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ClinicalTrials.gov 4 recruiting now full pipeline

Hyperlipidemia: full-pipeline trial registry

4 of 36 indexed Hyperlipidemia trials are currently recruiting.

Corpus placement: #419 of 28,707 conditions by registered trial count.

36 US clinical trials · 4 currently recruiting · #419 of 28,707 conditions by registered trial count

Hyperlipidemia: 36 US clinical trials tracked, 4 recruiting.

Hyperlipidemia is the subject of 36 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 11 are in Phase 3-4 (later-stage) and 10 in Phase 1-2 (earlier-stage). The most active sponsor is Amgen, running 3 of these trials.

Enrollment posture brief

Registry condition hyperlipidemia

OPEN 4 | RECR 11% | LATE 11 | EARLY 10 | RANK #419 | SPON 3

Nearest open-share peer: Acute Heart Failure (11% recruiting · 9 trials)

Dysphagia63.9%Cognition50%Chronic Myeloid Leukemia38.9%Hyperlipidemia (this)11%Coronary Disease2.8%
Open-enrollment share among volume-matched conditions near Hyperlipidemia

Hyperlipidemia lists 4 open slots (11% of 36 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Hyperlipidemia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Hyperlipidemia is recruiting below its size-band peers.

    4 of 36 indexed trials (11.1%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. Sponsorship of Hyperlipidemia trials is spread across many organizations.

    Amgen accounts for 3 of 36 trials (8.3%). 31 distinct sponsors appear on at least one study for this condition label.

  3. Typical Hyperlipidemia enrolment sits around 156 participants.

    Median target enrolment is 156 among the 36 trials that report a genuine target (sentinel values excluded). 13 of those (36.1%) plan for fewer than 100 participants.

  4. Hyperlipidemia research is mostly interventional.

    36 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12Phase 28Phase 38Phase 43

Open and recent trials

36 total, page 1 of 1

RECRUITING Phase 3 975 participants

A Clinical Study of Enlicitide in Participants With High Cholesterol (MK-0616-037)

Merck Sharp & Dohme

NCT07216482

RECRUITING NA 100 participants

Implementation of an Algorithm- and Multi-professional Team-supported Strategy to Improve Lipid Management of Patients With Atherosclerotic Cardiovascular Disease

Colorado Prevention Center

NCT07334834

RECRUITING NA 90 participants

Inspire HER: Inspiring the Heart and Emotions for Radical Health

University of Alabama at Birmingham

NCT06966258

RECRUITING NA 20 participants

Targeting Metabolic Syndrome From the Emergency Department Through Mixed-Methods: Pilot Trial

Indiana University

NCT07119658

ACTIVE NOT RECRUITING Phase 2 29 participants

Compassionate Use of Metreleptin in Previously Treated People With Partial Lipodystrophy

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT02262806

ACTIVE NOT RECRUITING Phase 3 24 participants

Compassionate Use of Metreleptin in Previously Treated People With Generalized Lipodystrophy

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NCT02262832

COMPLETED NA 3,188 participants

Body Worlds 3 Nutrition Display

Oregon Health and Science University

NCT00669500

COMPLETED NA 3,000 participants

Improving Quality With Outpatient Decision Support

Agency for Healthcare Research and Quality (AHRQ)

NCT00225628

COMPLETED Phase 3 1,100 participants

A Coronary IVUS Study to Compare Torcetrapib/Atorvastatin to Atorvastatin Alone in Subjects With Coronary Heart Disease

Pfizer

NCT00134173

COMPLETED Phase 4 1,000 participants

Cholesterol and Pharmacogenetic Study

UCSF Benioff Children's Hospital Oakland

NCT00451828

COMPLETED Phase 2 631 participants

LAPLACE-TIMI 57: Low-density Lipoprotein Cholesterol (LDL-C) Assessment With PCSK9 monoclonaL Antibody Inhibition Combined With Statin thErapy

Amgen

NCT01380730

COMPLETED NA 479 participants

Unmet Social Needs Study

VA Office of Research and Development

NCT04977583

COMPLETED NA 400 participants

The Health Access and Recovery Peer Program

Emory University

NCT01725815

COMPLETED Phase 3 331 participants

Reduction of LDL-C With PCSK9 Inhibition in Heterozygous Familial Hypercholesterolemia Disorder Study-2

