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NCT00018720 · ClinicalTrials.gov registry record
Regulation of Sterol Homeostasis
A clinical trial of Hypertriglyceridemia, sponsored by US Department of Veterans Affairs.
- Completed
- Registry status
- 1
- Study location
NCT00018720 is a study of Hypertriglyceridemia that has completed, run by US Department of Veterans Affairs. The trial reports 1 study location across 1 state.
The verdict
NCT00018720, a study of Hypertriglyceridemia, has completed, sponsored by US Department of Veterans Affairs.
- COMPLETED
- Registry status
- 1
- Study location
Study Summary
The purpose of this study is to determine how people with high triglycerides metabolize and absorb bile acids, compounds made in the body from cholesterol. This project has two objectives: A) To define the mechanism of impaired bile acid absorption in hypertriglyceridemia (specifically we will determine if the active or passive component of absorption is abnormal) and B) to determine the contribution of an alternative pathway of bile acid synthesis which begins with 27-hydroxylation of cholesterol. Because 27-hydroxylase is present in endothelial cells as well as liver, this pathway may play a role in removal of cholesterol from incipient atherosclerotic plaque.
Conditions Studied
Study Locations (1)
Minnesota
- VA Medical Center - Minneapolis
Trial Details
| Field | Value |
|---|---|
| Start Date | 1996-04 |
| Est. Completion | 2000-12 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT00018720
The ClinicalTrials.gov registry entry for NCT00018720 describes a study currently listed as completed, categorized as an unspecified phase. An enrollment target was not published in the registry record, which is common for early-stage or observational entries. The listed sponsor is US Department of Veterans Affairs, which has 632 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Hypertriglyceridemia appearing as the primary indexed condition, and to 0 interventions.
NCT00018720 reports 1 study location spanning 1 distinct geographic area - top geographies include Minnesota.
Frequently Asked Questions
What is clinical trial NCT00018720 about?
NCT00018720 is a clinical study titled "Regulation of Sterol Homeostasis". The purpose of this study is to determine how people with high triglycerides metabolize and absorb bile acids, compounds made in the body from cholesterol. This project has two objectives: A) To define the mechanism of impaired bile acid absorption in hypertriglyceridemia (specifically we will dete...
What is the current status of trial NCT00018720?
This trial is currently completed. The study started on 1996-04. Estimated completion is 2000-12.
What conditions does trial NCT00018720 study?
This clinical trial studies the following conditions: Hypertriglyceridemia.
Who is sponsoring clinical trial NCT00018720?
This trial is sponsored by US Department of Veterans Affairs, which has 632 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT00018720 being conducted?
This trial has 1 study location across Minnesota. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Hypertriglyceridemia
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
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Long-Term Safety and Efficacy of Plozasiran in Adults With Hypertriglyceridemia
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-
A Mechanistic Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol
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-
Differential Thrombogenesis by EPA and DHA Mediated by HDL
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-
Phase 3 Study of Plozasiran in Adults With Hypertriglyceridemia
ACTIVE NOT RECRUITING · Phase 3
-
Study of RN0361in Adult Healthy Subjects and Adult Hypertriglyceridemic Subjects
ACTIVE NOT RECRUITING · Phase 1
-
Study of MAR001 in Adults With Elevated Triglycerides and Remnant Cholesterol
ACTIVE NOT RECRUITING · Phase 2
Read our methodology - how this data is sourced, computed, and verified.
Related
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