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NCT02478437 · ClinicalTrials.gov registry record · Phase 3

A Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves for theTreatment of Lumbar Facet Syndrome

A Phase 3 study of Low Back Pain, sponsored by Northwestern University.

Completed
Registry status
Phase 3
Development phase
48
Enrollment target
1
Study location

NCT02478437 is a Phase 3 study of Low Back Pain that has completed, run by Northwestern University. The registered enrollment target is 48 participants, below the 503-participant average among 122 other Low Back Pain trials with a reported enrollment target (90% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02478437, a Phase 3 study of Low Back Pain, has completed, sponsored by Northwestern University.

COMPLETED
Registry status
Phase 3
Development phase
48 participants
Enrollment target
1
Study location

Study Summary

This study is being done to determine whether cooled radiofrequency ablation (CRFA) on the medial branch nerves of the lumbar facet joint is effective for the treatment of low back pain. CRFA blocks the nerves that carry pain signals from joints in the lower back such that the brain does not receive the message that the low back is in pain. This technique is commonly performed by burning these nerves rather freezing them, but it is suspected that freezing them results in better pain relief. The CRFA blocks has been shown to effectively treat sacroiliac joint pain (a joint in the pelvis), which is another reason that it is suspected that CRFA will be effective when treating pain related to facet joints in the low back. We are performing this study in order to determine if that is the case.

Conditions Studied

Interventions

  • PROCEDURE Conventional radiofrequency ablation (RFA)
  • PROCEDURE Cooled Radiofrequency Ablation (CRFA)

Study Locations (1)

Illinois

  • Anesthesiology Pain Managment Center - Chicago

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2015-06
Est. Completion 2018-08
Phase Phase 3

Sponsor

Northwestern University

1,209 total trials

What the Registry Record Tells You About NCT02478437

The ClinicalTrials.gov registry entry for NCT02478437 describes a study currently listed as completed, categorized as Phase 3. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 503-participant average among 122 other Low Back Pain trials with a reported enrollment target (90% lower). The listed sponsor is Northwestern University, which has 1,209 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Low Back Pain appearing as the primary indexed condition, and to 2 interventions - of which Conventional radiofrequency ablation (RFA) is the first listed.

NCT02478437 reports 1 study location spanning 1 distinct geographic area - top geographies include Illinois.

Frequently Asked Questions

What is clinical trial NCT02478437 about?

NCT02478437 is a clinical study titled "A Trial of Cooled Radiofrequency Ablation of Medial Branch Nerves for theTreatment of Lumbar Facet Syndrome". This study is being done to determine whether cooled radiofrequency ablation (CRFA) on the medial branch nerves of the lumbar facet joint is effective for the treatment of low back pain. CRFA blocks the nerves that carry pain signals from joints in the lower back such that the brain does not receive...

What is the current status of trial NCT02478437?

This trial is currently completed. It is a Phase 3 study. The enrollment target is 48 participants. The study started on 2015-06. Estimated completion is 2018-08.

What conditions does trial NCT02478437 study?

This clinical trial studies the following conditions: Low Back Pain.

What interventions are being tested in trial NCT02478437?

The interventions under investigation include: Conventional radiofrequency ablation (RFA) (PROCEDURE), Cooled Radiofrequency Ablation (CRFA) (PROCEDURE).

Who is sponsoring clinical trial NCT02478437?

This trial is sponsored by Northwestern University, which has 1,209 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02478437 being conducted?

This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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