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NCT00889200 · ClinicalTrials.gov registry record · Phase 4
Eszopiclone Treatment & Cortisol Responsivity
A Phase 4 study of Insomnia, sponsored by Butler Hospital.
- Completed
- Registry status
- Phase 4
- Development phase
- 12
- Enrollment target
- 1
- Study location
NCT00889200: Completed Phase 4 study of Insomnia, sponsored by Butler Hospital.
NCT00889200 is a Phase 4 study of Insomnia that has completed, run by Butler Hospital. The registered enrollment target is 12 participants, below the 170-participant average among 151 other Insomnia trials with a reported enrollment target (93% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT00889200, a Phase 4 study of Insomnia, has completed, sponsored by Butler Hospital.
- COMPLETED
- Registry status
- Phase 4
- Development phase
- 12 participants
- Enrollment target
- 1
- Study location
Study Summary
This study was designed to use a sensitive neuroendocrine probe, the Dexamethasone/Corticotropin-Releasing Hormone (DEX/CRH) test, in a sample of healthy adults with insomnia. The primary aim was to assess cortisol reactivity before and after long-term (6 weeks) administration of eszopiclone. It was hypothesized that treatment with eszopiclone would result in a significant reduction in plasma cortisol response to the DEX/CRH test following treatment of insomnia with standard dose of eszopiclone.
Primary Outcome
Cortisol reponse to the DEX/CRH test post-treatment is the same as measured and calculated at baseline =delta(CORT).
Conditions Studied
Interventions
- DRUG eszopiclone
Study Locations (1)
Rhode Island
- Butler Hospital - Providence
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 12 participants |
| Start Date | 2007-05 |
| Est. Completion | 2009-08 |
| Phase | Phase 4 |
What the finished NCT00889200 record still lists
NCT00889200 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 12 participants, a relatively small participant target, below the 170-participant average among 151 other Insomnia trials with a reported enrollment target (93% lower).
The record links to 1 condition, with Insomnia appearing as the primary indexed condition, and to 1 intervention - of which eszopiclone is the first listed.
NCT00889200 reports a single indexed study location in Rhode Island.
Frequently Asked Questions
What is clinical trial NCT00889200 about?
NCT00889200 is a clinical study titled "Eszopiclone Treatment & Cortisol Responsivity". This study was designed to use a sensitive neuroendocrine probe, the Dexamethasone/Corticotropin-Releasing Hormone (DEX/CRH) test, in a sample of healthy adults with insomnia. The primary aim was to assess cortisol reactivity before and after long-term (6 weeks) administration of eszopiclone. It was...
What is the current status of trial NCT00889200?
This trial is currently completed. It is a Phase 4 study. The enrollment target is 12 participants. The study started on 2007-05. Estimated completion is 2009-08.
What conditions does trial NCT00889200 study?
This clinical trial studies the following conditions: Insomnia.
What interventions are being tested in trial NCT00889200?
The interventions under investigation include: eszopiclone (DRUG).
Who is sponsoring clinical trial NCT00889200?
This trial is sponsored by Butler Hospital, which has 103 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00889200 being conducted?
This trial has 1 study location across Rhode Island. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Insomnia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT00889200's enrollment target sits among peer trials
12 146th of 151 higher than 5 of 151 other Insomnia trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Insomnia trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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