Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Insomnia clinical trials
62 of 152 indexed Insomnia trials are currently recruiting.
152 US clinical trials · 62 currently recruiting
Insomnia is the subject of 152 registered US clinical trials on ClinicalTrials.gov, 62 of them currently open to new participants. 17 are in Phase 3-4 (later-stage) and 21 in Phase 1-2 (earlier-stage). The most active sponsor is VA Office of Research and Development, running 9 of these trials.
The research picture
Insomnia has 152 registered US clinical trials, 62 of them open to new participants right now, about 41% of the total.
- 62
- recruiting participants now
- 41%
- of trials open to enrollment
- 17
- in Phase 3–4 (later-stage)
- 9
- top sponsor: VA Office of Research and Development
Active & Recent Trials
152 total, page 3 of 4
Behavioral Insomnia Therapy in Primary Care
US Department of Veterans Affairs
NCT00105872
Impact of Bed Provision and Sleep Education
Saint Joseph's University, Philadelphia
NCT04536766
A Polysomnographic Study to Compare the Efficacy of Gastric Retentive Zaleplon Accordion Pill to Placebo in Subjects With Insomnia
Intec Pharma
NCT01277107
Valerian to Improve Sleep in Patients With Parkinson's Disease
National Center for Complementary and Integrative Health (NCCIH)
NCT00070928
Implementing and Evaluating Computer-Based Interventions for Mental Health: Testing an Implementation Strategy for VA Outpatient Care
VA Office of Research and Development
NCT03151083
mHealth for Breast Cancer Survivors With Insomnia
Medstar Health Research Institute
NCT05233800
Improving Sleep to Reduce Risk for Substance Use Disorder
Florida State University
NCT03226132
Effectiveness of Healthy Habits for Hospitalized Older Adults to Optimize Rehabilitation
Baylor College of Medicine
NCT04269239
Management of Insomnia in Breast Cancer Patients
Stanford University
NCT01011218
Eszopiclone Co-Administered With Escitalopram for Insomnia in Elderly Adults With Major Depressive Disorder
Lehigh Center for Clinical Research
NCT00813735
Sleep Treatment Education Program for Young Adult Cancer Survivors (STEP-YA)
Dana-Farber Cancer Institute
NCT05358951
Insomnia Treatment and Problems (the iTAP Study)
University of Missouri-Columbia
NCT03627832
CBTI-CS: A Novel Cognitive-Behavioral Treatment for Insomnia in Cancer Survivors
Dana-Farber Cancer Institute
NCT02756390
Pharmacokinetic and Safety of Ramelteon Between Adolescents With Insomnia and Healthy Adults
Takeda
NCT00914862
Making Better Lives: Patient-Focused Care for Low Back Pain (LBP)
VA Office of Research and Development
NCT02697435
Adjunctive Brief Behavioral Treatment of Insomnia (BBTI) for Sleep Intervention (SI)
VA Office of Research and Development
NCT02248675
Cognitive Behavioral Therapy for Insomnia in People With Chronic Obstructive Pulmonary Disease(COPD)
University of Illinois at Chicago
NCT01072292
A Computerized CBTi for Insomnia in Epilepsy
The Cleveland Clinic
NCT03632889
Predictors of Response to Insomnia Treatments for Gulf War Veterans
VA Office of Research and Development
NCT03208049
An Efficient Treatment for Posttraumatic Injury for Firefighters
Palo Alto Veterans Institute for Research
NCT05950035
Cognitive Training in Mild Cognitive Impairment
University of Missouri-Columbia
NCT04899089
Sleep, Pain and Inflammatory Processes in Older Adults With Osteoarthritis
University of Rochester
NCT01683799
Initial Assessment of an Internet-based Symptom Management Intervention in Early Stage Breast Cancer
University of Michigan
NCT02495155
The Treatment of Insomnia in Patients With HIV Disease
Duke University
NCT00465972
