Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04302896 · ClinicalTrials.gov registry record · Early Phase 1

Development of a Urine-Based Point-of-Care Test for Adherence to Antiretroviral Drugs

A Early Phase 1 study of HIV and Medication Adherence, sponsored by Rhonda Brand.

Completed
Registry status
Early Phase 1
Development phase
30
Enrollment target
1
Study location

NCT04302896 is a Early Phase 1 study of HIV and Medication Adherence that has completed, run by Rhonda Brand. The registered enrollment target is 30 participants, below the 440-participant average among 303 other HIV trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04302896, a Early Phase 1 study of HIV and Medication Adherence, has completed, sponsored by Rhonda Brand.

COMPLETED
Registry status
Early Phase 1
Development phase
30 participants
Enrollment target
1
Study location

Study Summary

This is a single-center, open label study to identify adherence levels of commonly prescribed FDA-approved antiretroviral agents by tracking the decline of drug concentrations in plasma, urine and saliva following abrupt drug cessation in HIV-negative adults. Results from this study may provide support for development of a point of care urine testing device to monitor drug adherence.

Conditions Studied

Interventions

  • DRUG dolutegravir oral tablet 50mg
  • DRUG emtricitabine/tenofovir alafenamide oral tablet 200mg/25mg
  • DRUG tenofovir disoproxil fumarate oral tablet 300mg
  • DRUG lamivudine oral tablet 300mg

Study Locations (1)

Pennsylvania

  • HIV/AIDS Clinical Research Unit / University of Pittsburgh - Pittsburgh

Trial Details

FieldValue
Enrollment Target 30 participants
Start Date 2020-08-31
Est. Completion 2021-09-30
Phase Early Phase 1

Sponsor

Rhonda Brand

2 total trials

What the Registry Record Tells You About NCT04302896

The ClinicalTrials.gov registry entry for NCT04302896 describes a study currently listed as completed, categorized as Early Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 440-participant average among 303 other HIV trials with a reported enrollment target (93% lower). The listed sponsor is Rhonda Brand, which has 2 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with HIV appearing as the primary indexed condition, and to 4 interventions - of which dolutegravir oral tablet 50mg is the first listed.

NCT04302896 reports 1 study location spanning 1 distinct geographic area - top geographies include Pennsylvania.

Frequently Asked Questions

What is clinical trial NCT04302896 about?

NCT04302896 is a clinical study titled "Development of a Urine-Based Point-of-Care Test for Adherence to Antiretroviral Drugs". This is a single-center, open label study to identify adherence levels of commonly prescribed FDA-approved antiretroviral agents by tracking the decline of drug concentrations in plasma, urine and saliva following abrupt drug cessation in HIV-negative adults. Results from this study may provide supp...

What is the current status of trial NCT04302896?

This trial is currently completed. It is a Early Phase 1 study. The enrollment target is 30 participants. The study started on 2020-08-31. Estimated completion is 2021-09-30.

What conditions does trial NCT04302896 study?

This clinical trial studies the following conditions: HIV, Medication Adherence.

What interventions are being tested in trial NCT04302896?

The interventions under investigation include: dolutegravir oral tablet 50mg (DRUG), emtricitabine/tenofovir alafenamide oral tablet 200mg/25mg (DRUG), tenofovir disoproxil fumarate oral tablet 300mg (DRUG), lamivudine oral tablet 300mg (DRUG).

Who is sponsoring clinical trial NCT04302896?

This trial is sponsored by Rhonda Brand, which has 2 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04302896 being conducted?

This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for HIV

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.