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ACTIVE NOT RECRUITING Phase 2

Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol

NCT07028749 · View on ClinicalTrials.gov ↗

Study Summary

The primary objective of the study is to evaluate the effect of MAR001 compared to placebo on levels of the TG and RC in adults with elevated TG and RC.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG MAR001

Study Locations (20)

Alabama

  • Marea Site 328 — Anniston
  • Marea Site 329 — Mobile

Florida

  • Marea Site 302 — Boca Raton
  • Marea Site 307 — Port Saint Lucie

Georgia

  • Marea Site 310 — Columbus
  • Marea Site 319 — Peachtree Corners

Illinois

  • Marea Site 317 — Park Ridge
  • Marea Site 325 — Springfield

Missouri

  • Marea Site 330 — Kansas City
  • Marea Site 305 — St Louis

New York

  • Marea Site 304 — Great Neck
  • Marea Site 318 — New Windsor

North Carolina

  • Marea Site 303 — Greensboro
  • Marea Site 315 — Winston-Salem

South Carolina

  • Marea Site 314 — Greenville
  • Marea Site 320 — Little River

Trial Details

FieldValue
Enrollment Target 216 participants
Start Date 2025-06-30
Est. Completion 2026-12
Phase Phase 2

Sponsor

Marea Therapeutics

3 total trials

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Full Details on ClinicalTrials.gov ↗

What the Registry Record Tells You About NCT07028749

The ClinicalTrials.gov registry entry for NCT07028749 describes a study currently listed as active not recruiting. It is categorized as Phase 2, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 216 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Marea Therapeutics, which has 3 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.

The record links to 1 condition, with Hypertriglyceridemia appearing as the primary indexed condition, and to 2 interventions — of which Placebo is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.

Geographic footprint matters for practical reasons: NCT07028749 reports 20 study locations spanning 12 distinct geographic areas — top geographies include Alabama, Florida, Georgia. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.

Frequently Asked Questions

What is clinical trial NCT07028749 about?

NCT07028749 is a clinical study titled "Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol". The primary objective of the study is to evaluate the effect of MAR001 compared to placebo on levels of the TG and RC in adults with elevated TG and RC.

What is the current status of trial NCT07028749?

This trial is currently active not recruiting. It is a Phase 2 study. The enrollment target is 216 participants. The study started on 2025-06-30. Estimated completion is 2026-12.

What conditions does trial NCT07028749 study?

This clinical trial studies the following conditions: Hypertriglyceridemia. These conditions were identified from the trial registry and reflect the primary focus areas of the research.

What interventions are being tested in trial NCT07028749?

The interventions under investigation include: Placebo (DRUG), MAR001 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.

Who is sponsoring clinical trial NCT07028749?

This trial is sponsored by Marea Therapeutics, which has 3 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.

Where is trial NCT07028749 being conducted?

This trial has 20 study locations across Alabama, Arkansas, Connecticut, Florida, Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial