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ClinicalTrials.gov 62 recruiting now full pipeline #74 of 28,707 conditions

Insomnia: full-pipeline trial registry

62 of 152 indexed Insomnia trials are currently recruiting.

Corpus placement: #74 of 28,707 conditions by registered trial count.

152 US clinical trials · 62 currently recruiting · #74 of 28,707 conditions by registered trial count

Insomnia: 152 US clinical trials tracked, 62 recruiting.

Insomnia is the subject of 152 registered US clinical trials on ClinicalTrials.gov, 62 of them currently open to new participants. 17 are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 9 of these trials.

Enrollment posture brief

Registry condition insomnia

OPEN 62 | RECR 41% | LATE 17 | EARLY 21 | RANK #74 | SPON 9

Nearest open-share peer: Brain Injuries, Traumatic (41% recruiting · 22 trials)

Cervical Cancer48.3%Sleep48%Stress41.8%Insomnia (this)41%Atopic Dermatitis36.4%
Open-enrollment share among volume-matched conditions near Insomnia

Insomnia lists 62 open slots (41% of 152 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Insomnia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Insomnia is recruiting above its size-band peers.

    62 of 152 indexed trials (40.8%) are open to enrollment, against a 37.1% average across 139 conditions with 100+ trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Insomnia trials is spread across many organizations.

    VA Office of Research and Development accounts for 9 of 152 trials (5.9%). 86 distinct sponsors appear on at least one study for this condition label.

  3. Typical Insomnia enrolment sits around 80 participants.

    Median target enrolment is 80 among the 152 trials that report a genuine target (sentinel values excluded). 85 of those (55.9%) plan for fewer than 100 participants.

  4. Insomnia research is mostly interventional.

    147 interventional and 5 observational studies make up this index (96.7% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 15Phase 216Phase 35Phase 412

Open and recent trials

152 total, page 3 of 4

COMPLETED NA 100 participants

Behavioral Insomnia Therapy in Primary Care

US Department of Veterans Affairs

NCT00105872

COMPLETED NA 90 participants

Impact of Bed Provision and Sleep Education

Saint Joseph's University, Philadelphia

NCT04536766

COMPLETED Phase 2 83 participants

A Polysomnographic Study to Compare the Efficacy of Gastric Retentive Zaleplon Accordion Pill to Placebo in Subjects With Insomnia

Intec Pharma

NCT01277107

COMPLETED Phase 2 80 participants

Valerian to Improve Sleep in Patients With Parkinson's Disease

National Center for Complementary and Integrative Health (NCCIH)

NCT00070928

COMPLETED NA 77 participants

Implementing and Evaluating Computer-Based Interventions for Mental Health: Testing an Implementation Strategy for VA Outpatient Care

VA Office of Research and Development

NCT03151083

COMPLETED NA 76 participants

mHealth for Breast Cancer Survivors With Insomnia

Medstar Health Research Institute

NCT05233800

COMPLETED NA 73 participants

Improving Sleep to Reduce Risk for Substance Use Disorder

Florida State University

NCT03226132

COMPLETED NA 73 participants

Effectiveness of Healthy Habits for Hospitalized Older Adults to Optimize Rehabilitation

Baylor College of Medicine

NCT04269239

COMPLETED Phase 2 70 participants

Management of Insomnia in Breast Cancer Patients

Stanford University

NCT01011218

COMPLETED Phase 4 60 participants

Eszopiclone Co-Administered With Escitalopram for Insomnia in Elderly Adults With Major Depressive Disorder

Lehigh Center for Clinical Research

NCT00813735

COMPLETED NA 56 participants

Sleep Treatment Education Program for Young Adult Cancer Survivors (STEP-YA)

Dana-Farber Cancer Institute

NCT05358951

COMPLETED NA 56 participants

Insomnia Treatment and Problems (the iTAP Study)

University of Missouri-Columbia

NCT03627832

COMPLETED NA 56 participants

CBTI-CS: A Novel Cognitive-Behavioral Treatment for Insomnia in Cancer Survivors

Dana-Farber Cancer Institute

NCT02756390

COMPLETED Phase 1 56 participants

Pharmacokinetic and Safety of Ramelteon Between Adolescents With Insomnia and Healthy Adults

Takeda

NCT00914862

COMPLETED NA 55 participants

Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)

VA Office of Research and Development

NCT02697435

COMPLETED NA 54 participants

Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)

VA Office of Research and Development

NCT02248675

COMPLETED NA 54 participants

Cognitive Behavioral Therapy for Insomnia in People With Chronic Obstructive Pulmonary Disease(COPD)

University of Illinois at Chicago

NCT01072292

COMPLETED NA 50 participants

A Computerized CBTi for Insomnia in Epilepsy

The Cleveland Clinic

NCT03632889

COMPLETED NA 50 participants

Predictors of Response to Insomnia Treatments for Gulf War Veterans

VA Office of Research and Development

NCT03208049

COMPLETED NA 49 participants

An Efficient Treatment for Posttraumatic Injury for Firefighters

Palo Alto Veterans Institute for Research

NCT05950035

COMPLETED NA 48 participants

Cognitive Training in Mild Cognitive Impairment

University of Missouri-Columbia

NCT04899089

COMPLETED NA 48 participants

Sleep, Pain and Inflammatory Processes in Older Adults With Osteoarthritis

University of Rochester

NCT01683799

COMPLETED NA 45 participants

Initial Assessment of an Internet-based Symptom Management Intervention in Early Stage Breast Cancer

