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Hypertriglyceridemia
Open-data reference.
27 US clinical trials · 3 currently recruiting
Active & Recent Trials
Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia
Arrowhead Pharmaceuticals
NCT06822790
Differential Thrombogenesis by EPA and DHA Mediated by HDL
The Miriam Hospital
NCT06494488
A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol
Marea Therapeutics
NCT07199309
Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia
Arrowhead Pharmaceuticals
NCT06347133
Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol
Marea Therapeutics
NCT07028749
Study of RN0361in Adult Healthy Subjects and Adult Hypertriglyceridemic Subjects
Ikaria Bioscience Pty
NCT06471543
MN-001 in Non-alcoholic Fatty Liver Disease, Type 2 Diabetes Mellitus, and Hypertriglyceridemia
MediciNova
NCT05464784
[E]PANOVA Combined With a [S]TATIN in [P]ATIENTS With HYPERT[R]IGLYCER[I]DEMIA to Reduce Non-HDL CHOLES[T]EROL
AstraZeneca
NCT01408303
A Study Comparing The Efficacy & Safety Of Torcetrapib/Atorvastatin And Atorvastatin In Subjects With High Triglycerides
Pfizer
NCT00134498
Effects of Amino Acids on Regional Lipid Metabolism
University of Arkansas
NCT01150188
Study to Evaluate the 2-Way Interaction Between Multiple Doses of Epanova™ and a Single Dose of Rosuvastatin (Crestor®)
AstraZeneca
NCT02859129
Effects of Omega-3 Fatty Acids on Markers of Inflammation
Stanford University
NCT01129050
Pilot Study To Assess CAT-2003 in Patients With Hyperlipidemia
Catabasis Pharmaceuticals
NCT01912560
Interaction of Epanova on Warfarin Pharmacokinetic and Anticoagulant Activity and Comparison of the Effects of Epanova and Lovaza on Eicosapentaenoic Acid (EPA) and Docosahexaenoic Acid (DHA) After Low-fat Meals
AstraZeneca
NCT01431690
The Effect of Multiple Doses of Epanova® on the Multiple-Dose Pharmacokinetics of Simvastatin in Healthy Normal Subjects
AstraZeneca
NCT01486433
Predictors of Response to Fenofibrate
University of Alabama at Birmingham
NCT01023750
Boosted Lexiva With Lovaza Adjunctive Therapy in Hypertriglyceridemic, HIV-Infected Subjects
Felizarta, Franco, M.D.
NCT01010399
PK Study Comparing Metformin Eicosapentaenoate to a Combined Dose of Metformin Hydrochloride and Ethyl Ester EPA
Thetis Pharmaceuticals
NCT02113163
Niacin for Treatment of Elevated Cholesterol and Triglycerides in HIV-Infected Patients
National Institute of Allergy and Infectious Diseases (NIAID)
NCT00046267
Vascular and Lipid Effects of Omega-3 Fatty Acids in People With Moderately Elevated Triglycerides
Penn State University
NCT00504309
Effect of Maraviroc on Metabolic Function in Obese Subjects (Phase I)
Washington University School of Medicine
NCT01133210
Effects of Diet Interventions on Monocytes in Metabolic Syndrome
Baylor College of Medicine
NCT03591588
Changes in Lipids and Safety of Raltegravir in HIV+ Patients With Hyperlipidemia While on Current Standard Therapy
The Miriam Hospital
NCT00887653
Pilot Study To Assess CAT-2003 in Patients With Severe Hypertriglyceridemia
Catabasis Pharmaceuticals
NCT01968720
Study of Gemcabene in Adults With FPLD
Elif Oral
NCT03508687
Novel Therapies for Metabolic Complications of Lipodystrophies
University of Texas Southwestern Medical Center
NCT00457938
Regulation of Sterol Homeostasis
US Department of Veterans Affairs
NCT00018720
Phase Distribution
| Phase | Trial count |
|---|---|
| Early Phase 1 | 8 |
| Phase 2 | 5 |
| Phase 3 | 5 |
| Phase 4 | 1 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Hypertriglyceridemia Trial Landscape
ClinicalTrials.gov lists 27 US studies indexed under Hypertriglyceridemia, and 3 of those are currently open to recruitment — roughly 11% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Hypertriglyceridemia shows 6 late-stage studies (Phase 3 and Phase 4 combined) alongside 13 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Hypertriglyceridemia is led by AstraZeneca with 4 indexed trials, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 27 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Hypertriglyceridemia?
PlainTrial tracks 27 US clinical trials for Hypertriglyceridemia, of which 3 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Hypertriglyceridemia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.