Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
A Mobile Gaming App to Improve Adherence to PrEP
NCT05762705 · View on ClinicalTrials.gov ↗
Study Summary
In this study, the investigators will test the mobile game, Viral Combat, for efficacy and acceptability among diverse participants, ages 15-34 years, receiving PrEP care in clinical settings in New England and Mississippi. Formative evaluation interviews will be conducted with stakeholders (healthcare workers, clinic administrators, and patients taking PrEP) to inform intervention delivery. Data from the formative interviews will also be used to make necessary adaptations to the game and assess acceptability for diverse populations and clinics. Viral Combat will then be further tested with 200 participants ages 15-34 years, receiving PrEP care at clinical sites in the South (n=100 Jackson, MS) and New England (n=100, Providence, RI; Boston, MA) in a multisite Hybrid Type 1 effectiveness-implementation randomized controlled trial (RCT). This trial will test the efficacy of the intervention compared to a control condition (a non-PrEP related game) on biological and behavioral measures. At the end of the trial, a summative evaluation of the implementation context using the i-PARIHS framework will occur. These interviews with study participants and clinic staff will inform future implementation and dissemination of Viral Combat.
Conditions Studied
Interventions
- BEHAVIORAL Multilevel Gaming Adherence Intervention
- BEHAVIORAL Treatment as Usual +
Study Locations (3)
Massachusetts
- Boston Medical Center — Boston
Mississippi
- University of Mississippi Medical Center — Jackson
Rhode Island
- Lifespan (The Miriam Hospital and Rhode Island Hospital) — Providence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2024-06-21 |
| Est. Completion | 2027-03-03 |
| Phase | NA |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT05762705
The ClinicalTrials.gov registry entry for NCT05762705 describes a study currently listed as recruiting. It is categorized as NA, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 200 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Rhode Island Hospital, which has 110 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with HIV/AIDS appearing as the primary indexed condition, and to 2 interventions — of which Multilevel Gaming Adherence Intervention is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT05762705 reports 3 study locations spanning 3 distinct geographic areas — top geographies include Massachusetts, Mississippi, Rhode Island. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT05762705 about?
NCT05762705 is a clinical study titled "A Mobile Gaming App to Improve Adherence to PrEP". In this study, the investigators will test the mobile game, Viral Combat, for efficacy and acceptability among diverse participants, ages 15-34 years, receiving PrEP care in clinical settings in New England and Mississippi. Formative evaluation interviews will be conducted with stakeholders (healthc...
What is the current status of trial NCT05762705?
This trial is currently recruiting. It is a NA study. The enrollment target is 200 participants. The study started on 2024-06-21. Estimated completion is 2027-03-03.
What conditions does trial NCT05762705 study?
This clinical trial studies the following conditions: HIV/AIDS, Medication Adherence. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT05762705?
The interventions under investigation include: Multilevel Gaming Adherence Intervention (BEHAVIORAL), Treatment as Usual + (BEHAVIORAL). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT05762705?
This trial is sponsored by Rhode Island Hospital, which has 110 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT05762705 being conducted?
This trial has 3 study locations across Massachusetts, Mississippi, Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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