Amgen

NCT01763918

COMPLETED Phase 2 303 participants

The SCCS Polypill Pilot Trial

Vanderbilt University

NCT02278471

COMPLETED Phase 2 261 participants

Effects of Resistance and Aerobic Exercise on Cardiovascular Health

Duke University

NCT00275145

COMPLETED Phase 2 260 participants

Evaluate Low Doses of AEGR-733 on Hepatic Fat Accumulation by MRS

Aegerion Pharmaceuticals

NCT00559962

COMPLETED NA 254 participants

Veterans Walk for Health Study

US Department of Veterans Affairs

NCT00123435

COMPLETED NA 200 participants

Federal Study of Adherence to Medications in the Elderly (FAME)

Walter Reed Army Medical Center

NCT00393419

COMPLETED NA 196 participants

Eating Peanuts for Health

Purdue University

NCT01886326

COMPLETED Phase 3 169 participants

Effects of Colesevelam HCl, Rosiglitazone, Sitagliptin on Control of Blood Glucose and Lipids in Type 2 Diabetes Patients Whose Blood Glucose Isn't Completely Controlled With Metformin

Daiichi Sankyo

NCT00484419

COMPLETED Phase 2 160 participants

Goal Achievement After Utilizing an Anti-PCSK9 Antibody in Statin Intolerant Subjects

Amgen

NCT01375764

COMPLETED Phase 3 156 participants

Low Carbohydrate Diet Compared to Calorie and Fat Restricted Diet in Patients With Obesity and Type II Diabetes

US Department of Veterans Affairs

NCT00108459

COMPLETED Phase 4 140 participants

Colesevelam Treatment for Impaired Fasting Glucose During Niacin Therapy

Radiant Research

NCT01239004

COMPLETED NA 135 participants

Expanding Comparative Effectiveness Research (CER) Capability Through Complex Patient Relationship Management

Denver Health and Hospital Authority

NCT01391585

COMPLETED Phase 1 120 participants

Study to Investigate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of K-312 in Healthy Subjects

Kowa Research Institute

NCT02676596

COMPLETED Phase 2 116 participants

Efficacy and Safety Study of Lipid-Lowering Effects of XueZhiKang (XZK) in Patients With Hyperlipidemia

Beijing Peking University WBL Biotech Co.

NCT01327014

COMPLETED NA 80 participants

Evaluation of Pharmacist Interventions in Lipid Management for Secondary Prevention

Wake Forest University Health Sciences

NCT06647238

COMPLETED Phase 2 80 participants

Effect of Pterostilbene on Cholesterol, Blood Pressure and Oxidative Stress

University of Mississippi Medical Center

NCT01267227

COMPLETED Phase 4 70 participants

Telephone Based Management of Hyperlipidemia

Temple University

NCT01212159

COMPLETED NA 60 participants

The Triglyceride Lowering Effect of an Omega-3 Fat (DHA) in Addition to Statin Therapy for Patients With CAD or Diabetes

Maine Center for Lipids and Cardiovascular Health

NCT00360217

COMPLETED NA 50 participants

Effects of Use of a Connected Pillbox On Medication Adherence

University of Pennsylvania

NCT02593032

COMPLETED Phase 3 50 participants

Switch to Atazanavir and Brachial Artery Reactivity (SABAR) Study

Northwestern University

NCT00225017

COMPLETED Phase 1 20 participants

Antihyperlipidemic Effects of Oyster Mushrooms

National Center for Complementary and Integrative Health (NCCIH)

NCT00069524

COMPLETED Phase 3 20 participants

Changes in Lipids and Safety of Raltegravir in HIV+ Patients With Hyperlipidemia While on Current Standard Therapy

The Miriam Hospital

NCT00887653

COMPLETED NA 9 participants

Biosynthesis of PGD2 in Vivo

University of Pennsylvania

NCT01275300

Phase Distribution

PhaseTrial count
Phase 1 2
Phase 2 8
Phase 3 8
Phase 4 3

Named interventions

Most-linked intervention names on Hyperlipidemia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Placebo Drug
5 trials
Evolocumab Biological
3 trials
Placebo to Evolocumab Other
2 trials
Metreleptin Drug
2 trials
HARP Intervention Behavioral
1 trials
Self Monitoring Lipid Analyzer Device
1 trials
Pterostilbene 125 mg twice daily Drug
1 trials
Grape Extract Drug
1 trials

US sites by state

Facility locations filed on Hyperlipidemia trials. A trial with sites in several states counts in each.

California 11 trials
Pennsylvania 8 trials
Ohio 6 trials
Indiana 6 trials
Maryland 5 trials
Illinois 5 trials
Florida 5 trials
Colorado 5 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Hyperlipidemia page

36 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 4 Hyperlipidemia trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Amgen sponsors the most Hyperlipidemia trials on record, review their full trial history before evaluating a specific study. See Amgen's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Hyperlipidemia condition card totals 36 registered trials; most-linked intervention Placebo; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.