the intervention period and at follow-up.
Primary Outcome
Evaluation of treatment group differences in change on Category Fluency from baseline to 1-week post-treatment. Metric: Number of Correct Items Generated
Conditions Studied
Interventions
- DEVICE Sham transcranial direct current stimulation
- DEVICE Transcranial Direct Current Stimulation
Study Locations (1)
Texas
- The University of Texas at Dallas - Richardson
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 100 participants |
| Start Date | 2023-10-18 |
| Est. Completion | 2027-06-30 |
| Phase | NA |
What NCT05958381 shows while recruiting
NCT05958381 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 559-participant average among 29 other Multiple Sclerosis (Relapsing Remitting) trials with a reported enrollment target (82% lower).
The record links to 1 condition, with Multiple Sclerosis (Relapsing Remitting) appearing as the primary indexed condition, and to 2 interventions - of which Sham transcranial direct current stimulation is the first listed.
NCT05958381 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT05958381 about?
NCT05958381 is a clinical study titled "Treatment of Cognitive Deficits in Multiple Sclerosis With High-Definition Transcranial Direct Current Stimulation". The purpose of the study is to test whether low level electric stimulation, called transcranial Direct Current Stimulation (tDCS), on the part of the brain (i.e., presupplementary motor area) thought to aid in memory will improve verbal retrieval in multiple sclerosis patients. The primary outcome m...
What is the current status of trial NCT05958381?
This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2023-10-18. Estimated completion is 2027-06-30.
What conditions does trial NCT05958381 study?
This clinical trial studies the following conditions: Multiple Sclerosis (Relapsing Remitting).
What interventions are being tested in trial NCT05958381?
The interventions under investigation include: Sham transcranial direct current stimulation (DEVICE), Transcranial Direct Current Stimulation (DEVICE).
Who is sponsoring clinical trial NCT05958381?
This trial is sponsored by The University of Texas at Dallas, which has 50 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05958381 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Multiple Sclerosis (Relapsing Remitting)
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05958381's enrollment target sits among peer trials
100 15th of 29 higher than 15 of 29 other Multiple Sclerosis (Relapsing Remitting) trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Multiple Sclerosis (Relapsing Remitting) trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Motor Learning of Fall Resistant Skills Through Slip and Trip Exposure in Multiple Sclerosis
RECRUITING · NA
-
Intermittent Hypoxia in Persons With Multiple Sclerosis
RECRUITING · NA
-
Effects of Acute Intermittent Hypoxia on Neuroplasticity in MS
RECRUITING · NA
-
Impact of the Cionic Neural Sleeve on Mobility in Multiple Sclerosis
RECRUITING · NA
-
The Synergistic Effects of AIH and FES in Persons With MS
ACTIVE NOT RECRUITING · NA
-
Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial
ACTIVE NOT RECRUITING · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT01048281 · 100 participants
Clinical & Pathological Studies of Upper Gastrointestinal Carcinoma
- NCT01161199 · 100 participants
The Use of Leukapheresis to Support HIV Pathogenesis Studies
- NCT01327690 · 100 participants · Early Phase 1
Mental Health in Veterans and Families After Group Therapies
- NCT01730781 · 100 participants
Imaging Cannabinoid Receptors Using Positron Emission Tomography (PET) Scanning
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI