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NCT02921490 · ClinicalTrials.gov registry record · NA
FDG PET/MRI Evaluation of Facet Joint Pain
A NA study of Low Back Pain, sponsored by Mayo Clinic.
- Completed
- Registry status
- NA
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT02921490: Completed NA study of Low Back Pain, sponsored by Mayo Clinic.
NCT02921490 is a NA study of Low Back Pain that has completed, run by Mayo Clinic. The registered enrollment target is 10 participants, below the 504-participant average among 122 other Low Back Pain trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT02921490, a NA study of Low Back Pain, has completed, sponsored by Mayo Clinic.
- COMPLETED
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
Chronic pain incurs over half a trillion dollars in lost productivity (healthcare, lost wages, etc) annually. The most common source is low back pain (LBP), often from facet joints. The clinical evaluation of facet joints is challenging and anatomic imaging findings of facet joint; degenerative change; correlate poorly with pain. Therefore, it is difficult to select appropriate candidate patients/facet joints to treat. Misguided percutaneous treatment can cost thousands of dollars per session and delay diagnoses. Very limited retrospective information suggests that high grade peri-facet MRI signal change correlates to the side of LBP. However, this has not fully characterized the imaging findings and has not correlated to expert clinical exam/percutaneous response, precluding robust and meaningful clinical impact. Minimal retrospective data concludes inflammatory changes can be identified on FDG-PET exams, but the evidence of correlation to patient pain is lacking. Limited DWI exists for inflammatory spondyloarthropathies and myopathies, but is also lacking. This is an exploratory study investigating the utility of FDG PET activity and MRI signal change around facet joints in the clinical management of low back pain. This study will help determine if such imaging biomarkers could change clinical management. Additionally, this will provide data that will be vital to planning a larger prospective study evaluating the ability of imaging biomarkers to predict response to comparison medial branch blocks and RF ablation for treatment of facet joint pain.
Primary Outcome
Concordance of high grade FDG scores with clinical impression
Conditions Studied
Interventions
- DEVICE FDG PET/MR examination.
Study Locations (1)
Minnesota
- Mayo Clinic in Rochester - Rochester
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2016-09 |
| Est. Completion | 2019-10 |
| Phase | NA |
What the finished NCT02921490 record still lists
NCT02921490 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 504-participant average among 122 other Low Back Pain trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Low Back Pain appearing as the primary indexed condition, and to 1 intervention - of which FDG PET/MR examination. is the first listed.
NCT02921490 reports a single indexed study location in Minnesota.
Frequently Asked Questions
What is clinical trial NCT02921490 about?
NCT02921490 is a clinical study titled "FDG PET/MRI Evaluation of Facet Joint Pain". Chronic pain incurs over half a trillion dollars in lost productivity (healthcare, lost wages, etc) annually. The most common source is low back pain (LBP), often from facet joints. The clinical evaluation of facet joints is challenging and anatomic imaging findings of facet joint; degenerative chan...
What is the current status of trial NCT02921490?
This trial is currently completed. It is a NA study. The enrollment target is 10 participants. The study started on 2016-09. Estimated completion is 2019-10.
What conditions does trial NCT02921490 study?
This clinical trial studies the following conditions: Low Back Pain.
What interventions are being tested in trial NCT02921490?
The interventions under investigation include: FDG PET/MR examination. (DEVICE).
Who is sponsoring clinical trial NCT02921490?
This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT02921490 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT02921490's enrollment target sits among peer trials
10 122nd of 122 higher than 1 of 122 other Low Back Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Low Back Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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