Arrowhead Pharmaceuticals
Trial Pipeline
A Phase 3 Study of Zodasiran in Adolescent and Adult Subjects With Homozygous Familial Hypercholesterolemia (YOSEMITE)
NCT07037771
Study of Plozasiran in Adults With Severe Hypertriglyceridemia at Risk of Acute Pancreatitis
NCT06880770
Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia
NCT06822790
Study of Plozasiran in Adults With Severe Hypertriglyceridemia
NCT06347016
Study of Plozasiran (ARO-APOC3) in Adults With Severe Hypertriglyceridemia
NCT06347003
Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia
NCT06347133
Study of ARO-ANG3 in Participants With Homozygous Familial Hypercholesterolemia (HOFH)
NCT05217667
Study of ARO-APOC3 (Plozasiran) in Adults With Familial Chylomicronemia Syndrome (FCS)
NCT05089084
Study of ARO-APOC3 in Adults With Dyslipidemia
NCT05413135
Study of ARO-ANG3 in Adults With Mixed Dyslipidemia
NCT04832971
Study of ARO-HIF2 in Patients With Advanced Clear Cell Renal Cell Carcinoma
NCT04169711
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 3 |
| Phase 3 | 7 |
What the Pipeline for Arrowhead Pharmaceuticals Shows
According to the ClinicalTrials.gov registry, Arrowhead Pharmaceuticals is linked to 11 US clinical trials across every stage of research activity. Of those, 3 studies are currently recruiting — about 27% of the sponsor's indexed portfolio — and 3 are already marked complete, representing roughly 27% of the total. Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
The phase mix for Arrowhead Pharmaceuticals reports 7 late-stage studies (Phase 3 and Phase 4 combined) and 4 earlier-phase studies (Phase 1 and Phase 2). A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work — safety, dosing, and early signal detection — and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
The top therapeutic focus area indexed for Arrowhead Pharmaceuticals is Severe Hypertriglyceridemia with 3 linked trials, and 6 other condition areas appear in the top list above. That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice — verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology — how this data is sourced, computed, and verified.