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ClinicalTrials.gov 31 recruiting now later-stage tilt #97 of 28,707 conditions

Low Back Pain: later-stage trial registry

31 of 123 indexed Low Back Pain trials are currently recruiting, with more weight in Phase 3-4.

Corpus placement: #97 of 28,707 conditions by registered trial count.

123 US clinical trials · 31 currently recruiting · #97 of 28,707 conditions by registered trial count

Low Back Pain: 123 US clinical trials tracked, 31 recruiting.

Low Back Pain is the subject of 123 registered US clinical trials on ClinicalTrials.gov, 31 of them currently open to new participants. 20 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is University of Utah, running 8 of these trials.

Enrollment posture brief

Registry condition low-back-pain

OPEN 31 | RECR 25% | LATE 20 | EARLY 12 | RANK #97 | SPON 8

Nearest open-share peer: Overweight (25% recruiting · 198 trials)

Advanced Cancer36.6%Ulcerative Colitis36.6%Insulin Resistance26.2%Low Back Pain (this)25%Smoking21.8%
Open-enrollment share among volume-matched conditions near Low Back Pain

Low Back Pain lists 31 open slots (25% of 123 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Low Back Pain on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Low Back Pain is recruiting below its size-band peers.

    31 of 123 indexed trials (25.2%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Low Back Pain trials is spread across many organizations.

    University of Utah accounts for 8 of 123 trials (6.5%). 80 distinct sponsors appear on at least one study for this condition label.

  3. Typical Low Back Pain enrolment sits around 97 participants.

    Median target enrolment is 97 among the 123 trials that report a genuine target (sentinel values excluded). 63 of those (51.2%) plan for fewer than 100 participants.

  4. Low Back Pain research is mostly interventional.

    108 interventional and 15 observational studies make up this index (87.8% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 25Phase 312Phase 48

Open and recent trials

123 total, page 3 of 3

COMPLETED Phase 3 48 participants

A Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves for theTreatment of Lumbar Facet Syndrome

Northwestern University

NCT02478437

COMPLETED NA 46 participants

Regional Manual Therapy and Motor Control Exercise for Chronic Low Back Pain

University of Texas Southwestern Medical Center

NCT02170753

COMPLETED NA 44 participants

Translation of Robotic Apparel for Alleviating Low Back Pain

Boston University Charles River Campus

NCT05736393

COMPLETED Phase 2 41 participants

D-cycloserine in the Management of Chronic Low Back Pain

Thomas J. Schnitzer

NCT00125528

COMPLETED NA 40 participants

Effects of Spinal Stabilization Exercises on Dynamic Balance and Functional Performance in Adults With Low Back Pain

Texas Woman's University

NCT03597191

COMPLETED NA 40 participants

Care Outcomes for Chiropractic Outpatient Veterans

Palmer College of Chiropractic

NCT03254719

COMPLETED Phase 4 38 participants

Brain Imaging of Lidoderm for Chronic Back Pain

Northwestern University

NCT01515540

COMPLETED 38 participants

Multiplanar Lumbopelvic Control in Patients With Low Back Pain

Regis University

NCT02089321

COMPLETED Phase 1 30 participants

Battlefield Acupuncture for the Treatment of Low Back Pain in the Emergency Department

Icahn School of Medicine at Mount Sinai

NCT02399969

COMPLETED NA 30 participants

Manual Unloading of the Lumbar Spine: Can it Predict Responders to Mechanical Traction?

UConn Health

NCT02026076

COMPLETED NA 30 participants

Cryoneurolysis for Facet Mediated Chronic Low Back Pain

Medical Pain Management Services, P

NCT06016127

COMPLETED 30 participants

Soleus H-Reflex in Different Sitting Postures

Texas Woman's University

NCT01744899

COMPLETED NA 30 participants

Trial of Scrambler Therapy or Sham Treatment for Low Back Pain

Virginia Commonwealth University

NCT01896687

COMPLETED 28 participants

Innovative Imaging of Cerebrum and Muscle (iCAM) Repeatability Study

Ohio University

NCT03548168

COMPLETED Early Phase 1 28 participants

Intraarticular Lumbar Joint Corticosteroid Injection(s) as a Treatment of Chronic Low Back Pain in a Selected Population

University of Florida

NCT01382771

COMPLETED NA 26 participants

Soft Tissue Mobilization for Lumbopelvic Pain in the Third Trimester of Pregnancy

Texas Tech University Health Sciences Center

NCT03433404

COMPLETED NA 24 participants

Hip-spine Intervention for Older Adults With Chronic Low Back Pain

University of Delaware

NCT03031158

COMPLETED 23 participants

Misoprostol for Spinal Stenosis

Dallas VA Medical Center

NCT04611464

COMPLETED NA 16 participants

Feasibility of Using Functional Progression to Guide the Treatment of Adolescent Low Back Pain

Nationwide Children's Hospital

NCT02861456

COMPLETED NA 12 participants

measurINg forceS durInG cHiropractic Treatment

Palmer College of Chiropractic

NCT02409797

COMPLETED NA 12 participants

Veteran Ear Acupuncture Pilot Project

Chillicothe VA Medical Center

NCT04208659

COMPLETED NA 10 participants

FDG PET/MRI Evaluation of Facet Joint Pain

Mayo Clinic

NCT02921490

COMPLETED NA 8 participants

PRoGReSS-PS: Patient Response to GRraded Sensory Stimulation: A Pilot Study

Palmer College of Chiropractic

NCT01842737

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Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 5
Phase 3 12
Phase 4 8

Named interventions

Most-linked intervention names on Low Back Pain records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
6 trials
Oxycodone HCl controlled-release Drug
2 trials
Oxycodone/Naloxone controlled-release Drug
2 trials
Back Exosuit Device
2 trials
SPRINT Peripheral Nerve Stimulation (PNS) System Device
2 trials
Computerized Chemosensory-Based Orbitofrontal Cortex Training (CBOT) Combination
2 trials
Telehealth Physical Therapy Behavioral
2 trials
Ibuprofen 400 mg Drug
2 trials

US sites by state

Facility locations filed on Low Back Pain trials. A trial with sites in several states counts in each.

Texas 21 trials
California 19 trials
Ohio 12 trials
Florida 12 trials
Utah 10 trials
New York 10 trials
Illinois 10 trials
Arizona 10 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Low Back Pain page

123 registered trials, 31 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Low Back Pain condition card totals 123 registered trials; most-linked intervention Placebo; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.