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NCT02988401 · ClinicalTrials.gov registry record · Phase 1

Intranasal Insulin for Improving Cognitive Function in Multiple Sclerosis

A Phase 1 study of Multiple Sclerosis (Relapsing Remitting) and Multiple Sclerosis, Secondary Progressive, sponsored by Johns Hopkins University.

Completed
Registry status
Phase 1
Development phase
105
Enrollment target
1
Study location

NCT02988401 is a Phase 1 study of Multiple Sclerosis (Relapsing Remitting) and Multiple Sclerosis, Secondary Progressive that has completed, run by Johns Hopkins University. The registered enrollment target is 105 participants, below the 559-participant average among 29 other Multiple Sclerosis (Relapsing Remitting) trials with a reported enrollment target (81% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02988401, a Phase 1 study of Multiple Sclerosis (Relapsing Remitting) and Multiple Sclerosis, Secondary Progressive, has completed, sponsored by Johns Hopkins University.

COMPLETED
Registry status
Phase 1
Development phase
105 participants
Enrollment target
1
Study location

Study Summary

This study will evaluate if giving insulin that is administered in the nostrils (intranasal) is safe and tolerable for people with multiple sclerosis (MS). It is also being done to evaluate if intranasal insulin improves cognitive function in people with MS and to evaluate how it might be working.

Interventions

  • DRUG Insulin
  • DRUG Placebo (Sterile diluent)

Study Locations (1)

Maryland

  • Johns Hopkins University School of Medicine - Baltimore

Trial Details

FieldValue
Enrollment Target 105 participants
Start Date 2017-12-01
Est. Completion 2021-12-17
Phase Phase 1

Sponsor

Johns Hopkins University

1,448 total trials

What the Registry Record Tells You About NCT02988401

The ClinicalTrials.gov registry entry for NCT02988401 describes a study currently listed as completed, categorized as Phase 1. The registered enrollment target is 105 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 559-participant average among 29 other Multiple Sclerosis (Relapsing Remitting) trials with a reported enrollment target (81% lower). The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.

The record links to 3 conditions, with Multiple Sclerosis (Relapsing Remitting) appearing as the primary indexed condition, and to 2 interventions - of which Insulin is the first listed.

NCT02988401 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.

Frequently Asked Questions

What is clinical trial NCT02988401 about?

NCT02988401 is a clinical study titled "Intranasal Insulin for Improving Cognitive Function in Multiple Sclerosis". This study will evaluate if giving insulin that is administered in the nostrils (intranasal) is safe and tolerable for people with multiple sclerosis (MS). It is also being done to evaluate if intranasal insulin improves cognitive function in people with MS and to evaluate how it might be working.

What is the current status of trial NCT02988401?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 105 participants. The study started on 2017-12-01. Estimated completion is 2021-12-17.

What conditions does trial NCT02988401 study?

This clinical trial studies the following conditions: Multiple Sclerosis (Relapsing Remitting), Multiple Sclerosis, Secondary Progressive, Multiple Sclerosis, Primary Progressive.

What interventions are being tested in trial NCT02988401?

The interventions under investigation include: Insulin (DRUG), Placebo (Sterile diluent) (DRUG).

Who is sponsoring clinical trial NCT02988401?

This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02988401 being conducted?

This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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