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NCT00125528 · ClinicalTrials.gov registry record · Phase 2
D-cycloserine in the Management of Chronic Low Back Pain
A Phase 2 study of Pain and Low Back Pain, sponsored by Thomas J. Schnitzer.
- Completed
- Registry status
- Phase 2
- Development phase
- 41
- Enrollment target
- 1
- Study location
NCT00125528: Completed Phase 2 study of Pain and Low Back Pain, sponsored by Thomas J. Schnitzer.
NCT00125528 is a Phase 2 study of Pain and Low Back Pain that has completed, run by Thomas J. Schnitzer. The registered enrollment target is 41 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (87% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00125528, a Phase 2 study of Pain and Low Back Pain, has completed, sponsored by Thomas J. Schnitzer.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 41 participants
- Enrollment target
- 1
- Study location
Study Summary
Pre-clinical studies in rats suggest that D-cycloserine (DCS) is effective in the management of chronic neuropathic pain. This pilot study will attempt to determine the effect of D-cycloserine in the treatment of chronic low back pain. Other aims of this study are to determine the safety of D-cycloserine in the treatment of chronic low back pain and to determine which pain measurement scales are best at measuring the efficacy of treatment.
Primary Outcome
Change in NRS score after 6 weeks of treatment as compared to baseline. The numeric rating scale is an 11-point rating scale wherein participants rated their current lower back pain intensity on a scale from 0 to 10, with 0 meaning no pain and 10 being the worst pain possible. Thus, a larger negative number indicates positive change and a higher efficacy.
Conditions Studied
Interventions
- DRUG placebo
- DRUG D-cycloserine
Study Locations (1)
Illinois
- Northwestern University Feinberg School of Medicine - Chicago
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 41 participants |
| Start Date | 2012-07 |
| Est. Completion | 2014-11 |
| Phase | Phase 2 |
What the finished NCT00125528 record still lists
NCT00125528 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 41 participants, a relatively small participant target, below the 304-participant average among 374 other Pain trials with a reported enrollment target (87% lower).
The record links to 2 conditions, with Pain appearing as the primary indexed condition, and to 2 interventions - of which placebo is the first listed.
NCT00125528 reports a single indexed study location in Illinois.
Frequently Asked Questions
What is clinical trial NCT00125528 about?
NCT00125528 is a clinical study titled "D-cycloserine in the Management of Chronic Low Back Pain". Pre-clinical studies in rats suggest that D-cycloserine (DCS) is effective in the management of chronic neuropathic pain. This pilot study will attempt to determine the effect of D-cycloserine in the treatment of chronic low back pain. Other aims of this study are to determine the safety of D-cyclos...
What is the current status of trial NCT00125528?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 41 participants. The study started on 2012-07. Estimated completion is 2014-11.
What conditions does trial NCT00125528 study?
This clinical trial studies the following conditions: Pain, Low Back Pain.
What interventions are being tested in trial NCT00125528?
The interventions under investigation include: placebo (DRUG), D-cycloserine (DRUG).
Who is sponsoring clinical trial NCT00125528?
This trial is sponsored by Thomas J. Schnitzer, which has 5 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00125528 being conducted?
This trial has 1 study location across Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00125528's enrollment target sits among peer trials
41 280th of 374 higher than 94 of 374 other Pain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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