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NCT06347133 · ClinicalTrials.gov registry record · Phase 3
Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia
A Phase 3 study of Hypertriglyceridemia, sponsored by Arrowhead Pharmaceuticals.
- Active
- Registry status
- Phase 3
- Development phase
- 1,456
- Enrollment target
- 20
- Study locations
NCT06347133 is a Phase 3 study of Hypertriglyceridemia that is active but no longer recruiting, run by Arrowhead Pharmaceuticals. The registered enrollment target is 1,456 participants, above the 118-participant average among 25 other Hypertriglyceridemia trials with a reported enrollment target (1134% higher). The trial reports 20 study locations across 4 states.
The verdict
NCT06347133, a Phase 3 study of Hypertriglyceridemia, is active but no longer recruiting, sponsored by Arrowhead Pharmaceuticals.
- ACTIVE NOT RECRUITING
- Registry status
- Phase 3
- Development phase
- 1,456 participants
- Enrollment target
- 20
- Study locations
Study Summary
This Phase 3 study will evaluate the safety and efficacy of plozasiran injection (ARO-APOC3) in adult participants with hypertriglyceridemia (HTG). After providing informed consent eligible participants will be randomized to receive 4 doses (once every 3 months) of plozasiran or placebo and be evaluated for efficacy and safety.
Conditions Studied
Interventions
- DRUG Placebo
- DRUG Plozasiran Injection
Study Locations (20)
California
- Research Site 3 - Beverly Hills
- Research Site 4 - Canoga Park
- Research Site 5 - Garden Grove
- Research Site 6 - Huntington Beach
- Research Site 7 - Lake Forest
- Research Site 8 - Lincoln
- Research Site 9 - Long Beach
- Research Site 10 - Montclair
- Research Site 11 - Oxnard
- Research Site 12 - Redding
- Research Site 13 - Van Nuys
Florida
- Research Site 15 - Clearwater
- Research Site 16 - Hialeah
- Research Site 17 - Lake City
- Research Site 18 - Miami Lakes
- Research Site 19 - Mt. Dora
- Research Site 20 - North Miami Beach
Alabama
- Research Site 1 - Birmingham
- Research Site 2 - Mobile
Colorado
- Research Site 14 - Colorado Springs
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,456 participants |
| Start Date | 2024-05-21 |
| Est. Completion | 2026-09 |
| Phase | Phase 3 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT06347133
The ClinicalTrials.gov registry entry for NCT06347133 describes a study currently listed as active not recruiting, categorized as Phase 3. The registered enrollment target is 1,456 participants, a figure that helps gauge the scale of data the investigators plan to collect, above the 118-participant average among 25 other Hypertriglyceridemia trials with a reported enrollment target (1134% higher). The listed sponsor is Arrowhead Pharmaceuticals, which has 15 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Hypertriglyceridemia appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.
NCT06347133 reports 20 study locations spanning 4 distinct geographic areas - top geographies include California, Florida, Alabama.
Frequently Asked Questions
What is clinical trial NCT06347133 about?
NCT06347133 is a clinical study titled "Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia". This Phase 3 study will evaluate the safety and efficacy of plozasiran injection (ARO-APOC3) in adult participants with hypertriglyceridemia (HTG). After providing informed consent eligible participants will be randomized to receive 4 doses (once every 3 months) of plozasiran or placebo and be evalu...
What is the current status of trial NCT06347133?
This trial is currently active not recruiting. It is a Phase 3 study. The enrollment target is 1,456 participants. The study started on 2024-05-21. Estimated completion is 2026-09.
What conditions does trial NCT06347133 study?
This clinical trial studies the following conditions: Hypertriglyceridemia.
What interventions are being tested in trial NCT06347133?
The interventions under investigation include: Placebo (DRUG), Plozasiran Injection (DRUG).
Who is sponsoring clinical trial NCT06347133?
This trial is sponsored by Arrowhead Pharmaceuticals, which has 15 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06347133 being conducted?
This trial has 20 study locations across Alabama, California, Colorado, Florida. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
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