Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Low Back Pain clinical trials
31 of 123 indexed Low Back Pain trials are currently recruiting.
123 US clinical trials · 31 currently recruiting
Low Back Pain is the subject of 123 registered US clinical trials on ClinicalTrials.gov, 31 of them currently open to new participants. 20 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is University of Utah, running 8 of these trials.
The research picture
Low Back Pain has 123 registered US clinical trials, 31 of them open to new participants right now, about 25% of the total.
- 31
- recruiting participants now
- 25%
- of trials open to enrollment
- 20
- in Phase 3–4 (later-stage)
- 8
- top sponsor: University of Utah
Active & Recent Trials
123 total, page 3 of 3
A Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves for theTreatment of Lumbar Facet Syndrome
Northwestern University
NCT02478437
Regional Manual Therapy and Motor Control Exercise for Chronic Low Back Pain
University of Texas Southwestern Medical Center
NCT02170753
Translation of Robotic Apparel for Alleviating Low Back Pain
Boston University Charles River Campus
NCT05736393
D-cycloserine in the Management of Chronic Low Back Pain
Thomas J. Schnitzer
NCT00125528
Effects of Spinal Stabilization Exercises on Dynamic Balance and Functional Performance in Adults With Low Back Pain
Texas Woman's University
NCT03597191
Care Outcomes for Chiropractic Outpatient Veterans
Palmer College of Chiropractic
NCT03254719
Brain Imaging of Lidoderm for Chronic Back Pain
Northwestern University
NCT01515540
Multiplanar Lumbopelvic Control in Patients With Low Back Pain
Regis University
NCT02089321
Battlefield Acupuncture for the Treatment of Low Back Pain in the Emergency Department
Icahn School of Medicine at Mount Sinai
NCT02399969
Manual Unloading of the Lumbar Spine: Can it Predict Responders to Mechanical Traction?
UConn Health
NCT02026076
Cryoneurolysis for Facet Mediated Chronic Low Back Pain
Medical Pain Management Services, P
NCT06016127
Soleus H-Reflex in Different Sitting Postures
Texas Woman's University
NCT01744899
Trial of Scrambler Therapy or Sham Treatment for Low Back Pain
Virginia Commonwealth University
NCT01896687
Innovative Imaging of Cerebrum and Muscle (iCAM) Repeatability Study
Ohio University
NCT03548168
Intraarticular Lumbar Joint Corticosteroid Injection(s) as a Treatment of Chronic Low Back Pain in a Selected Population
University of Florida
NCT01382771
Soft Tissue Mobilization for Lumbopelvic Pain in the Third Trimester of Pregnancy
Texas Tech University Health Sciences Center
NCT03433404
Hip-spine Intervention for Older Adults With Chronic Low Back Pain
University of Delaware
NCT03031158
Misoprostol for Spinal Stenosis
Dallas VA Medical Center
NCT04611464
Feasibility of Using Functional Progression to Guide the Treatment of Adolescent Low Back Pain
Nationwide Children's Hospital
NCT02861456
measurINg forceS durInG cHiropractic Treatment
Palmer College of Chiropractic
NCT02409797
Veteran Ear Acupuncture Pilot Project
Chillicothe VA Medical Center
NCT04208659
FDG PET/MRI Evaluation of Facet Joint Pain
Mayo Clinic
NCT02921490
PRoGReSS-PS: Patient Response to GRraded Sensory Stimulation: A Pilot Study
Palmer College of Chiropractic
NCT01842737
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 7 |
| Phase 2 | 5 |
| Phase 3 | 12 |
| Phase 4 | 8 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Low Back Pain Trial Landscape
123 indexed Low Back Pain studies · 31 recruiting (25%).
Phase mix: 20 late (III/IV) vs 12 early (I/II).
Top sponsor: University of Utah (8 trials), 9 others listed. 23 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Low Back Pain?
PlainTrial tracks 123 US clinical trials for Low Back Pain, of which 31 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Low Back Pain?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.