Challenging the Inflammatory Response System in Insomnia Disorder
Beth Israel Deaconess Medical Center
NCT02261597
Performance Evaluation of the Dreem 3 System for Sleep Assessment in Patients With Insomnia
Dreem
NCT05438017
The Yoga and Insomnia Study
University of Pittsburgh
NCT05723211
Cognitive-Behavioral Intervention for Worry, Uncertainty, and Insomnia for Cancer Survivors
Ohio State University Comprehensive Cancer Center
NCT01929720
Efficacy of Behavioral Insomnia Treatment for Chronic Migraine
Daniel Riche
NCT01314651
Insomnia and Osteoarthritis Study
Johns Hopkins University
NCT00374556
Mindfulness Based Therapy for Insomnia in Black Women
Yale University
NCT04951466
Bioequivalency Study of Zolpidem Tartrate Under Fed Conditions
Roxane Laboratories
NCT00602719
Sleep Coach: A Mobile App to Address Insomnia Symptoms Among Cancer Survivors
University of Michigan Rogel Cancer Center
NCT04827459
Cognitive Behavioral Therapy for Insomnia in Chronic Pain Patients
National Institute of Nursing Research (NINR)
NCT00133601
Study to Evaluate Efficacy, Safety and Tolerability of JNJ-42847922 in Participants With Insomnia Disorder Without Psychiatric Comorbidity
Janssen Research & Development
NCT02464046
Sleep Chatbot Intervention for Emerging Black/African American Adults
University of Delaware
NCT05956886
Augmenting Benzodiazepine Receptor Agonist Deprescribing With Acupuncture and Yoga Among Older Adults
Vanderbilt University Medical Center
NCT06197243
Treating Co-Morbid Sleep Difficulties in Veterans With Posttraumatic Stress Disorder (PTSD): A Pilot Study
Durham VA Medical Center
NCT00734799
Web-based Insomnia Treatment for Adolescent and Young Adult Cancer Survivors
Dana-Farber Cancer Institute
NCT03279055
A Pilot Study of Suvorexant for Insomnia in Parkinson Disease
Burdick, Daniel, M.D.
NCT02729714
Bioboosti Device for Insomnia Treatment
Brigham and Women's Hospital
NCT02924116
Tart Cherry Juice for Sleep in Older Adults With Insomnia: A Pilot Study of Feasibility and Comprehensive Mechanisms
Courtney Millar
NCT06786494
Investigating the Use of taVNS to Treat Insomnia in Individuals With Breast Cancer (taVNS-insomnia-BC)
University of Alabama at Birmingham
NCT06006299
Cognitive Behavioral Therapy to Treat Insomnia in Persons With HIV Infection
Indiana University
NCT03390114
Study of Cognitive Behavioral Therapy for Insomnia (CBT-I) and Acupuncture for Insomnia and Related Distress Among Cancer Caregivers
Memorial Sloan Kettering Cancer Center
NCT03012425
Cognitive Behavioral Therapy for Insomnia vs. Exposure, Relaxation, and Rescripting Therapy
University of Tul
NCT03831412
Use of an Internet-Based Insomnia Intervention to Prevent Cognitive Decline in Adults With Mild Cognitive Impairment
University of Virginia
NCT04382365
Eszopiclone Treatment & Cortisol Responsivity
Butler Hospital
NCT00889200
The Effect of White Noise In High Noise Environment
Weill Medical College of Cornell University
NCT02647138
Researching Effective Sleep Treatments (Project REST)
University of California, San Diego
NCT02120989
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 5 |
| Phase 2 | 16 |
| Phase 3 | 5 |
| Phase 4 | 12 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Insomnia Trial Landscape
152 indexed Insomnia studies · 62 recruiting (41%).
Phase mix: 17 late (III/IV) vs 21 early (I/II).
Top sponsor: VA Office of Research and Development (9 trials), 9 others listed. 50 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Insomnia?
PlainTrial tracks 152 US clinical trials for Insomnia, of which 62 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Insomnia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.