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Hyperlipidemia clinical trials
4 of 36 indexed Hyperlipidemia trials are currently recruiting.
36 US clinical trials · 4 currently recruiting
Hyperlipidemia is the subject of 36 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 11 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Amgen, running 3 of these trials.
The research picture
Hyperlipidemia has 36 registered US clinical trials, 4 of them open to new participants right now, about 11% of the total.
- 4
- recruiting participants now
- 11%
- of trials open to enrollment
- 11
- in Phase 3–4 (later-stage)
- 3
- top sponsor: Amgen
Active & Recent Trials
36 total, page 1 of 1
A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)
Merck Sharp & Dohme
NCT07216482
Implementation of an Algorithm- and Multi-professional Team-supported Strategy to Improve Lipid Management of Patients With Atherosclerotic Cardiovascular Disease
Colorado Prevention Center
NCT07334834
Inspire HER: Inspiring the Heart and Emotions for Radical Health
University of Alabama at Birmingham
NCT06966258
Targeting Metabolic Syndrome From the Emergency Department Through Mixed-Methods: Pilot Trial
Indiana University
NCT07119658
Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT02262806
Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NCT02262832
Body Worlds 3 Nutrition Display
Oregon Health and Science University
NCT00669500
Improving Quality With Outpatient Decision Support
Agency for Healthcare Research and Quality (AHRQ)
NCT00225628
A Coronary IVUS Study to Compare Torcetrapib/Atorvastatin to Atorvastatin Alone in Subjects With Coronary Heart Disease
Pfizer
NCT00134173
Cholesterol and Pharmacogenetic Study
UCSF Benioff Children's Hospital Oakland
NCT00451828
LAPLACE-TIMI 57: Low-density Lipoprotein Cholesterol (LDL-C) Assessment With PCSK9 monoclonaL Antibody Inhibition Combined With Statin thErapy
Amgen
NCT01380730
Unmet Social Needs Study
VA Office of Research and Development
NCT04977583
The Health Access and Recovery Peer Program
Emory University
NCT01725815
Reduction of LDL-C With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study-2
Amgen
NCT01763918
The SCCS Polypill Pilot Trial
Vanderbilt University
NCT02278471
Effects of Resistance and Aerobic Exercise on Cardiovascular Health
Duke University
NCT00275145
Evaluate Low Doses of AEGR-733 on Hepatic Fat Accumulation by MRS
Aegerion Pharmaceuticals
NCT00559962
Veterans Walk for Health Study
US Department of Veterans Affairs
NCT00123435
Federal Study of Adherence to Medications in the Elderly (FAME)
Walter Reed Army Medical Center
NCT00393419
Eating Peanuts for Health
Purdue University
NCT01886326
Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabetes Patients Whose Blood Glucose Isn't Completely Controlled With Metformin
Daiichi Sankyo
NCT00484419
Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects
Amgen
NCT01375764
Low Carbohydrate Diet Compared to Calorie and Fat Restricted Diet in Patients With Obesity and Type II Diabetes
US Department of Veterans Affairs
NCT00108459
Colesevelam Treatment for Impaired Fasting Glucose During Niacin Therapy
Radiant Research
NCT01239004
Expanding Comparative Effectiveness Research (CER) Capability Through Complex Patient Relationship Management
Denver Health and Hospital Authority
NCT01391585
Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of K-312 in Healthy Subjects
Kowa Research Institute
NCT02676596
Efficacy and Safety Study of Lipid-Lowering Effects of XueZhiKang (XZK) in Patients With Hyperlipidemia
Beijing Peking University WBL Biotech Co.
NCT01327014
Evaluation of Pharmacist Interventions in Lipid Management for Secondary Prevention
Wake Forest University Health Sciences
NCT06647238
Effect of Pterostilbene on Cholesterol, Blood Pressure and Oxidative Stress
University of Mississippi Medical Center
NCT01267227
Telephone Based Management of Hyperlipidemia
Temple University
NCT01212159
The Triglyceride Lowering Effect of an Omega-3 Fat (DHA) in Addition to Statin Therapy for Patients With CAD or Diabetes
Maine Center for Lipids and Cardiovascular Health
NCT00360217
Effects of Use of a Connected Pillbox On Medication Adherence
University of Pennsylvania
NCT02593032
Switch to Atazanavir and Brachial Artery Reactivity (SABAR) Study
Northwestern University
NCT00225017
Antihyperlipidemic Effects of Oyster Mushrooms
National Center for Complementary and Integrative Health (NCCIH)
NCT00069524
Changes in Lipids and Safety of Raltegravir in HIV+ Patients With Hyperlipidemia While on Current Standard Therapy
The Miriam Hospital
NCT00887653
Biosynthesis of PGD2 in Vivo
University of Pennsylvania
NCT01275300
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 2 |
| Phase 2 | 8 |
| Phase 3 | 8 |
| Phase 4 | 3 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Hyperlipidemia Trial Landscape
36 indexed Hyperlipidemia studies · 4 recruiting (11%).
Phase mix: 11 late (III/IV) vs 10 early (I/II).
Top sponsor: Amgen (3 trials), 9 others listed. 36 shown below, recruiting first.
How to read this condition's trial landscape
That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Hyperlipidemia?
PlainTrial tracks 36 US clinical trials for Hyperlipidemia, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Hyperlipidemia?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology - how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.