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NCT02921490 · ClinicalTrials.gov registry record · NA

FDG PET/MRI Evaluation of Facet Joint Pain

A NA study of Low Back Pain, sponsored by Mayo Clinic.

Completed
Registry status
NA
Development phase
10
Enrollment target
1
Study location

NCT02921490 is a NA study of Low Back Pain that has completed, run by Mayo Clinic. The registered enrollment target is 10 participants, below the 504-participant average among 122 other Low Back Pain trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT02921490, a NA study of Low Back Pain, has completed, sponsored by Mayo Clinic.

COMPLETED
Registry status
NA
Development phase
10 participants
Enrollment target
1
Study location

Study Summary

Chronic pain incurs over half a trillion dollars in lost productivity (healthcare, lost wages, etc) annually. The most common source is low back pain (LBP), often from facet joints. The clinical evaluation of facet joints is challenging and anatomic imaging findings of facet joint; degenerative change; correlate poorly with pain. Therefore, it is difficult to select appropriate candidate patients/facet joints to treat. Misguided percutaneous treatment can cost thousands of dollars per session and delay diagnoses. Very limited retrospective information suggests that high grade peri-facet MRI signal change correlates to the side of LBP. However, this has not fully characterized the imaging findings and has not correlated to expert clinical exam/percutaneous response, precluding robust and meaningful clinical impact. Minimal retrospective data concludes inflammatory changes can be identified on FDG-PET exams, but the evidence of correlation to patient pain is lacking. Limited DWI exists for inflammatory spondyloarthropathies and myopathies, but is also lacking. This is an exploratory study investigating the utility of FDG PET activity and MRI signal change around facet joints in the clinical management of low back pain. This study will help determine if such imaging biomarkers could change clinical management. Additionally, this will provide data that will be vital to planning a larger prospective study evaluating the ability of imaging biomarkers to predict response to comparison medial branch blocks and RF ablation for treatment of facet joint pain.

Conditions Studied

Interventions

  • DEVICE FDG PET/MR examination.

Study Locations (1)

Minnesota

  • Mayo Clinic in Rochester - Rochester

Trial Details

FieldValue
Enrollment Target 10 participants
Start Date 2016-09
Est. Completion 2019-10
Phase NA

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT02921490

The ClinicalTrials.gov registry entry for NCT02921490 describes a study currently listed as completed, categorized as NA. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 504-participant average among 122 other Low Back Pain trials with a reported enrollment target (98% lower). The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Low Back Pain appearing as the primary indexed condition, and to 1 intervention - of which FDG PET/MR examination. is the first listed.

NCT02921490 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.

Frequently Asked Questions

What is clinical trial NCT02921490 about?

NCT02921490 is a clinical study titled "FDG PET/MRI Evaluation of Facet Joint Pain". Chronic pain incurs over half a trillion dollars in lost productivity (healthcare, lost wages, etc) annually. The most common source is low back pain (LBP), often from facet joints. The clinical evaluation of facet joints is challenging and anatomic imaging findings of facet joint; degenerative chan...

What is the current status of trial NCT02921490?

This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2016-09. Estimated completion is 2019-10.

What conditions does trial NCT02921490 study?

This clinical trial studies the following conditions: Low Back Pain.

What interventions are being tested in trial NCT02921490?

The interventions under investigation include: FDG PET/MR examination. (DEVICE).

Who is sponsoring clinical trial NCT02921490?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT02921490 being conducted?

This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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