University of Michigan

NCT02495155

COMPLETED Phase 4 44 participants

The Treatment of Insomnia in Patients With HIV Disease

Duke University

NCT00465972

COMPLETED 44 participants

Challenging the Inflammatory Response System in Insomnia Disorder

Beth Israel Deaconess Medical Center

NCT02261597

COMPLETED NA 41 participants

Performance Evaluation of the Dreem 3 System for Sleep Assessment in Patients With Insomnia

Dreem

NCT05438017

COMPLETED NA 33 participants

The Yoga and Insomnia Study

University of Pittsburgh

NCT05723211

COMPLETED NA 33 participants

Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors

Ohio State University Comprehensive Cancer Center

NCT01929720

COMPLETED NA 31 participants

Efficacy of Behavioral Insomnia Treatment for Chronic Migraine

Daniel Riche

NCT01314651

COMPLETED NA 30 participants

Insomnia and Osteoarthritis Study

Johns Hopkins University

NCT00374556

COMPLETED NA 30 participants

Mindfulness Based Therapy for Insomnia in Black Women

Yale University

NCT04951466

COMPLETED NA 30 participants

Bioequivalency Study of Zolpidem Tartrate Under Fed Conditions

Roxane Laboratories

NCT00602719

COMPLETED NA 30 participants

Sleep Coach: A Mobile App to Address Insomnia Symptoms Among Cancer Survivors

University of Michigan Rogel Cancer Center

NCT04827459

COMPLETED Phase 1 28 participants

Cognitive Behavioral Therapy for Insomnia in Chronic Pain Patients

National Institute of Nursing Research (NINR)

NCT00133601

COMPLETED Phase 2 28 participants

Study to Evaluate Efficacy, Safety and Tolerability of JNJ-42847922 in Participants With Insomnia Disorder Without Psychiatric Comorbidity

Janssen Research & Development

NCT02464046

COMPLETED NA 24 participants

Sleep Chatbot Intervention for Emerging Black/African American Adults

University of Delaware

NCT05956886

COMPLETED NA 23 participants

Augmenting Benzodiazepine Receptor Agonist Deprescribing With Acupuncture and Yoga Among Older Adults

Vanderbilt University Medical Center

NCT06197243

COMPLETED NA 22 participants

Treating Co-Morbid Sleep Difficulties in Veterans With Posttraumatic Stress Disorder (PTSD): A Pilot Study

Durham VA Medical Center

NCT00734799

COMPLETED NA 22 participants

Web-based Insomnia Treatment for Adolescent and Young Adult Cancer Survivors

Dana-Farber Cancer Institute

NCT03279055

COMPLETED Phase 4 21 participants

A Pilot Study of Suvorexant for Insomnia in Parkinson Disease

Burdick, Daniel, M.D.

NCT02729714

COMPLETED NA 20 participants

Bioboosti Device for Insomnia Treatment

Brigham and Women's Hospital

NCT02924116

COMPLETED NA 20 participants

Tart Cherry Juice for Sleep in Older Adults With Insomnia: A Pilot Study of Feasibility and Comprehensive Mechanisms

Courtney Millar

NCT06786494

COMPLETED NA 20 participants

Investigating the Use of taVNS to Treat Insomnia in Individuals With Breast Cancer (taVNS-insomnia-BC)

University of Alabama at Birmingham

NCT06006299

COMPLETED NA 20 participants

Cognitive Behavioral Therapy to Treat Insomnia in Persons With HIV Infection

Indiana University

NCT03390114

COMPLETED NA 13 participants

Study of Cognitive Behavioral Therapy for Insomnia (CBT-I) and Acupuncture for Insomnia and Related Distress Among Cancer Caregivers

Memorial Sloan Kettering Cancer Center

NCT03012425

COMPLETED NA 13 participants

Cognitive Behavioral Therapy for Insomnia vs. Exposure, Relaxation, and Rescripting Therapy

University of Tul

NCT03831412

COMPLETED NA 12 participants

Use of an Internet-Based Insomnia Intervention to Prevent Cognitive Decline in Adults With Mild Cognitive Impairment

University of Virginia

NCT04382365

COMPLETED Phase 4 12 participants

Eszopiclone Treatment & Cortisol Responsivity

Butler Hospital

NCT00889200

COMPLETED NA 10 participants

The Effect of White Noise In High Noise Environment

Weill Medical College of Cornell University

NCT02647138

COMPLETED NA 8 participants

Researching Effective Sleep Treatments (Project REST)

University of California, San Diego

NCT02120989

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Phase Distribution

PhaseTrial count
Phase 1 5
Phase 2 16
Phase 3 5
Phase 4 12

Named interventions

Most-linked intervention names on Insomnia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
10 trials
Placebo Other
8 trials
Cognitive Behavioral Therapy for Insomnia Behavioral
7 trials
CBT-I Behavioral
5 trials
Suvorexant Drug
5 trials
Cognitive Behavioral Therapy for Insomnia (CBT-I) Behavioral
5 trials
Eszopiclone Drug
4 trials
Trazodone Drug
4 trials

US sites by state

Facility locations filed on Insomnia trials. A trial with sites in several states counts in each.

California 25 trials
Massachusetts 22 trials
Pennsylvania 14 trials
Michigan 14 trials
New York 12 trials
Florida 12 trials
Maryland 11 trials
North Carolina 9 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Insomnia page

152 registered trials, 62 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Insomnia condition card totals 152 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.