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NCT05172934 · ClinicalTrials.gov registry record · Phase 2
Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy Pilot Trial
A Phase 2 study of Ischemic Stroke, sponsored by ProMedica Health System.
- Completed
- Registry status
- Phase 2
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT05172934: Completed Phase 2 study of Ischemic Stroke, sponsored by ProMedica Health System.
NCT05172934 is a Phase 2 study of Ischemic Stroke that has completed, run by ProMedica Health System. The registered enrollment target is 20 participants, below the 1,463-participant average among 66 other Ischemic Stroke trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05172934, a Phase 2 study of Ischemic Stroke, has completed, sponsored by ProMedica Health System.
- COMPLETED
- Registry status
- Phase 2
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
Prospective, single center, non-randomized, pilot study to assess the feasibility of IA TNK following standard of care mechanical thrombectomy (MT) in patients with AIS. Participants will receive IA TNK after achieving mTICI 2b or 2c reperfusion with standard of care MT. Patients enrolled into the study will be followed for 3 months after treatment with IA TNK.
Primary Outcome
Number of participants with any incidence of intracranial hemorrhage and neurologic worsening of at least 4 points on the National Institute of Health Stroke Scale (NIHSS), according to the European Cooperative Acute Stroke Study II (ECASS-II) criteria, within 24 hours (+/- 8 hours) of treatment with IA TNK. This measure was assessed by imaging (NCCT/MRI) done within this time frame for all the enrolled study participants. This is the primary study-specific baseline measure for the ALLY study.
Conditions Studied
Interventions
- DRUG intra-arterial tenecteplase
Study Locations (1)
Ohio
- ProMedica Toledo Hospital - Toledo
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2022-03-15 |
| Est. Completion | 2023-11-01 |
| Phase | Phase 2 |
What the finished NCT05172934 record still lists
NCT05172934 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 1,463-participant average among 66 other Ischemic Stroke trials with a reported enrollment target (99% lower).
The record links to 1 condition, with Ischemic Stroke appearing as the primary indexed condition, and to 1 intervention - of which intra-arterial tenecteplase is the first listed.
NCT05172934 reports a single indexed study location in Ohio.
Frequently Asked Questions
What is clinical trial NCT05172934 about?
NCT05172934 is a clinical study titled "Adjunctive Intra-arterial Tenecteplase Following Mechanical Thrombectomy Pilot Trial". Prospective, single center, non-randomized, pilot study to assess the feasibility of IA TNK following standard of care mechanical thrombectomy (MT) in patients with AIS. Participants will receive IA TNK after achieving mTICI 2b or 2c reperfusion with standard of care MT. Patients enrolled into the s...
What is the current status of trial NCT05172934?
This trial is currently completed. It is a Phase 2 study. The enrollment target is 20 participants. The study started on 2022-03-15. Estimated completion is 2023-11-01.
What conditions does trial NCT05172934 study?
This clinical trial studies the following conditions: Ischemic Stroke.
What interventions are being tested in trial NCT05172934?
The interventions under investigation include: intra-arterial tenecteplase (DRUG).
Who is sponsoring clinical trial NCT05172934?
This trial is sponsored by ProMedica Health System, which has 12 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05172934 being conducted?
This trial has 1 study location across Ohio. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Ischemic Stroke
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT05172934's enrollment target sits among peer trials
20 55th of 66 higher than 9 of 66 other Ischemic Stroke trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Ischemic Stroke trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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